| ¿µ¹® | calcitonin | ÇÑ±Û | Ä®½ÃÅä´Ñ |
|---|---|---|---|
| ¼³¸í | Ä®½·ÀÇ Ã¼³» ³óµµ¸¦ Á¶ÀýÇÏ´Â ±¸½ÇÀ» Çϴ ȣ¸£¸óÀ¸·Î °©»ó»ù¿¡¼ ºÐºñ°¡ µÈ´Ù. Ä®½·ÀÇ Ã¼³» ³óµµÁ¶ÀýÀº Å©°Ô µÎ °¡Áö È£¸£¸ó¿¡ ÀÇÇØ¼ ÀÌ·ç¾îÁø´Ù. Çϳª´Â ºÎ°©»ó»ùÈ£¸£¸ó(parathyroid hormone)·Î ÀÌ È£¸£¸óÀº ü³»ÀÇ Ä®½· ³óµµ¸¦ ³ôÀÌ´Â ¿ªÇÒÀ» ÇÑ´Ù. ¼Òȱ⿡¼ Ä®½·ÀÇ Èí¼ö¸¦ Áõ°¡½ÃŰ°í »À¿¡ ÃàÀûµÇ¾î ÀÖ´Â Ä®½·À» ºÐÇØÇÏ¿© Ç÷ÁßÀ¸·Î ºÐºñÇÏ°Ô Çϰí ÄáÆÏ¿¡¼ Ä®½·ÀÇ ¹èÃâÀ» ¾ïÁ¦ÇÑ´Ù. ¶Ç Çϳª°¡ Ä®½ÃÅä´Ñ(calcitonin)À¸·Î À̰ÍÀº ºÎ°¨»ó»ùÈ£¸£¸óÀÇ ÀÛ¿ëÀ» ¾ïÁ¦ÇÏ¿© Ç÷ÁßÀÇ Ä®½· ³óµµ¸¦ ³·Ãß´Â ¿ªÇÒÀ» ÇÑ´Ù. |
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| ¿µ¹® | enzyme-linked immunoabsorbent assay | ÇÑ±Û | È¿¼Ò¸é¿ªÃøÁ¤¹ý |
|---|---|---|---|
| ¼³¸í | È¿¼Ò°áÇո鿪ÈíÂøÁ¦ °ËÁ¤¹ýÀ¸·Î ¹ø¿ªµÇ°í ÀÖ´Ù. ÀÌ ¹ýÀº Ç׿ø(¶Ç´Â Ç×ü)¿¡ ¾ËÄ®¸® Æ÷½ºÆÄŸ¾ÆÁ¦ ¶Ç´Â Æä¸£¿Á½Ãµð¾ÆÁ¦ µîÀÇ »ê¼Ò¸¦ °áÇÕ½ÃÄÑ µÎ°í ±× »ê¼ÒȰ¼ºÀ» ÁöÇ¥·Î »ï¾Æ Ç׿øÇ×ü¹ÝÀÀÀÇ Á¤µµ¸¦ ¾È ´ÙÀ½ ¿©±â¿¡¼ Ç׿ø(¶Ç´Â Ç×ü)ÀÇ ¾çÀ» ±¸ÇÏ´Â °ÍÀÌ´Ù. ÀÌ ¹ýÀÇ ÀÌÁ¡À¸·Î¼ °í°¨µµ, Á¶ÀÛÀÇ °£´ÜÇÔ ¹× ¹æ»ç¼±¸é¿ªÃøÁ¤¹ýó·³ ¹æ»ç¼º¹°ÁúÀ» »ç¿ëÇÏÁö ¾Ê¾Æµµ µÈ´Ù´Â Á¡À» µé ¼ö ÀÖ´Ù. È£¸£¸óÀ̳ª ¸é¿ª±Û·ÎºÒ¸°ÀÇ Á¤·®¹ýÀ¸·Î¼ ÀÀ¿ë µÇ°í ÀÖÀ¸¸ç ÃøÁ¤¿ë ŰƮµµ ½ÃÆÇµÇ°í ÀÌÀÖ´Ù. |
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| LAI assay | Leukocyte Adherence Inhibition assay |
|---|---|
| ERA | electrical response activity; electroencephalic response audiometry; Electroshock Research Associati... |
| IFA | idiopathic fibrosing alveolitis; immunofluorescence assay; immunofluorescent antibody; incomplete Fr... |
| CGRP | Calcitonin Gene Related Peptide(Protein) |
| CGRPs | Calcitonin Gene-Related Products |
| CGRP | calcitonin-calcitonin gene-related peptide |
|---|---|
| CGRP | AM/calcitonin gene-related peptide |
| alpha-CGRP | Alpha calcitonin gene-related peptide |
| CT | Calcitonin |
| CRLR | Calcitonin Receptor-Like Receptor |
| calcitonin | <protein> A polypeptide hormone produced by C cells of the thyroid that causes a reduction of calcium ions in the blood. (18 Nov 1997) |
|---|---|
| calcitonin gene-related peptide | <protein> A second product transcribed from the calcitonin gene. Calcitonin gene related peptide is found in a number of tissues including nervous tissue. It is a vasodilator that may participate in the cutaneous triple response. It is a neuropeptide of 37 amino acids with structural homology to salmon calcitonin. Co-localises with substance P in neurons. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in neural tissue of the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator. Intracerebral administration leads to a rise in noradrenergic sympathetic outflow, a rise in blood pressure and a fall in gastric secretion. Acronym: CGRP (05 May 2002) |
| receptors, calcitonin | Cell surface proteins that bind calcitonin and trigger intracellular changes which influence the behaviour of cells. Calcitonin receptors outside the nervous system mediate the role of calcitonin in calcium homeostasis. The role of calcitonin receptors in the brain is not well understood. (12 Dec 1998) |
| receptors, calcitonin gene-related peptide | Cell surface proteins that bind calcitonin gene-related peptide (cgrp) with high affinity and trigger intracellular changes which influence the behaviour of cells. Cgrp receptors are present in both the central nervous system and the periphery and are not the same as calcitonin receptors. (12 Dec 1998) |
| acetyl reduction assay | <investigation> A technique for measuring the nitrogen fixation activity in photosynthetic organisms. It uses a flame ionisation detector and a gas chromatography apparatus to determine the reduction of acetylene to ethylene by the enzyme nitrogenase. (06 May 1997) |
| Ames assay | <procedure> One of a number of procedures used to test substances for likely ability to cause cancer that combines the use of animal tissue to generate active metabolites of the substance with a test for mutagenicity in bacteria. (18 Nov 1997) |
| antibiotic assay | <investigation> A test to determine how sensitive a bacterial or fungal strain is to arange of antibiotics bymeasuring the microbes' ability to grow in astandard dilution of each chemical. (09 Oct 1997) |
| assay | <procedure> The determination of the amount of a particular constituent of a mixture or of the biological or pharmacological potency of a drug. (10 May 1997) |
| bandshift assay | <investigation> An assay for proteins, such as transcription factors, that bind specific DNA sequences. A labelled oligonucleotide corresponding to the recognition sequence is incubated with an appropriate nuclear protein extract and run on a nondenaturing acrylamide gel. Oligonucleotides that have been bound by proteins are retarded relative to those that are unbound. (18 Nov 1997) |
| biological assay | <technique> Once a pharmaceutical protein is isolated from the cells in which it was grown, researchers perform tests to measure the protein's biological activity. It must maintain a certain minimal level of biological activity to be used for animal or clinical testing or, later, for market. Researchers also test to confirm that the isolated protein is identical to the desired protein. (21 Mar 1998) |
| radioimmunoprecipitation assay | Sensitive assay using radiolabelled antigens to detect specific antibodies in serum. The antigens are allowed to react with the serum and then precipitated using a special reagent such as protein a sepharose beads. The bound radiolabelled immunoprecipitate is then commonly analyzed by gel electrophoresis. Radioimmunoprecipitation assay (ripa) is often used as a confirmatory test for diagnosing the presence of HIV antibodies. (12 Dec 1998) |
| radioligand assay | <radiobiology> Quantitative determination of receptor (binding) proteins in body fluids or tissue using radioactively labelled binding reagents (e.g., antibodies, intracellular receptors, plasma binders). (12 Dec 1998) |
| radioreceptor assay | A competitive binding assay in which the binder is a membrane or tissue receptor rather than an antibody. (05 Mar 2000) |
| Raji cell radioimmune assay | For immune complexes; a procedure by which immune complexes adsorbed from a test serum by a standard preparation of lymphoblastoid (Raji) cells are assayed by the capacity to bind 125I-labelled antibody to immunoglobulin. (05 Mar 2000) |
| gel retardation assay | A lab technique used to find out if there are proteins binding a fragment of DNA (in a DNA-protein complex) by watching how fast the DNA fragment moves through an electric field and seeing whether it moves slower when a particular protein is also present. (09 Oct 1997) |
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