| CA | anterior commissure [Lat. commissura anterior]; calcium antagonist; California [rabbit]; cancer; Can... |
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| CARP | carbonic anhydrase-related polypeptide |
| BPTI | basic pancreatic trypsin inhibitor; basic polyvalent trypsin inhibitor; bovine pancreatic trypsin in... |
| PI | first meiotic prophase; isoelectric point; pacing impulse; package insert; pancreatic insufficiency;... |
| ESI | elastase-specific inhibitor; enzyme substrate inhibitor; epidural steroid injection |
| CAI | Carbonic anhydrase inhibitor |
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| CAII | Carbonic Anhydrase II |
| CA | Carbonic anhydrase |
| CAH | Carbonic anhydrase |
| CA B | Carbonic anhydrase B |
| carbonic anhydrase inhibitor | <pharmacology> A group of medications (sulphonamide drugs) which inhibit the enzyme carbonic anhydrase. These medications are used in the treatment of glaucoma. Examples include acetazolamide, dichlorphenamide and methazolamide. (27 Sep 1997) |
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| carbonic anhydrase inhibitors | A class of compounds that reduces the secretion of h+ ions by the proximal kidney tubule through inhibition of carbonic anhydrase (carbonate dehydratase). Although their therapeutic use as diuretics is not frequent, they are used in clinical conditions where alkalinization of the urine is beneficial. Their most frequent application is in the reduction of intra-ocular pressure in the treatment of glaucoma. (12 Dec 1998) |
| carbonic anhydrase II deficiency syndrome | <syndrome> An inherited deficiency of carbonic anhydrase II that results in osteopetrosis and metabolic acidosis. Synonym: osteopetrosis with renal tubular acidosis. (05 Mar 2000) |
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| carbonic acid inhibitor | <pharmacology> A group of diuretic medications which act to inhibit the enzyme carbonic anhydrase to create a metabolic acidosis. Many of these medications are used in the treatment of glaucoma. (27 Sep 1997) |
| anhydrase | <enzyme> An enzyme that catalyses the removal of water from a compound; most such enzymes are now known as hydrases, hydro-lyases, or dehydratases. Carbonic anhydrase, a zinc-containing enzyme that catalyses the interconversion of CO2 with HCO3- and H+. There are at least seven human isozymes that appear predominantly in red blood cells, secretory tissues, muscle, etc. A deficiency of carbonic anhydrase II can result in osteopetrosis and metabolic acidosis. The inhibition of carbonic anhydrase IV and possibly carbonic anhydrase II by sulfonamides is a current therapy in the treatment of glaucoma. Synonym: carbonate dehydratase, carbonate hydro-lyase. (05 Mar 2000) |
| sulfanilazocarbonic anhydrase | <enzyme> Derivative of carbonic anhydrase (EC 4.2.1.1) Registry number: EC 4.2.1.- (26 Jun 1999) |
| carbonic | Relating to carbon. See also under carbonate. (05 Mar 2000) |
| carbonic acid | <chemical> Carbonic acid (h2c03). The hypothetical acid of carbon dioxide and water. It exists only in the form of its salts (carbonates), acid salts (hydrogen carbonates), amines (carbamic acid), and acid chlorides (carbonyl chloride). Chemical name: Carbonic acid (12 Dec 1998) |
| carbonic acid gas | <biochemistry, physiology> A metabolic byproduct of carbohydrate metabolism. Carbon Dioxide collects in the tissues, is cleared by the blood (via the veins) and removed from the body via the lungs when we exhale air. Abbreviation: CO2 (13 Nov 1997) |
| carbonic anhydride | <biochemistry, physiology> A metabolic byproduct of carbohydrate metabolism. Carbon Dioxide collects in the tissues, is cleared by the blood (via the veins) and removed from the body via the lungs when we exhale air. Abbreviation: CO2 (13 Nov 1997) |
| a1-trypsin inhibitor | A glycoprotein that is the major protease inhibitor of human serum, is synthesised in the liver, and is genetically polymorphic due to the presence of over 20 alleles; individuals appropriately homozygous are deficient in a1-trypsin and are predisposed to pulmonary emphysema and juvenile hepatic cirrhosis because of alterations in the amino acid and sialic acid components of the glycoprotein. A1-Antitrypsin also inhibits thrombin. Synonym: a1-trypsin inhibitor, human a1-proteinase inhibitor. (05 Mar 2000) |
| ACE inhibitor | <pharmacology> A group of antihypertensive medications that work by inhibiting an enzyme (angiotensin-converting enzyme) that is important in the regulation of blood pressure. Studies have also indicated that it may help prevent or slow the progression of kidney disease in patients with diabetes. Examples include: captopril, ramipril, enalapril, losartan potassium, bepridil and lisinopril. (12 Mar 1998) |
| aldose reductase inhibitor | <pharmacology> A class of drugs being studied as a way to prevent eye and nerve damage in people with diabetes. Aldose reductase is an enzyme that is normally present in the eye and in many other parts of the body. It helps change glucose (sugar) into a sugar alcohol called sorbitol. Too much sorbitol trapped in eye and nerve cells can damage these cells, leading to retinopathy and neuropathy. Drugs that prevent or slow (inhibit) the action of aldose reductase are being studied as a way to prevent or delay these complications of diabetes. (09 Oct 1997) |
| angiotensin-converting enzyme inhibitor | <pharmacology> A class of drugs used in the treatment of hypertension and heart failure. They exert their haemodynamic effect mainly by inhibiting the renin-angiotensin system and produce a reduction of peripheral arterial resistance. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility. (14 Aug 2000) |
| aromatase inhibitor | Drugs, such as aminoglutethimide, that inhibit aromatase, an enzyme used in the synthesis of oestrogens. (05 Mar 2000) |
| beta-lactamase inhibitor | <pharmacology> Drugs such as clavulanic acid, which are used to inhibit bacterial beta-lactamases; often used with a penicillin or cephalosporin to overcome drug resistance. (05 Mar 2000) |
| Bowman-Birk inhibitor | A polypeptide that will inhibit both trypsin and chymotrypsin. (05 Mar 2000) |
Synonyms : Carboxyanhydrase Inhibitors, Inhibitors, Carbonate Dehydratase, Inhibitors, Carbonic Anhydrase, Inhibitors, Carboxyanhydrase
| carbonic anhydrase inhibitor |
A type of medication used to treat glaucoma. Carbonic anhydrase inhibitors work by reducing the production of aqueous humor, thereby reducing pressure inside the eye.
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