| 영문 | bilirubin | 한글 | 빌리루빈 |
|---|---|---|---|
| 설명 | 담즙의 주성분으로서 혈색소에서 유래하지만 철을 포함하지는 않는다. 생성되는 곳은 주로 지라, 골수 등의 망내계로, 빌리베르딘을 거쳐 유리형의 빌리루빈으로서 혈중으로 방출된다. 85%는 노화 적혈구의 혈색소에서 유래한다. 유리형 빌리루빈은 물에 녹지 않는다. 혈중에서는 알부민과 결합해 있으며 콩팥에서 배설되지 않으며, 또 신경조직으로의 친화성이 커 알부민과 결합하지 않은 것은 신경독성을 갖는다. 모든 조직과 체액에 분포하며, 간과 콩팥에서 빌리루빈 침착이 현저하다. |
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| ADME | [drug] absorption, distribution, metabolism, and excretion |
|---|---|
| BM | Bachelor of Medicine; barium meal; basal medium; basal metabolism; basement membrane; basilar membra... |
| CMI | carbohydrate metabolism index; care management integration; case mix index; cell-mediated immunity; ... |
| DIM | divalent ion metabolism; medium infective dose [Lat. dosis infectionis media] |
| EMR | educable mentally retarded; electromagnetic radiation; electronic medical record; emergency mechanic... |
| ADME | Absorption, distribution, metabolism, and excretion |
|---|---|
| CAM | Crassulacean Acid Metabolism |
| FPM | First pass metabolism |
| IEM | Inborn Errors of Metabolism |
| rCMRGlc | Regional cerebral glucose metabolism |
| bilirubin | <biochemistry> A pigment produced when the liver processes waste products. A high bilirubin level causes yellowing of the skin. (16 Dec 1997) |
|---|---|
| bilirubin encephalopathy | <paediatrics> Disorder due to jaundice in a newborn baby with high blood levels of the pigment bilirubin that is deposited in the brain resulting in damage. The level of bilirubin is monitored in newborns to determine whether treatment is needed to prevent kernicterus. With brain affected, it is also called bilirubin encephalopathy. (12 Dec 1998) |
| bilirubin glucuronoside glucuronosyltransferase | <enzyme> Conjugates one or two glucuronic acid molecules to the carboxyl groups of the propionate side chains of bilirubin thereby removing free bilirubin from the body; ugt1.4 is the minor human bilirubin udp-glucuronosyltransferase (ugt) Registry number: EC 2.4.1.95 Synonym: bilirubin glucuronyl transferase, bilirubin glucuronyltransferase, bilirubin udp-glucuronosyltransferase, ugt1.4 (26 Jun 1999) |
| bilirubin monoglucuronide transglucuronidase | <enzyme> Is a transferase that transfers a glucuronoside from one molecule of bilirubin glucuronoside to another, forming bilirubin bisglucuronoside and unconjugated bilirubin. A step in haem catabolism. (05 May 2002) |
| bilirubin UDP-glucuronyltransferase | <enzyme> An enzyme that catalyses the reaction of UDP-glucuronate and bilirubin forming UDP and bilirubin-glucuronoside; a deficiency of this enzyme is associated with Crigler-Najjar syndrome. (05 Mar 2000) |
| conjugated bilirubin | Conjugated bilirubin = Direct bilirubin. Bilirubin that has been chemically attached to a glucuronide in the liver. The bilirubin that is excreted into the bile by the liver and stored in the gallbladder or transferred to the duodenum. Normal direct bilirubin is 0 to 0.3 mg/dl. Greater than normal values can be seen in bile duct obstruction, cirrhosis, Crigler-Najjar syndrome, Dubin-Johnson syndrome and hepatitis. (27 Sep 1997) |
| delta bilirubin | The fraction of bilirubin covalently bound to albumin; in conventional methods it is measured as part of conjugated bilirubin. Because of its covalent bond during the recovery phase of hepatocellular jaundice, it may persist in the blood for a week or more after urine clears. (05 Mar 2000) |
| direct bilirubin | Conjugated bilirubin = Direct bilirubin. Bilirubin that has been chemically attached to a glucuronide in the liver. The bilirubin that is excreted into the bile by the liver and stored in the gallbladder or transferred to the duodenum. Normal direct bilirubin is 0 to 0.3 mg/dl. Greater than normal values can be seen in bile duct obstruction, cirrhosis, Crigler-Najjar syndrome, Dubin-Johnson syndrome and hepatitis. (27 Sep 1997) |
| direct reacting bilirubin | The fraction of serum bilirubin which has been conjugated with glucuronic acid in the liver cell to form bilirubin diglucuronide; so called because it reacts directly with the Ehrlich diazo reagent; increased levels are found in hepatobiliary diseases, especially of the obstructive variety. Synonym: conjugated bilirubin. (05 Mar 2000) |
| indirect bilirubin | <biochemistry> Free bilirubin that has not been attached to a glucuronide molecule. This results from the rapid breakdown of red blood cells. The haemoglobin molecule is normally converted to bilirubin. Greater than normal values of indirect bilirubin can be seen in erythroblastosis foetalis, haemolytic anaemia, sickle cell anaemia, transfusion reactions, pernicious anaemia and resolution of large haematomas. (27 Sep 1997) |
| indirect reacting bilirubin | The fraction of serum bilirubin which has not been conjugated with glucuronic acid in the liver cell; so called because it reacts with the Ehrlich diazo reagent only when alcohol is added; increased levels are found in hepatic disease and haemolytic conditions. Synonym: unconjugated bilirubin. (05 Mar 2000) |
| UDPglucuronate-bilirubin glucuronosyltransferase | Hepatic transferases that catalyze the transfer of the glucuronic moiety of UDP-glucuronic acid to bilirubin or bilirubin glucuronide, thus producing UDP and either bilirubin-glucoronoside or bilirubin bisglucuronoside, respectively; these bile conjugates are then secreted into the bile. Synonym: UDPglucuronate-bilirubinglucuronoside glucuronosyltransferase. (05 Mar 2000) |
| unconjugated bilirubin | <biochemistry> Free bilirubin that has not been attached to a glucuronide molecule. This results from the rapid breakdown of red blood cells. The haemoglobin molecule is normally converted to bilirubin. Greater than normal values of indirect bilirubin can be seen in erythroblastosis foetalis, haemolytic anaemia, sickle cell anaemia, transfusion reactions, pernicious anaemia and resolution of large haematomas. (27 Sep 1997) |
| basal metabolism | <biochemistry, biology> Heat production, or its measurement, of an organism at the lowest level of cell chemistry in an inactive, awake, fasting state. It may be determined directly by means of a calorimeter or indirectly by calculating the heat production from an analysis of the end products of oxidation within the organism or from the amount of oxygen utilised. (27 Jun 1999) |
| calcium metabolism | A set of biochemical processes which act to keep the level of calcium in the blood at a constant level, with enough around to build bones and teeth. (09 Oct 1997) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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