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| AML | Acute Myelogenous Leukemia Morphologic Classification(FABºÐ·ù) &n... |
|---|---|
| ILP | inadequate luteal phase; insufficiency of luteal phase; interstitial laser photocoagulation; interst... |
| SPIA | solid-phase immunoabsorption; solid-phase immunoassay |
| LPD | Luteal Phase Defect |
| AP | accessory pathway; accounts payable; acid phosphatase; acinar parenchyma; action potential; active p... |
| BC | Blast crisis |
|---|---|
| LBT | Lymphocyte blast transformation |
| CML BC | chronic myeloid leukemia in blast crisis |
| Phase I | phase |
| S phase | synthesis phase |
blastation
| blast phase | Refers to advanced chronic myelogenous leukaemia. In this phase, the number of immature, abnormal white blood cells in the bone marrow and blood is extremely high. Also called blast crisis. (12 Dec 1998) |
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| blast | 1. <biology, suffix> A suffix or terminal formative, used principally in biological terms, and signifying growth or formation. An immature precursor cell of the type indicated by the preceding word, for example; bioblast, epiblast, mesoblast, etc. 2. A violent gust of wind. A forcible stream of air from an orifice, as from a bellows, the mouth, etc. Hence: The continuous blowing to which one charge of ore or metal is subjected in a furnace; as, to melt so many tons of iron at a blast. 3. The terms hot blast and cold blast are employed to designate whether the current is heated or not heated before entering the furnace. A blast furnace is said to be in blast while it is in operation, and out of blast when not in use. 4. <veterinary> A flatulent disease of sheep. See: blast cell, blastema. Origin: G. Blastos, germ (20 Jun 2000) |
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| blast cell | <haematology> A immature cell of a proliferative compartment in a cell lineage that normally represent up to 5% of the cells in the bone marrow. An over-production of blasts in the marrow is characteristic of leukaemia when the blast cells often spill out into the blood stream. (17 Mar 1998) |
| blast crisis | <haematology> In patients with chronic myelogenous leukaemia, the progression of the diseases to an acute advanced phase, evidenced by an increased number of immature white blood cells in the circulating blood. Sometimes loosely used to describe a rapid increase in the white blood cell count of any leukaemic patient. (17 Mar 1998) |
| blast injuries | Injuries resulting when a person is struck by particles impelled with violent force from an explosion. Blast causes pulmonary concussion and haemorrhage, laceration of other thoracic and abdominal viscera, ruptured ear drums, and minor effects in the central nevous system. (12 Dec 1998) |
| blast injury | Tearing of lung tissue or rupture of abdominal viscera without external injury, as by the force of an explosion. (05 Mar 2000) |
| blast transformation | <haematology> The morphological and biochemical changes in lymphocytes, both B and T, on exposure to antigen or to a mitogen. The cells appear to move from G0 to G1 stage of the cell cycle. They usually enlarge and proceed to S phase and mitosis later. The process probably involves receptor cross linking on the plasma membrane. (18 Nov 1997) |
| accelerated phase of leukaemia | Refers to chronic myelogenous leukaemia that is progressing. The number of immature, abnormal white blood cells in the bone marrow and blood is higher than in the chronic phase, but not as high as in the blast phase. (12 Dec 1998) |
| acceleration phase | <cell biology, cell culture> A period of increasing growth before the log phase in a culture of microbes. After the culture is started on a medium, at first there is no growth (the lag phase) and then the microbes start to gradually grow (acceleration phase) until they reach a constant maximum rate of growth (log phase). (15 Jan 1998) |
| acute-phase protein | <haematology> These plasma proteins (in addition to fibrinogen) increase 25% or more in response to inflammation and injury are under direct control of interleukin-6 (IL-6) (hepatocyte-stimulating factor). Other proteins which increase are ceruloplasmin, C3 and C4 which increase 50% or more; alpha-1 acid glycoprotein, alpha-1 antitrypsin, haptoglobin and fibrinogen (the major determinant of viscosity 1 ) which increase two- to fourfold; C-reactive protein (CRP) and serum amyloid A which increase several hundred-fold. Despite long-held clinical opinion to the contrary, available data indicate that neither ESR nor measurement of specific acute-phase reactants are useful in excluding underlying infection or inflammation regardless of the pretest probability. These proteins are secreted into the blood in increased or decreased quantities by hepatocytes in response to trauma, inflammation, or disease. They can serve as inhibitors or mediators of the inflammatory processes. Certain acute-phase proteins have been used to diagnose and follow the course of diseases or as tumour markers. See also: amyloid, c-reactive protein, erythrocyte sedimentation rate, viscosity. (25 Jun 1999) |
| acute-phase reaction | <immunology, rheumatology> Refers to the changes in synthesis of certain proteins within the serum during an inflammatory response, which provides rapid protection for the host against microorganisms via non-specific defense mechanisms. It consists of fever, an increase in inflammatory humoral factors, and an increased synthesis by hepatocytes of a number of proteins or glycoproteins usually found in the plasma; the reaction is mediated by endogenous pyrogens, the hypothalamus, adrenal hormones, and other factors. (12 Jul 2000) |
| anal phase | In psychoanalytic personality theory, the stage of psychosexual development, occurring when a child is between 1 and 3 years, during which activities, interests, and concerns are centreed around the anal zone. (05 Mar 2000) |
| aqueous phase | The water portion of a system consisting of two liquid phase's, one mainly water, the other a liquid immiscible with water (e.g., benzene, ether). (05 Mar 2000) |
| g0 phase | Phase of the cell cycle where cells exist in a quiescent state. These cells have unduplicated DNA, degraded RNA and protein, and low enzyme activity. The ability to switch between g0 and g1 (and vice versa) determines the post-embryonic cell proliferation rate and is defectively controlled in neoplastic cells. (12 Dec 1998) |
| g1 phase | <cell biology, molecular biology> The period during interphase in the cell cycle between mitosis and the S phase (when DNA is replicated). Also known as the decision period of the cell, because the cell decides to divide when it enters the s phase. The G stands for gap. (09 Oct 1997) |
| g2 phase | <cell biology, molecular biology> The period during interphase in the cell cycle between the S phase (when DNA is replicated) and mitosis (when the nucleus, then cell, divides). at this time, the cell checks the accuracy of DNA replication and prepares for mitosis. The G stands for gap. (09 Oct 1997) |
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