| chronotherapy | The adaptation of the administration of drugs to circadian rhythms. The concept is based on the response of biological functions to time-related events, such as the low point in epinephrine levels between 10 p.m. And 4 a.m. Or the elevated histamine levels between midnight and 4 a.m. The treatment is aimed at supporting normal rhythms or modifying therapy based on known variations in body rhythms. While chronotherapy is commonly used in cancer chemotherapy, it is not restricted to cancer therapy or to chemotherapy. (12 Dec 1998) |
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Synonyms : Chronotherapies
| chronotherapy |
Use of treatment timed according to the stages in the sensitivity- resistance cycles of target (or non- target) tissues and organs (or of the organism as a whole) to enhance the desired pharmacologic effect and/or reduce undesirable side effects of drugs or other therapeutic agents. [American Assoc. of Medical Chronobiology & Chronotherapeutics, Glossary, 2000] http://www.aamcc.org/glossary.htm
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