| ¿µ¹® | blast | ÇÑ±Û | ¸ð¼¼Æ÷ |
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| AML | Acute Myelogenous Leukemia Morphologic Classification(FABºÐ·ù) &n... |
|---|---|
| RAEB-T | Refractory Anemia with Excess Blasts in Transformation |
| ATZ | atypical transformation zone |
| ELECTZ | electrosurgical loop excision of the cervical transformation zone |
| HLT | heart-lung transplantation; human lipotropin; human lymphocyte transformation |
| LBT | Lymphocyte blast transformation |
|---|---|
| BC | Blast crisis |
| CML BC | chronic myeloid leukemia in blast crisis |
| BT | Blastic transformation |
| DLT | Direct Linear Transformation |
blastation
| blast transformation | <haematology> The morphological and biochemical changes in lymphocytes, both B and T, on exposure to antigen or to a mitogen. The cells appear to move from G0 to G1 stage of the cell cycle. They usually enlarge and proceed to S phase and mitosis later. The process probably involves receptor cross linking on the plasma membrane. (18 Nov 1997) |
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| blast | 1. <biology, suffix> A suffix or terminal formative, used principally in biological terms, and signifying growth or formation. An immature precursor cell of the type indicated by the preceding word, for example; bioblast, epiblast, mesoblast, etc. 2. A violent gust of wind. A forcible stream of air from an orifice, as from a bellows, the mouth, etc. Hence: The continuous blowing to which one charge of ore or metal is subjected in a furnace; as, to melt so many tons of iron at a blast. 3. The terms hot blast and cold blast are employed to designate whether the current is heated or not heated before entering the furnace. A blast furnace is said to be in blast while it is in operation, and out of blast when not in use. 4. <veterinary> A flatulent disease of sheep. See: blast cell, blastema. Origin: G. Blastos, germ (20 Jun 2000) |
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| blast cell | <haematology> A immature cell of a proliferative compartment in a cell lineage that normally represent up to 5% of the cells in the bone marrow. An over-production of blasts in the marrow is characteristic of leukaemia when the blast cells often spill out into the blood stream. (17 Mar 1998) |
| blast crisis | <haematology> In patients with chronic myelogenous leukaemia, the progression of the diseases to an acute advanced phase, evidenced by an increased number of immature white blood cells in the circulating blood. Sometimes loosely used to describe a rapid increase in the white blood cell count of any leukaemic patient. (17 Mar 1998) |
| blast injuries | Injuries resulting when a person is struck by particles impelled with violent force from an explosion. Blast causes pulmonary concussion and haemorrhage, laceration of other thoracic and abdominal viscera, ruptured ear drums, and minor effects in the central nevous system. (12 Dec 1998) |
| blast injury | Tearing of lung tissue or rupture of abdominal viscera without external injury, as by the force of an explosion. (05 Mar 2000) |
| blast phase | Refers to advanced chronic myelogenous leukaemia. In this phase, the number of immature, abnormal white blood cells in the bone marrow and blood is extremely high. Also called blast crisis. (12 Dec 1998) |
| abiotic transformation | <biochemistry> An abiotic transformation is any process in which a chemical in the environment is altered by non-biological mechanisms (such as by exposure to sunlight). (09 Oct 1997) |
| bacterial transformation | <microbiology> A genetics lab procedure where bacteria are induced to accept and incorporate into their genome foreign pieces of cell-less, isolated DNA, often in the form of a plasmid. The DNA to be introduced usually contains a selectable marker so that the bacteria which successfully incorporate the DNA can be selected for. (09 Oct 1997) |
| genetic transformation | <molecular biology> Genetic change brought about by the introduction of exogenous DNA into a cell. See: transformation, germ line transformation, transfection. (18 Nov 1997) |
| germ line transformation | Micro injection of foreign DNA into an early embryo, so that it becomes incorporated into the germ line of the individual and thus stably inherited in subsequent generations of transgenic organisms. Typically, the DNA would be a reporter gene or cDNA in a vector such as a transposon, that might also carry a visible marker gene such as eye or coat colour), so that successful transformation could readily be detected. (18 Nov 1997) |
| viral transformation | <oncology, virology> Malignant transformation of an animal cell in culture, induced by a virus. (18 Nov 1997) |
| cell transformation | Morphological and physiological changes resulting from infection of an animal cell by an oncogenic virus. (05 Mar 2000) |
| cell transformation, neoplastic | Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill. (12 Dec 1998) |
| cell transformation, viral | An inheritable change in cells manifested by changes in cell division and growth and alterations in cell surface properties. It is induced by infection with a transforming virus. (12 Dec 1998) |
| Haldane transformation | The multiplication of inspired oxygen concentration by the ratio of expired to inspired nitrogen concentrations in the calculation of oxygen consumption or respiratory quotient by the open circuit method. (05 Mar 2000) |
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