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bacteriophage <microbiology, virology> Viruses that have a specific affinity for and infect bacteria.
The bacteriophages that attack Escherichia coli are termed coliphages, examples of these are lambda phage and the T even phages, T2, T4 and T6. Basically, phages consist of a protein coat or capsid enclosing the genetic material, DNA or RNA, that is injected into the bacterium upon infection. In the case of virulent phages all synthesis of host DNA, RNA and proteins ceases and the phage genome is used to direct the synthesis of phage nucleic acids and proteins using the host's transcriptional and translational apparatus.
These phage components then self assemble to form new phage particles. The synthesis of a phage lysozyme leads to rupture of the bacterial cell wall releasing, typically 100-200 phage progeny.
The temperate phages, such as lambda, may also show this lytic cycle when they infect a cell, but more frequently they induce lysogeny.
The study of bacteriophages has been important for our understanding of gene structure and regulation. Lambda has been extensively used as a vector in recombinant DNA studies.
(15 Nov 1997)
bacteriophage 2 depolymerase <enzyme> Hydrolyzes glycolipoproteins and lipopolysaccharides; releases aminosugars
Registry number: EC 3.2.1.-
Synonym: phage 2 depolymerase
(26 Jun 1999)
bacteriophage immunity The state induced in a bacterium by lysogenization, the lysogenic bacterium being insusceptible to further lysogenization or to a lytic cycle by a superinfecting bacteriophage, in contradistinction to bacteriophage resistance.
(05 Mar 2000)
bacteriophage lambda <microbiology, virology> A bacteriophage, or virus which infects bacteria, that infects E. Coli. It has a complex set of regulatory mechanisms to determine whether it will quietly insert its DNA into the bacterial genome to become dormant and to be reproduced whenever the bacterium reproduces (to lysogenize), or whether it will hijack the bacterium's cellular machinery to reproduce itself and prepare to infect more bacteria, causing the bacterium to self-destruct shortly after infection (to lyse).
Lambda is particularly useful to geneticists because parts of it can be used to introduce foreign DNA into the bacterial genome, it is a cloning vector.
(09 Oct 1997)
bacteriophage m13 <microbiology> A bacteriophage (a virus which infects bacteria) that has single-stranded DNA. It is used as a method of obtaining single strands of foreign DNA so that the foreign DNA can be sequenced (that is, the order of its nucleotide bases can be determined). It is also used in procedures to create mutations in vitro (in a test tube rather than within an organism).
(09 Oct 1997)
bacteriophage mu An unassigned species of temperate coliphage, in the family myoviridae, composed of a linear, double-stranded molecule of DNA, which is able to insert itself at random at any point on the host chromosome. It frequently causes a mutation by interrupting the continuity of the bacterial operon at the site of insertion.
(12 Dec 1998)
bacteriophage omicron x174 <microbiology> A bacteriophage (a virus that infects bacteria) which has as its genetic material DNA in single strands instead of the usual double strands. The virus is useful to those who study how DNA replicates.
(09 Oct 1997)
bacteriophage p1 An unassigned species of temperate bacteriophage in the family myoviridae which infects e. Coli. It is the largest of the coliphages and consists of double-stranded DNA, terminally redundant, and circularly permuted.
(12 Dec 1998)
bacteriophage p2 An unassigned species of temperate bacteriophage in the family myoviridae which infects e. Coli. It consists of linear double-stranded DNA with 19-base sticky ends.
(12 Dec 1998)
bacteriophage p22 An unassigned species of temperate bacteriophage in the family podoviridae that infects salmonella species. The genome consists of double-stranded DNA, terminally redundant, and circularly permuted.
(12 Dec 1998)
bacteriophage phi 6 Virulent bacteriophage and sole member of the genus cystovirus that infects pseudomonas species. The virion has a segmented genome consisting of three pieces of doubled-stranded DNA and also contains a unique lipid-containing membrane.
(12 Dec 1998)
bacteriophage phi x 174 The type species of the genus microvirus. A prototype of the small virulent DNA coliphages, it is composed of a single strand of supercoiled circular DNA, which on infection, is converted to a double-stranded replicative form by a host enzyme.
(12 Dec 1998)
bacteriophage plaque A clear circular zone in an otherwise confluent growth of bacteria on an agar surface resulting from bacterial lysis by bacterial viruses.
(05 Mar 2000)
bacteriophage resistance Resistance of a bacterial mutant to infection by a bacteriophage to which the parent (wild type) strain is susceptible.
(05 Mar 2000)
bacteriophage t3 Bacteriophage in the genus t7-like phages, of the family podoviridae, which is very closely related to bacteriophage t7.
(12 Dec 1998)
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R17 bacteriophage Bacteriophage with RNA genome that codes for the enzyme RNA synthetase and for the coat protein, a protein to which the RNA is attached and that is involved in attachment to the bacterium.
(18 Nov 1997)
vegetative bacteriophage The form of bacteriophage in which the bacteriophage nucleic acid (lacking its coat) multiplies freely within the host bacterium, independently of bacterial multiplication.
(05 Mar 2000)
mature bacteriophage The complete, infective form of bacteriophage.
(05 Mar 2000)
virulent bacteriophage A bacteriophage that regularly causes lysis of the bacteria that it infects; it may exist in one or the other of only two forms, vegetative or mature; it does not have a probacteriophage form (i.e., its genome does not incorporate with that of the host bacterium), therefore it does not effect lysogenization.
(05 Mar 2000)
defective bacteriophage A temperate bacteriophage mutant whose genome does not contain all of the normal components and cannot become fully infectious virus, yet can replicate indefinitely in the bacterial genome as defective probacteriophage; many defective bacteriophage's are mediators of transduction.
Synonym: defective phage.
(05 Mar 2000)
temperate bacteriophage Bacteriophage whose genome incorporates with, and replicates with, that of the host bacterium; dissociation (and resultant development of vegetative bacteriophage) occurs at a slow rate resulting occasionally in lysis of a bacterium and release of mature bacteriophage, thus rendering the bacterial culture capable of inducing general lysis if transferred to a culture of a susceptible bacterial strain.
(05 Mar 2000)
typhoid bacteriophage Bacteriophage specific for Salmonella typhi.
(05 Mar 2000)
filamentous bacteriophage <molecular biology> A type of single-stranded DNA bacteriophage (virus which infects bacteria) that has a capsid which is long and thin, like a filament.
Examples include the viruses F1 and M13.
(10 Mar 1998)
lambda bacteriophage <virology> Bacterial DNA virus, first isolated from E. Coli. Its structure is similar to that of the T even phages.
Lambda genetic material consists of a double-stranded DNA molecule with 5' twelve-base-pair sticky ends, known as cos sites, which permit circularisation of the DNA molecule. It shows a lytic cycle and a lysogenic cycle and studies on the control of these alternative cycles have been very important for our understanding of the regulation of gene transcription.
It is used as a cloning vector, accommodating fragments of DNA up to 15 kilobase pairs long. For larger pieces, the cosmid vector was constructed from its ends.
(14 Mar 2000)
lysosogenic bacteriophage <virology> Bacteriophage that can take part in a lysogenic or lytic cycle in its bacterial host.
See: lysogeny.
(15 Oct 1997)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 1
  • Bacteriophage HK022 - »õâ A tentative species in the genus lambda-like viruses, family SIPHOVIRIDAE.
    Synonyms : HK022, Bacteriophage, HK022, Enterobacteria phage
  • Bacteriophage IKe - »õâ A species of filamentous phage in the genus INOVIRUS, family INOVIRIDAE. They are specific for enterobacteria that contain an IncN plasmid.
    Synonyms : IKe Phages, Phage, IKe, Phages, IKe
  • Bacteriophage lambda - »õâ A temperate inducible phage and type species of the genus lambda-like viruses, in the family SIPHOVIRIDAE. Its natural host is E. coli K12. Its VIRION contains linear double-stranded DNA with single-stranded 12-base 5' sticky ends. The DNA circularizes on infection.
    Synonyms :
  • Bacteriophage M13 - »õâ Temperate bacteriophage of the genus INOVIRUS which infects enterobacteria, especially E. coli. It is a filamentous phage consisting of single-stranded DNA and is circularly permuted.
    Synonyms : M13 Phages, M13, Coliphage, Phage, M13, Phage, fd, Phages, M13, Phages, fd, fd Phages
  • Bacteriophage mu - »õâ A temperate coliphage, in the genus Mu-like viruses, family MYOVIRIDAE, composed of a linear, double-stranded molecule of DNA, which is able to insert itself randomly at any point on the host chromosome. It frequently causes a mutation by interrupting the continuity of the bacterial OPERON at the site of insertion.
    Synonyms : mu Phages
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bacteriophage a virus that is parasitic in bacteria; "phage uses the bacterium's machinery and energy to produce more phage until the bacterium is destroyed and phage is released to invade surrounding bacteria"
Ãâó: wordnet.princeton.edu/perl/webwn
bacteriophage A phage (also called bacteriophage) (in Greek phageton = food/consumption) is a small virus that infects only bacteria. Like viruses that infect eukaryotes, phages consist of an outer protein hull and the enclosed genetic material (which consists of double-stranded DNA in 95% of the phages known) of 5 to 650 kbp (kilo base pairs) with a length of 24 to 200 nm. The vast majority of phages (95%) have a tail to let them inject their genetic material into the host. ...
Ãâó: en.wikipedia.org/wiki/Bacteriophage
bacteriophage Viruses that infect cells. If alien genes are intergrated into that DNA, it invades into the host cell when in infection and multiplies in the form of viruses.
Ãâó: library.thinkquest.org/28920/eng/wordlist.html
bacteriophage A virus that infects and replicates in bacteria. These are either lytic viruses, which always kill the host, or temperate viruses, which can either lyse the host cell or establish a stable relationship in which the bacteriophage genome is stably maintained in the host genome (see also lysogen).
Ãâó: www.nature.com/nrg/journal/v4/n6/glossary/nrg1087_...
bacteriophage An ultra-microscopic organism, similar to a virus, that replicates in bacteria, causing lysis of cells.
Ãâó: www.pestmanagement.co.uk/lib/glossary/glossary_b.s...
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