| acetyl-CoA | acetyl coenzyme A |
|---|---|
| NAPA | N-acetyl-p-aminophenol; N-acetyl procainamide |
| GT | gait training; galactosyl transferase; gastrostomy; generation time; genetic therapy; gingiva treatm... |
| CAP | camptodactyly-arthropathy-pericarditis [syndrome]; Canada Assistance Plan; capsule; captopril; catab... |
| CAT | California Achievement Test; capillary agglutination test; catalase; cataract; catecholamine; Childr... |
| CAT | LTR)-chloramphenicol acetyl transferase |
|---|---|
| acetyl-CoA | Acetyl coenzyme A |
| HAT | Histone acetyl transferase |
| SSAT | Spermidine/Spermine N(1)-acetyl transferase |
| AT | acetyl transferase |
| chloramphenicol | <drug> A broad-spectrum antibiotic that inhibits bacterial protein synthesis in prokaryotes and in mitochondria and chloroplasts by acting on the 50S ribosomal subunit. It was first isolated from the fungus like bacterium Streptomyces venezuelae but is now produced synthetically. It is relatively toxic but finds wide application in medicine. (01 Dec 1998) |
|---|---|
| chloramphenicol 3'-O-phosphotransferase | <enzyme> Phosphorylates the 3'-oh position of chloramphenicol producing a metabolite which confers resistance to chloramphenicol when introduced into a chloramphenicol-sensitive host Registry number: EC 2.7.1.- Synonym: cpt protein, cpt gene product (26 Jun 1999) |
| chloramphenicol acetyltransferase | <enzyme> A bacterial enzyme that inactivates the antibiotic chloramphenicol by acetylation. Widely used as a reporter gene for examining the control of eucaryotic gene expression. Acronym: CAT (08 Mar 2000) |
| chloramphenicol acetyltransferase assay | <investigation> A lab technique used to determine whether a given fragment of DNA has a promoter on it to encourage transcription to occur, by attaching the gene (called the CAT gene) which codes for the CAT enzyme to it, and observing whether the CAT enzyme is produced. (05 Jan 1998) |
| chloramphenicol acetyltransferase gene | <molecular biology> A gene which codes for the CAT enzyme (the enzyme chloramphenicol acetyltransferase), which helps transfer an acetyl group (a CH3CO- group) to chloramphenicol, an antibiotic. The CAT gene is an important part of CAT assays. (09 Oct 1997) |
| chloramphenicol amidase | <enzyme> Mouse liver microsomal enzyme which cleaves dichloro-acetyl group from chloramphenicol Registry number: EC 3.5.1.- Synonym: chloramphenicol hydrolase. (26 Jun 1999) |
| chloramphenicol o-acetyltransferase | <enzyme> An enzyme that catalyses the acetylation of chloramphenicol to yield chloramphenicol 3-acetate. Since chloramphenicol 3-acetate does not bind to bacterial ribosomes and is not an inhibitor of peptidyltransferase, the enzyme is responsible for the naturally occurring chloramphenicol resistance in bacteria. The enzyme, for which variants are known, is found in both gram-negative and gram-positive bacteria. Chemical name: Acetyl-CoA-chloramphenicol 3-O-acetyltransferase Registry number: EC 2.3.1.28 (12 Dec 1998) |
| chloramphenicol palmitate | <chemical> Same action and use as chloramphenicol. (05 Mar 2000) |
| chloramphenicol resistance | <microbiology, pharmacology> Nonsusceptibility of a bacterium to the action of chloramphenicol, a potent inhibitor of protein synthesis in the 50s ribosomal subunit where amino acids are added to nascent bacterial polypeptides. (12 Dec 1998) |
| chloramphenicol sodium succinate | <chemical> Chloramphenicol-alpha-(sodium succinate);the water-soluble sodium succinate derivative of chloramphenicol, suitable for parenteral administration; antibacterial activity, uses, and side effects are similar to those of the parent compound. (05 Mar 2000) |
| acetyl | <biochemistry, chemistry> This is the radical of acetic acid, it contains a carbonyl and a methyl group that is single-bonded to the carbon, an oxygen is single-bonded to the carbon, and the carbon has two other bonds to the rest of the molecule. (09 Oct 1997) |
| acetyl-activating enzyme | A ligase that catalyses the reaction of acetate and CoA and ATP to form AMP, pyrophosphate, and acetyl-CoA. A key step in the activation of acetate. Synonym: acetate thiokinase, acetate-CoA ligase, acetyl-activating enzyme, acetyl-CoA synthetase. (05 Mar 2000) |
| acetyl chloride | CH3COCl;a colourless liquid used as a reagent; also corrosive, causing severe burns because of hydrolysis to HCl. (05 Mar 2000) |
| acetyl-CoA | <enzyme> Condensation product of coenzyme A and acetic acid, symbolised as CoAS~COCH3; intermediate in transfer of two-carbon fragment, notably in its entrance into the tricarboxylic acid cycle and in fatty acid synthesis. This coenzyme plays a huge role in intermediary metabolism, in which cells synthesise, break down or use nutrient molecules for energy production, growth, etc. Acetyl-coenzyme A synthase is found in bacteria and plants and catalyses the reaction in which acetate enters metabolic pathways and forms acetyl-coenzyme A. Synonym: acetyl-coenzyme A, active acetate. (05 Mar 2000) |
| acetyl-CoA-1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase | <enzyme> Transfers acetate from acetyl CoA to the sn-2-position of 1-alkyl-2-lyso-glycerophosphocholine, forming the substrate for 1-alkylglycerophosphocholine acetyltransferase (EC 2.3.1.67) Registry number: EC 2.3.1.- Synonym: acopc acetyltransferase, 1-alkyl-2-lyso-sn-glycero-3-phosphocholine-acetyl CoA acetyltransferase, alkyllyso-gp-acetyl-CoA acetyltransferase, acetyl-coenzyme a-1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase (26 Jun 1999) |
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