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HBDT human basophil degranulation test
MCD magnetic circular dichroism; mast-cell degranulation; mean cell diameter; mean of consecutive differ...
ABC absolute basophil count; absolute bone conduction; acalculous biliary colic; acid balance control; a...
bas basilar; basophil, basophilic
baso basophil
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BDT Basophil Degranulation Test
HBDT Human Basophil Degranulation Test
CBH Cutaneous basophil hypersensitivity
RBL Rat basophil leukaemia
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basophil degranulation test An in vitro test used in the diagnosis of allergies including drug hypersensitivity. The allergen is added to the patient's white blood cells and the subsequent histamine release is measured.
(12 Dec 1998)
cell degranulation The process of losing cytoplasmic granules. This occurs in mast cells, basophils, neutrophils, eosinophils, and platelets when secretory products are released from the granules.
(12 Dec 1998)
degranulation Release of secretory granule contents by fusion with the plasma membrane.
(18 Nov 1997)
adenoma, basophil A small tumour of the anterior lobe of the pituitary gland whose cells stain with basic dyes. It may give rise to excessive secretion of acth, resulting in cushing's syndrome.
(12 Dec 1998)
basophil <haematology> Mammalian granulocyte with large heterochromatic basophilic granules that contain histamine bound to a protein and heparin like mucopolysaccharide matrix. They are not phagocytic. Very similar to mast cells though it is not clear whether they have common lineage.
(18 Nov 1997)
basophil adenoma <tumour> A tumour of the adenohypophysis in which the cell cytoplasm stains with basic dyes, often ACTH producing.
(05 Mar 2000)
basophil cell of anterior lobe of hypophysis beta cell of anterior lobe of hypophysis
basophil granule A granule that stains readily with a basic dye.
(05 Mar 2000)
basophil substance The material consisting of granular endoplasmic reticulum and ribosomes that occurs in nerve cell bodies and dendrites.
Synonym: basophil substance, basophilic substance, chromophil substance, Nissl bodies, Nissl granules, substantia basophilia, tigroid bodies, tigroid substance.
(05 Mar 2000)
tissue basophil <cell biology, immunology> Resident cell of connective tissue that contains many granules rich in histamine and heparan sulphate.
Release of histamine from mast cells is responsible for the immediate reddening of the skin in a weal and flare response. Very similar to basophils and possibly derived from the same stem cells.
Two types of mast cells are now recognised, those from connective tissue and a distinct set of mucosal mast cells, the activities of the latter are T-cell dependent.
(05 Jan 1998)
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