| BIG 6 | analysis of 6 serum components |
|---|---|
| PRA | 1) Plasma Renin Activity 2) Phospho-Ribosyl-Amine |
| RAA | Renin-Angiotensin-Aldosterone |
| ARC | accelerating rate calorimetry; acquired immunodeficiency syndrome-related complex; active renin conc... |
| HREH | high-renin essential hypertension |
| BIG-ET | BIG-endothelin |
|---|---|
| Big ET-1 | Big endothelin-1 |
| BET1 | big endothelin 1 |
| AR | Active renin |
| LREH | Low-renin essential hypertension |
| big | 1. Having largeness of size; of much bulk or magnitude; of great size; large. "He's too big to go in there." 2. Great with young; pregnant; swelling; ready to give birth or produce; often figuratively. "[Day] big with the fate of Cato and of Rome." (Addison) 3. Having greatness, fullness, importance, inflation, distention, etc, whether in a good or a bad sense; as, a big heart; a big voice; big looks; to look big. As applied to looks, it indicates haughtiness or pride. "God hath not in heaven a bigger argument." (Jer. Taylor) Big is often used in self-explaining compounds; as, big-boned; big-sounding; big-named; big-voiced. To talk big, to talk loudly, arrogantly, or pretentiously. "I talked big to them at first." (De Foe) Synonym: Bulky, large, great, massive, gross. Origin: Perh. From Celtic; cf. W. Beichiog, beichiawg, pregnant, with child, fr. Baich burden, Arm. Beac'h; or cf. OE. Bygly, Icel. Biggiligr, (properly) habitable; (then) magnigicent, excellent, fr. OE. Biggen, Icel. Byggja, to dwell, build, akin to E. Be. Source: Websters Dictionary (01 Mar 1998) |
|---|---|
| big axillary nodes and normal breasts | <radiology> Consider: lymphoma, leukaemia, rheumatoid arthritis (12 Dec 1998) |
| big brain | <molecular biology> Neurogenic gene of Drosophila, believed to encode a product involved in cell cell communication, perhaps via gap junctions. Member of the major intrinsic protein family. (18 Nov 1997) |
| big-head | 1. In horses, usually denotes osteodystrophia fibrosa. 2. Gas gangrene infection of tissues of the head, caused by Clostridium novyi in sheep, usually young rams with head wounds. 3. Photosensitization in sheep. 4. An acute disease of young rams caused by the Clostridium novyi, C. Sordellii or, rarely, C. Chauvoei and characterised by a nongaseous, nonhemorrhagic, edematous swelling of the head and neck. (05 Mar 2000) |
| renin | <enzyme> An enzyme of the hydrolase class that catalyses cleavage of the leucine leucine bond in angiotensin to generate angiotensin. 1. The enzyme is synthesised as inactive prorenin in the kidney and released into the blood in the active form in response to various metabolic stimuli. Not to be confused with rennin (chymosin). (25 Jun 1999) |
| renin-angiotensin-aldosterone system | The hormones, renin, angiotensin, and aldosterone work together to regulate blood pressure. A sustained fall in blood pressure causes the kidney to release renin. This is converted to angiotensin in the circulation. Angiotensin then raises blood pressure directly by arteriolar constriction and stimulates adrenal gland to produce aldosterone which promotes sodium and water retention by kidney, such that blood volume and blood pressure increase. (05 Mar 2000) |
| renin-angiotensin system | <physiology> A system consisting of renin, angiotensin-converting enzyme, and angiotensin II. Renin, an enzyme produced in the kidney, acts on angiotensinogen, an alpha-2 globulin produced by the liver, forming angiotensin I. The converting enzyme contained in the lung acts on angiotensin I in the plasma converting it to angiotensin II, the most powerful directly pressor substance known. It causes contraction of the arteriolar smooth muscle and has other indirect actions mediated through the adrenal cortex. (25 Jun 1999) |
| plasma renin activity | The estimation of renin in plasma by measuring the rate of formation of angiotensin I or II. (05 Mar 2000) |
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