| BIG 6 | analysis of 6 serum components |
|---|---|
| ACTH | Adreno-Cortico-Tropic(=Tropin)(or steroid) Hormone |
| ACTH | adrenocorticotropic hormone |
| ACTH-LI | adrenocorticotropin-like immunoreactivity |
| ACTH-RF | adrenocorticotropic hormone releasing factor |
| BIG-ET | BIG-endothelin |
|---|---|
| Big ET-1 | Big endothelin-1 |
| ACTH-R | ACTH receptor |
| IR-ACTH | Immunoreactive ACTH |
| BET1 | big endothelin 1 |
| big | 1. Having largeness of size; of much bulk or magnitude; of great size; large. "He's too big to go in there." 2. Great with young; pregnant; swelling; ready to give birth or produce; often figuratively. "[Day] big with the fate of Cato and of Rome." (Addison) 3. Having greatness, fullness, importance, inflation, distention, etc, whether in a good or a bad sense; as, a big heart; a big voice; big looks; to look big. As applied to looks, it indicates haughtiness or pride. "God hath not in heaven a bigger argument." (Jer. Taylor) Big is often used in self-explaining compounds; as, big-boned; big-sounding; big-named; big-voiced. To talk big, to talk loudly, arrogantly, or pretentiously. "I talked big to them at first." (De Foe) Synonym: Bulky, large, great, massive, gross. Origin: Perh. From Celtic; cf. W. Beichiog, beichiawg, pregnant, with child, fr. Baich burden, Arm. Beac'h; or cf. OE. Bygly, Icel. Biggiligr, (properly) habitable; (then) magnigicent, excellent, fr. OE. Biggen, Icel. Byggja, to dwell, build, akin to E. Be. Source: Websters Dictionary (01 Mar 1998) |
|---|---|
| big axillary nodes and normal breasts | <radiology> Consider: lymphoma, leukaemia, rheumatoid arthritis (12 Dec 1998) |
| big brain | <molecular biology> Neurogenic gene of Drosophila, believed to encode a product involved in cell cell communication, perhaps via gap junctions. Member of the major intrinsic protein family. (18 Nov 1997) |
| big-head | 1. In horses, usually denotes osteodystrophia fibrosa. 2. Gas gangrene infection of tissues of the head, caused by Clostridium novyi in sheep, usually young rams with head wounds. 3. Photosensitization in sheep. 4. An acute disease of young rams caused by the Clostridium novyi, C. Sordellii or, rarely, C. Chauvoei and characterised by a nongaseous, nonhemorrhagic, edematous swelling of the head and neck. (05 Mar 2000) |
| ACTH | <endocrinology> A peptide hormone that is produced by the anterior pituitary gland. It stimulates the adrenal cortex to secrete glucocorticoid hormones, which help cells synthesise glucose, catabolize proteins, mobilizefree fatty acids and inhibit inflammation in allergic responses. (10 May 1997) |
| ACTH-producing adenoma | <tumour> A pituitary tumour composed of corticotrophs that produce ACTH, often a basophilic adenoma; may give rise to Cushing's disease or Nelson's syndrome. (05 Mar 2000) |
| ACTH stimulation test | A test for adrenal cortical function; ACTH administered by continuous intravenous infusion, or intramuscularly, evokes an increase in plasma cortisol in normal persons; in adrenal cortical insufficiency, the expected increase in plasma cortisol is limited or nonexistent. (05 Mar 2000) |
| ACTH suppression test | <investigation> A test that measures the response of the adrenal glands to ACTH. In this case, dexamethasone is given to the patient and then blood cortisol levels are measured. Under normal conditions, cortisol levels should drop in response to dexamethasone. In this test one milligram of dexamethasone is administered in the morning and then the blood is drawn for analysis the following morning. Abnormal test results can indicate Cushing's syndrome. (27 Sep 1997) |
| acth syndrome, ectopic | Symptom complex due to acth production by non-pituitary neoplasms. (12 Dec 1998) |
| ectopic ACTH syndrome | <syndrome> The association of Cushing's syndrome with a non-pituitary neoplasm, usually a lung carcinoma that produces ACTH. (05 Mar 2000) |
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