| GnRH | Gonadotropin Releasing Hormone [HP 1898, 2034] = LHRH = Go... |
|---|---|
| AAMT | American Association for Medical Transcription |
| ATF | activating transcription factor; anterior talofibular [ligament]; ascites tumor fluid |
| CTU | cardiac-thoracic unit; centigrade thermal unit; constitutive transcription unit |
| HSTF | heat shock transcription factor; human serum thymus factor |
| STAT | 2/signal transducer and activator of transcription |
|---|---|
| ATF | Activating Transcription Factor |
| ATF1 | Activating transcription factor 1 |
| ATF2 | Activating transcription factor 2 |
| ATF | CRE)/activating transcription factor |
| tactor | A tactile end organ. Origin: L. One who or that which touches (05 Mar 2000) |
|---|---|
| chimeric | 1. Relating to a chimera. Compare: chimera, chimeric molecule. 2. Composed of parts that are of different origin and are seemingly incompatible. (05 Mar 2000) |
| chimeric antibodies | Antibodies that may have the FAB fragment from one species fused with FC fragment from another. (05 Mar 2000) |
| chimeric antibody | <immunology> An antibody that contains polypeptides from different species. (05 Jan 1998) |
| chimeric DNA | <molecular biology> A molecule of DNA that has resulted from recombination, or has resulted from DNA from two sources being spliced together. (05 Jan 1998) |
| chimeric/humanised antibody | <immunology> Genetically engineered combination of a human and mouse antibody. Because a monoclonal antibody is always made with mice cells, it causes an immune response when injected into humans. By replacing the constant regions of a mouse antibody with those of a human antibody, an antibody that binds to an antigen like the original monoclonal antibody, but which is recognised by the human immune system like a human protein, can be manufactured. Alternatively, only those amino acids directly involved in antigen binding are transferred from the mouse antibody into the framework of the human antibody, with a similar result. (05 Jan 1998) |
| chimeric molecule | A molecule (usually a biopolymer) containing sequences derived from two different genes; specifically, from two different species. Compare: chimera. (05 Mar 2000) |
| chimeric proteins | Proteins in individuals that are derived from genetically different zygotes. (12 Dec 1998) |
| reverse transcription | <molecular biology> The process of copying information found in RNA into DNA. (09 Oct 1997) |
| transcription | <molecular biology> Synthesis of RNA by RNA polymerases using a DNA template. (18 Nov 1997) |
| transcription factor | <molecular biology> Protein required for recognition by RNA polymerases of specific stimulatory sequences in eukaryotic genes. Several are known that activate transcription by RNA polymerase II when bound to upstream promoters. Transcription of the 5S RNA gene in Xenopus by RNA polymerase III is dependent on a 40 kD protein TFIIIA that binds to a regulatory site in the centre of the gene and was the first protein found to exhibit the metal binding domains known as zinc fingers. (17 Mar 1998) |
| transcription factor ap-1 | A multiprotein complex composed of the products of c-jun and c-fos proto-oncogenes. These proteins must dimerise in order to bind to the ap-1 recognition site, also known as the tpa-responsive element (tre). Ap-1 controls both basal and inducible transcription of several genes. (12 Dec 1998) |
| transcription factors | Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process. (12 Dec 1998) |
| transcription factor, sp1 | Promoter-specific RNA polymerase II transcription factor that binds to the gc box, one of the upstream promoter elements (upe) in mammalian cells. The binding of sp1 is necessary to initiate transcription in the promoters of a variety of cellular and viral genes including c-ha-ras and HIV. (12 Dec 1998) |
| transcription factors, tfii | The so-called general transcription factors that bind to RNA polymerase II and that are required to initiate transcription. They include tfiia, tfiib, tfiid, tfiie, tfiif, tfiih, tfii-I, and tfiij. In vivo they apparently bind in an ordered multi-step process and/or may form a large preinitiation complex called RNA polymerase II holoenzyme. (12 Dec 1998) |
Á¦Ç°¸í |
ÆÇ¸Å»ç |
º¸ÇèÄÚµå | ¼ººÐ/ÇÔ·® | ±¸ºÐ/º¸Çè±Þ¿© |
|---|
Á¦Ç°¸í |
ÆÇ¸Å»ç |
º¸ÇèÄÚµå | ¼ººÐ/ÇÔ·® | ±¸ºÐ/º¸Çè±Þ¿© |
|---|