| CF | calcaneal fibular [ligament]; calcium leucovorin; calf blood flow; calibration factor; cancer-free; ... |
|---|---|
| F0, | F1 coupling factor |
| H0 | null hypothesis |
| H1 | alternative hypothesis |
| LNH | large number hypothesis |
| E-C coupling | Excitation-contraction coupling |
|---|---|
| (3)H | hypothesis that |
| CF1 | Coupling Factor 1 |
| ECC | Excitation-contraction coupling |
| CI | coupling interval |
| chemiosmotic coupling | The linking of ATP synthesis to electrontransfer by way of an electrochemical hydrogen cation gradient across amembrane. (09 Oct 1997) |
|---|---|
| chemiosmotic hypothesis | <biochemistry, cell biology> A theoretical mechanism (proposed by Mitchell) to explain energy transduction in the mitochondrion. As a general mechanism it is the coupling of one enzyme catalysed reaction to another using the transmembrane flow of an intermediate species. For example Cytochrome oxidase pumps protons across the mitochondrial inner membrane and ATP synthesis is driven by re entry of protons through the ATP synthesising protein complex. The alternative model is production of a chemical intermediate species, but no compound capable of coupling these reactions has ever been identified. (18 Nov 1997) |
| chemiosmotic theory | The theory that the synthesis of ATP (an energy source made and used by the organism) within mitochondria and chloroplasts occurs by way of a proton gradient which forms when electrons are passed through their inner membranes. When protons are then passed through the inner membrane in the opposite direction, energy is released and used to make ATP. (09 Oct 1997) |
| viscous mechanical coupling | <cell biology> Method by which adjacent cilia are synchronised in a field. Coupling is through the transmission of mechanical forces, rather than of a synchronising signal. (18 Nov 1997) |
| metabolic coupling | <cell biology, molecular biology> Transfer between tissue cells in contact of low molecular weight metabolites such as nucleotides and amino acids. Transfer is via channels constituted by the connexons of gap junctions and does not involve exchange with the extracellular medium. First observed in cultures of animal cells in which radio labelled purines were transferred from wild type cells to mutants unable to utilise exogenous purines. (27 Jun 1999) |
| constant coupling | Where several premature beats are seen, the interval between each of them and the preceding normal beat is constant. Synonym: constant coupling. Variable coupling, where several extrasystoles are seen, the interval between each of them and the preceding sinus beat varies. (05 Mar 2000) |
| coupling | <biochemistry> The linking of two independent processes by a common intermediate, for example the coupling of electron transport to oxidative phosphorylation or the ATP ADP conversion to transport processes. (18 Nov 1997) |
| coupling defect | See: familial goiter. (05 Mar 2000) |
| coupling factor | Protein responsible for coupling transmembrane potentials to ATP synthesis in chloroplasts and mitochondria. Include ATP synthesising enzymes (F1 in mitochondrion), that can also act as ATP ases. (18 Nov 1997) |
| coupling factors | Proteins that restore phosphorylating ability to mitochondria that have lost it, i.e., have become "uncoupled" so that oxidation and electron transport no longer produces ATP. Usually termed coupling factor F1, F2, etc. Synonym: C factors. (05 Mar 2000) |
| coupling interval | The interval, usually expressed in hundredths of a second, between a normal sinus beat and the ensuing premature beat. (05 Mar 2000) |
| coupling phase | The physical relationship of two syntenic genes. If they are on the same chromosome, they are said to be "in coupling" or "in the cis phase"; if on opposite members of a chromosome pair, "in repulsion" or "in the trans phase." (05 Mar 2000) |
| signal response coupling | The cascade of processes by which an extracellular signal (typically a hormone or neurotransmitter) interacts with a receptor at the cell surface, causing a change in the level of a second messenger for example calcium or cyclic AMP) and ultimately effects a change in the cells functioning (for example: triggering glucose uptake or initiating cell division). Can also be applied to sensory signal transduction, for example of light at photoreceptors. (18 Nov 1997) |
| stimulus secretion coupling | A term used to describe the events that link receipt of a stimulus with the release of materials from membrane bounded vesicles (the analogy is with excitation contraction coupling in the control of muscle contraction). A classical example is the link between membrane depolarisation at the presynaptic terminal and the release of neurotransmitter into the synaptic cleft. (18 Nov 1997) |
| ionic coupling | <chemistry> The same as electrical coupling. (18 Nov 1997) |
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