| ¿µ¹® | calcium | ÇÑ±Û | Ä®½· |
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| Ca2+-blocker | calcium channel blocker |
|---|---|
| CCB | calcium channel blocker |
| DHPCCB | dihydropyridine calcium channel blocker |
| NDHPCCB | non-dihydropyridine calcium channel blocker |
| TC | target cell; taurocholate; temperature compensation; teratocarcinoma; tertiary cleavage; tetracyclin... |
| KATP channel | ATP sensitive potassium channel |
|---|---|
| BK channel | K channel |
| CRC | Calcium Release Channel |
| CCA | Calcium channel antagonists |
| CCB | Calcium channel blocker |
channel-shoulder-pin attachment
| calcium channel | <physiology> A membrane channel that is specific for calcium. It is a voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorised as l, t, n, or p types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. (12 May 2002) |
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| calcium channel agonist | <pharmacology> Agents that increase calcium influx into calcium channels of excitable tissues. This causes vasoconstriction in vascular smooth muscle and/or cardiac muscle cells as well as stimulation of insulin release from pancreatic islets. Therefore, tissue-selective calcium agonists have the potential to combat cardiac failure and endocrinological disorders. They have been used primarily in experimental studies in cell and tissue culture. (12 Dec 1998) |
| calcium channel antagonist | <pharmacology> A class of drugs that act by selective inhibition of calcium ion influx through or across cell membranes or on the release and binding of calcium in intracellular pools. Calcium channel blockers are used primarily in the treatment of certain heart conditions and stroke. As they are inducers of vascular and other smooth muscle relaxation, they are also used in the treatment of hypertension and cerebrovascular spasms, as myocardial protective agents, and in the relaxation of uterine spasms. Synonym: calcium antagonist, calcium channel-blocker, slow channel-blocking agent. (12 May 2002) |
| calcium channel-blocker | <pharmacology> A class of drugs that act by selective inhibition of calcium ion influx through or across cell membranes or on the release and binding of calcium in intracellular pools. Calcium channel blockers are used primarily in the treatment of certain heart conditions and stroke. As they are inducers of vascular and other smooth muscle relaxation, they are also used in the treatment of hypertension and cerebrovascular spasms, as myocardial protective agents, and in the relaxation of uterine spasms. Synonym: calcium antagonist, calcium channel-blocker, slow channel-blocking agent. (12 May 2002) |
| ryanodine receptor calcium release channel | Protein complexes that mediate the release of calcium from the sarcoplasmic reticulum in both skeletal and cardiac muscle cells by forming tetrametric complexes. These complexes each then act as a calcium channel. There are three isoforms of the ryr: ryr1, ryr2, and ryr3. Ryr1 is specifically expressed in skeletal muscles and ryr2 in cardiac muscles. Ryr3 is yet another isoform found in non-muscle cells such as neuronal cells. (12 Dec 1998) |
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| gated ion channel | <physiology> Transmembrane proteins of excitable cells, that allow a flux of ions to pass only under defined circumstances. Channels may be either voltage gated, such as the sodium channel of neurons or ligand gated such as the acetylcholine receptor of cholinergic synapses. Channels tend to be relatively ion specific and allow fluxes of typically 1000 ions to pass in around 1ms, they are thus much faster at moving ions across a membrane than transport ATPases. (05 May 1997) |
| voltage-gated channel | A class of ion channel's that open and close in response to change in the electrical potential across the plasma membrane of the cell; voltage-gated Na+ c.'s are important for conducting action potential along nerve cell processes. (05 Mar 2000) |
| voltage gated ion channel | <physiology> A transmembrane ion channel whose permeability to ions is extremely sensitive to the transmembrane potential difference. These channels are essential for neuronal signal transmission and for intracellular signal transduction. See: sodium channel. (18 Nov 1997) |
| channel | A furrow, gutter, or groovelike passageway. See: canal. Origin: L. Canalis (05 Mar 2000) |
| channel forming ionophore | <chemistry> An ionophore that makes an amphipathic pore with hydrophobic exterior and hydrophilic interior. most known types are cation selective. (18 Nov 1997) |
| channel gating | <physiology> Small currents in the membrane just prior to the increase in ionic permeability, due to the movement of charged particles within the membrane. So called because they open the gates for current flow through ion channels. (20 Mar 1998) |
| channel islands | A group of four british islands and several islets in the english channel off the coast of france. They are known to have been occupied prehistorically. They were a part of normandy in 933 but were united to the british crown at the time of the norman conquest in 1066. Guernsey and jersey originated noted breeds of cattle. (12 Dec 1998) |
| channel protein | <chemistry, physiology> A protein that facilitates the diffusion of molecules/ions across lipid membranes by forming a hydrophilic pore. most frequently multimeric with the pore formed by subunit interactions. (18 Nov 1997) |
| channel transport | <radiobiology> In inertial fusion research using light ion drivers, describes the use of current-carrying plasma channels (which are magnetically confined to the channel) to transport electron or ion beams between the ion diode and the fusion target. This allows the ion source to stand back from the target. (09 Oct 1997) |
| chloride channel | Ion channels selective for chloride ions. Various types including ligand activated Cl channels at synapses (the GABA and glycine activated channels), as well as voltage gated Cl channels found in a variety of plant and animal cells. See: CFTR, MDR. (18 Nov 1997) |
| potassium channel | Ion channel selective for potassium ions. There are diverse types with different functions, for example: delayed rectifier channels, M channels, A channels, inward rectifier channels, Ca dependent K channels. (18 Nov 1997) |
| single channel recording | Variant of patch clamp technique. (18 Nov 1997) |
| slow channel-blocking agent | calcium channel-blocking agent |
| sodium channel | <neurology, physiology> The protein responsible for electrical excitability of neurons. A transmembrane ion channel, containing an aqueous pore around 0.4nm diameter, with a negatively charged region internally (the selectivity filter) to block passage of anions. The channel is voltage gated: it opens in response to a small depolarisation of the cell (usually caused by an approaching action potential), by a multistep process. Around 1000 sodium ions pass in the next millisecond, before the channel spontaneously closes (an event with single step kinetics). The channel is then refractory to further depolarisations until returned to near the resting potential. There are around 100 channels per square micron in unmyelinated axons, in myelinated axons, they are concentrated at the nodes of Ranvier. The sodium channel is the target of many of the deadliest neurotoxins. (18 Nov 1997) |
Synonyms : Calcium Channel Agonist, Exogenous Calcium Channel Agonists, Activators, Calcium Channel, Agonist, Calcium Channel, Agonists, Calcium Channel, Channel Activators, Calcium, Channel Agonist, Calcium, Channel Agonists, Calcium
Synonyms : Calcium Channel Blocking Drugs, Exogenous Calcium Antagonists, Exogenous Calcium Blockaders, Exogenous Calcium Inhibitors, Antagonists, Exogenous Calcium, Blockaders, Exogenous Calcium, Blockers, Calcium Channel, Inhibitors, Exogenous Calcium
Synonyms : Calcium Channel, Calcium Channel Antagonist Receptor, Calcium Channel Antagonist Receptors, Calcium Channel Blocker Receptor, Calcium Channel Blocker Receptors, Ion Channel, Calcium, Receptors, Calcium Channel Antagonist, VDCC, Calcium Ion Channel
Synonyms : Dihydropyridine Receptor, L-Type Calcium Channel, L-Type VDCC, L-Type VDCC alpha-2 Subunit, L-Type VDCC beta Subunit, L-Type VDCC delta Subunit, L-Type VDCC gamma Subunit, L-Type Voltage-Dependent Calcium Channels, Calcium Channel, L-Type, L Type VDCC
Synonyms : N-Type Calcium Channel, N-Type VDCC, N-Type Voltage-Dependent Calcium Channels, Calcium Channel, N-Type, Calcium Channels, N Type, Calcium Channels, Neural-Type, Channel, N-Type Calcium, Channels, N-Type Calcium, Channels, Neural-Type Calcium, N Type VDCC
| calcium channel |
a slow voltage-gated protein channel very permeable to calcium ions and slightly permeable to sodium ions, existing in three subtypes designated L, M, and N and located throughout the body; calcium channels are the main cause of action potentials in certain smooth muscles, and the N channels regulate neurotransmitter release.
Ãâó: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
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| calcium channel blocker |
one of a group of drugs that inhibit the entry of calcium into cells or inhibit the mobilization of calcium from intracellular stores, resulting in slowing of atrioventricular and sinoatrial conduction and relaxation of arterial smooth and cardiac muscle; used in the treatment of angina, cardiac arrhythmias, and hypertension.
Ãâó: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
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| calcium channel blocker |
A drug that blocks the entry of calcium into cells, thereby reducing activities that require calcium, such as neurotransmission. Calcium channel blockers are used primarily in the treatment of certain heart conditions but are being studied as potential treatments for Alzheimer
Ãâó: www.alz.org/Resources/Glossary.asp
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| calcium channel blocker |
a medication that lowers blood pressure.
Ãâó: www.health.uab.edu/show.asp
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| calcium channel blocker |
A type of medication that may prevent migraine headaches by acting on the blood vessels, the brain, or both.
Ãâó: www.achenet.org/resources/glossary.php
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