| DST | 1) Donor Specific Transfusion 2) Dexamethasone Suppression Test |
|---|---|
| CAST | calpastatin; Cardiac Arrhythmia Suppression Trial; Children of Alcoholism Screening Test |
| DST | desensitization test; dexamethasone suppression test; dihydrostreptomycin; disproportionate septal t... |
| HTS | head traumatic syndrome; HeLa tumor suppression; human thyroid-stimulating hormone, human thyroid st... |
| PST | pancreatic suppression test; paroxysmal supraventricular tachycardia; penicillin, streptomycin, and ... |
| CAST | Cardiac Arrhythmia Suppression Trial |
|---|---|
| CISS | Chromosomal in situ suppression |
| CSD | Conditioned Suppression of Drinking |
| DSI | Depolarisation-induced suppression of inhibition |
| DST | Dexamethasone Suppression Test |
| burst | 1. To fly apart or in pieces; of break open; to yield to force or pressure, especially to a sudden and violent exertion of force, or to pressure from within; to explode; as, the boiler had burst; the buds will burst in spring. "From the egg that soon Bursting with kindly rupture, forth disclosed Their callow young." (Milton) Often used figuratively, as of the heart, in reference to a surcharge of passion, grief, desire, etc. "No, no, my heart will burst, an if I speak: And I will speak, that so my heart may burst." (Shak) 2. To exert force or pressure by which something is made suddenly to give way; to break through obstacles or limitations; hence, to appear suddenly and unexpecedly or unaccountably, or to depart in such manner; usually with some qualifying adverb or preposition, as forth, out, away, into, upon, through, etc. "Tears, such as angels weep, burst forth." (Milton) "And now you burst (ah cruel!) from my arms." (Pope) "A resolved villain Whose bowels suddenly burst out." (Shak) "We were the first that ever burst Into that silent sea." (Coleridge) "To burst upon him like an earthquake." (Goldsmith) Origin: OE. Bersten, bresten, AS. Berstan (pers. Sing. Berste, imp. Sing. Baerst, imp. Pl. Burston, p.p. Borsten); akin to D. Bersten, G. Bersten, OHG. Brestan, OS. Brestan, Icel. Bresta, Sw. Brista, Dan. Briste. Cf. Brast, Break. 1. To break or rend by violence, as by an overcharge or by strain or pressure, especially. From within; to force open suddenly; as, to burst a cannon; to burst a blood vessel; to burst open the doors. "My breast I'll burst with straining of my courage." (Shak) 2. To break. "You will not pay for the glasses you have burst?" (Shak) "He burst his lance against the sand below." (Fairfax (Tasso)) 3. To produce as an effect of bursting; as, to burst a hole through the wall. Bursting charge. See Charge. Source: Websters Dictionary (01 Mar 1998) |
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| burst forming unit | <haematology> A bone marrow stem cell lineage detected in culture by its mitotic response to erythropoietin and subsequent erythrocytic differentiation in about 12 mitotic cycles into erythrocytes. (18 Nov 1997) |
| burst number | The number of viral particles that emerge from a cell after a viralinfection has burst it open. (09 Oct 1997) |
| burst size | The number of phages produced by an infected cell. (05 Mar 2000) |
| respiratory burst | <biochemistry> Response of phagocytes to particles (particularly if opsonise d) and to agonists such as formyl peptides and phorbol esters, an enhanced uptake of oxygen leads to the production, by an NADH dependent system, of hydrogen peroxide, superoxide anions and hydroxyl radicals, all of which play a part in bactericidal activity. Defects in the metabolic burst, as in chronic granulomatous disease, predispose to infection particularly with catalase positive bacteria and are usually fatal in childhood. (27 Jun 1999) |
| metabolic burst | <biochemistry> Response of phagocytes to particles (particularly if opsonise d) and to agonists such as formyl peptides and phorbol esters, an enhanced uptake of oxygen leads to the production, by an NADH dependent system, of hydrogen peroxide, superoxide anions and hydroxyl radicals, all of which play a part in bactericidal activity. Defects in the metabolic burst, as in chronic granulomatous disease, predispose to infection particularly with catalase positive bacteria and are usually fatal in childhood. (27 Jun 1999) |
| spider-burst | Radiating dull red capillary lines on the skin of the leg, usually without any visible or palpable varicose veins, but nevertheless due to deep-seated venous dilation; sometimes referred to as skyrocket capillary ectasis. Origin: spiderweb + sunburst (05 Mar 2000) |
| ACTH suppression test | <investigation> A test that measures the response of the adrenal glands to ACTH. In this case, dexamethasone is given to the patient and then blood cortisol levels are measured. Under normal conditions, cortisol levels should drop in response to dexamethasone. In this test one milligram of dexamethasone is administered in the morning and then the blood is drawn for analysis the following morning. Abnormal test results can indicate Cushing's syndrome. (27 Sep 1997) |
| bone marrow suppression | <oncology, pharmacology> A side effect of many anticancer and antiviral drugs, including AZT. Bone marrow suppression leads to a decrease in white blood cells, red blood cells and platelets. Such reductions in turn result in anaemia, bacterial infections and spontaneous or excess bleeding. (09 Oct 1997) |
| growth hormone suppression test | <investigation> A test to determine if growth hormone is suppressed by hyperglycaemia. Growth hormone blood levels are determined sequentially after ingestion of a glucose-rich meal. If growth hormone levels remain elevated (after the glucose is given) then acromegaly or gigantism is suspected. (27 Sep 1997) |
| cortisol suppression test | <investigation> A test that measures the response of the adrenal glands to ACTH. In this case, dexamethasone is given to the patient and then blood cortisol levels are measured. Under normal conditions, cortisol levels should drop in response to dexamethasone. In this test one milligram of dexamethasone is administered in the morning and then the blood is drawn for analysis the following morning. Abnormal test results can indicate Cushing's syndrome. (27 Sep 1997) |
| nonsense suppression | Mutant tRNAs that read a chain termination codon as the signal for incorporation of a specific amino acid residue. (05 Mar 2000) |
| suppression | 1. The act of suppressing, or the state of being suppressed; repression; as, the suppression of a riot, insurrection, or tumult; the suppression of truth, of reports, of evidence, and the like. 2. <medicine> Complete stoppage of a natural secretion or excretion; as, suppression of urine; used in contradiction to retention, which signifies that the secretion or excretion is retained without expulsion. 3. Omission; as, the suppression of a word. Synonym: Overthrow, destruction, concealment, repression, detention, retention, obstruction. Origin: L. Suppressio: cf. F. Suppression. Source: Websters Dictionary (01 Mar 1998) |
| suppression amblyopia | The suppression of the central vision in one eye when the images from the two eyes are so different that they cannot be fused into one. This may be due to: 1) faulty image formation (sensory amblyopia); 2) a large difference in refraction between the two eyes (anisometropic amblyopia); or 3) the two eyes pointing in different directions (strabismic amblyopia). Most suppression amblyopia can be reversed if appropriately treated before age 6 years. Synonym: amblyopia ex anopsia. (05 Mar 2000) |
| suppression, genetic | The restoration of the wild-type phenotype in an organism possessing a mutationally altered genotype. The effects of the mutation may be suppressed by a second "suppressor" mutation on a different gene, by a suppressor mutation on the same gene but located at a distance from the site of the primary mutation, or by the presence of a cytoplasmic suppressor due to a change in non-chromosomal DNA. (12 Dec 1998) |
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