| CAP | camptodactyly-arthropathy-pericarditis [syndrome]; Canada Assistance Plan; capsule; captopril; catab... |
|---|---|
| CAT | California Achievement Test; capillary agglutination test; catalase; cataract; catecholamine; Childr... |
| CHL | Chinese hamster lung; chlorambucil; chloramphenicol |
| CMC | carboxymethylcellulose; care management continuity; carpometacarpal; cell-mediated cytolysis or cyto... |
| CSMP | chloramphenicol-sensitive microsomal protein |
| OA | Ophthalmic Artery |
|---|---|
| SOV | superior ophthalmic vein |
| CAM | Chloramphenicol |
| CAP | Chloramphenicol |
| CM | Chloramphenicol |
| chloramphenicol | <drug> A broad-spectrum antibiotic that inhibits bacterial protein synthesis in prokaryotes and in mitochondria and chloroplasts by acting on the 50S ribosomal subunit. It was first isolated from the fungus like bacterium Streptomyces venezuelae but is now produced synthetically. It is relatively toxic but finds wide application in medicine. (01 Dec 1998) |
|---|---|
| chloramphenicol 3'-O-phosphotransferase | <enzyme> Phosphorylates the 3'-oh position of chloramphenicol producing a metabolite which confers resistance to chloramphenicol when introduced into a chloramphenicol-sensitive host Registry number: EC 2.7.1.- Synonym: cpt protein, cpt gene product (26 Jun 1999) |
| chloramphenicol acetyltransferase | <enzyme> A bacterial enzyme that inactivates the antibiotic chloramphenicol by acetylation. Widely used as a reporter gene for examining the control of eucaryotic gene expression. Acronym: CAT (08 Mar 2000) |
| chloramphenicol acetyltransferase assay | <investigation> A lab technique used to determine whether a given fragment of DNA has a promoter on it to encourage transcription to occur, by attaching the gene (called the CAT gene) which codes for the CAT enzyme to it, and observing whether the CAT enzyme is produced. (05 Jan 1998) |
| chloramphenicol acetyltransferase gene | <molecular biology> A gene which codes for the CAT enzyme (the enzyme chloramphenicol acetyltransferase), which helps transfer an acetyl group (a CH3CO- group) to chloramphenicol, an antibiotic. The CAT gene is an important part of CAT assays. (09 Oct 1997) |
| chloramphenicol amidase | <enzyme> Mouse liver microsomal enzyme which cleaves dichloro-acetyl group from chloramphenicol Registry number: EC 3.5.1.- Synonym: chloramphenicol hydrolase. (26 Jun 1999) |
| chloramphenicol o-acetyltransferase | <enzyme> An enzyme that catalyses the acetylation of chloramphenicol to yield chloramphenicol 3-acetate. Since chloramphenicol 3-acetate does not bind to bacterial ribosomes and is not an inhibitor of peptidyltransferase, the enzyme is responsible for the naturally occurring chloramphenicol resistance in bacteria. The enzyme, for which variants are known, is found in both gram-negative and gram-positive bacteria. Chemical name: Acetyl-CoA-chloramphenicol 3-O-acetyltransferase Registry number: EC 2.3.1.28 (12 Dec 1998) |
| chloramphenicol palmitate | <chemical> Same action and use as chloramphenicol. (05 Mar 2000) |
| chloramphenicol resistance | <microbiology, pharmacology> Nonsusceptibility of a bacterium to the action of chloramphenicol, a potent inhibitor of protein synthesis in the 50s ribosomal subunit where amino acids are added to nascent bacterial polypeptides. (12 Dec 1998) |
| chloramphenicol sodium succinate | <chemical> Chloramphenicol-alpha-(sodium succinate);the water-soluble sodium succinate derivative of chloramphenicol, suitable for parenteral administration; antibacterial activity, uses, and side effects are similar to those of the parent compound. (05 Mar 2000) |
| meningeal branch of ophthalmic nerve | <anatomy, nerve> See: tentorial nerve. (05 Mar 2000) |
| superior ophthalmic vein | <anatomy, vein> Begins anteriorly from the nasofrontal vein, passes along the upper part of the medial wall of the orbit, passes through the superior orbital fissure, to empty into the cavernous sinus. Synonym: vena ophthalmica superior. (05 Mar 2000) |
| inferior ophthalmic vein | <anatomy, vein> Arises from the inferior palpebral and lacrimal veins and divides into two terminal branches, one of which runs to the pterygoid plexus while the other joins the superior ophthalmic vein or empties into the cavernous sinus. Synonym: vena ophthalmica inferior. (05 Mar 2000) |
| ophthalmic | <anatomy> Pertaining to the eye. (18 Nov 1997) |
| ophthalmic acid | A tripeptide occurring in lens, similar to glutathione but differing in the replacement of cysteine by alpha-amino-n-butyric acid (i.e., in the replacement of -SH by -CH3); a potent inhibitor of glyoxalase. Compare: norophthalmic acid. (05 Mar 2000) |
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