| DSPN | distal sensory polyneuropathy; distal symmetrical polyneuropathy |
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| AA | abdominal aorta; acetic acid; achievement age; active alcoholic; active assistive [range of motion];... |
| AT | abdominal thrusts; achievement test; Achilles tendon; Achard-Thiers [syndrome]; adaptive thermogenes... |
| DAI | diffuse axonal injury |
| FAP | Familial Amyloid Polyneuropathy |
| AMAN | Acute Motor Axonal Neuropathy |
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| AI | Axonal injury |
| DAI | Diffuse Axonal Injury |
| GAN | Giant Axonal Neuropathy |
| GAD | Gracile axonal dystrophy |
| axonal polyneuropathy | A type of polyneuropathy in which axon degeneration is the sole/predominant feature; many aetiologies, particularly toxic and metabolic; on nerve conduction studies, affects amplitudes of the responses, but does not cause conduction slowing or block. Synonym: axonal polyneuropathy. (05 Mar 2000) |
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| axonal | Pertaining to an axon. (05 Mar 2000) |
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| axonal degeneration | A type of peripheral nerve fibre response to insult, wherein axon death and subsequent breakdown occurs, with secondary breakdown of the myelin sheath associated; caused by focal injury to peripheral nerve fibres; often referred to as wallerian degeneration. Synonym: axon degeneration. (05 Mar 2000) |
| axonal guidance | <cell biology> General term for mechanisms that ensure correct projections by nerve cells in developing and regenerating nervous systems. Implies accurate navigation by growth cones, the highly motile tips of growing neuronal processes. See: growth cone collapse. (12 Mar 1998) |
| axonal process | An obsolete term for axon. (05 Mar 2000) |
| axonal terminal boutons | The somewhat enlarged, often club-shaped endings by which axons make synaptic contacts with other nerve cells or with effector cells (muscle or gland cells). As isolated, by homogenizing brain or spinal cord, they contain acetylcholine and the related enzymes. Terminals contain neurotransmitters of various kinds, sometimes more than one. These can be demonstrated by chemical analysis and immunocytochemical methods. See: synapse. Synonym: axonal terminal boutons, end-feet, neuropodia, pieds terminaux, synaptic boutons, synaptic endings, synaptic terminals, terminal boutons, bouton terminaux. (05 Mar 2000) |
| axonal transport | Directed transport of organelles and molecules along a nerve cell axon. Transport can be anterograde (from the cell body) or retrograde (toward the cell body). (alberts et al., molecular biology of the cell, 3d ed, pg3) (12 Dec 1998) |
| giant axonal neuropathy | <paediatrics> A rare disorder beginning at or after the third year of life, and presenting clinically with kinky hair, progressive painless clumsiness, muscle weakness and atrophy, sensory loss, and areflexia. Pathologically, both myelinated and unmyelinated nerve fibres contain axonal spheroids packed with neurofilaments; sporadic in nature. (05 Mar 2000) |
| retrograde axonal transport | <cell biology> The transport of vesicles from the synaptic region of an axon towards the cell body: involves the interaction of MAP1C with microtubules. (11 Jan 1998) |
| acute demyelinating polyneuropathy | <neurology> A neurologic condition. Synonym: Guillain-Barre syndrome. Origin: Gr. Pathos = disease (27 Sep 1997) |
| acute inflammatory polyneuropathy | <neurology, syndrome> Acute infective polyneuritis that results in a form of peripheral neuropathy with temporary loss of movement and sensation due to inflammation of multiple nerves and loss of myelin. The exact cause is unknown but has been associated with an abnormal immune response to viral infection, particularly cytomegalovirus infection, in which there is cell-mediated immunity to a component of myelin. The disease may be autoimmune in origin and complete recovery can take up to six months. Synonym: Guillain-Barre syndrome (12 Jul 2000) |
| alcoholic polyneuropathy | <neurology> A disorder that occurs secondary to the damage to nerve cells from habitual alcohol abuse. The effects of alcoholic polyneuropathy may be due in part to the direct toxic effect alcohol has on nervous tissue in combination with specific nutritional deficiencies (for example B1 or thiamin deficiency and B12 deficiency). Common symptoms include sensory changes, numbness, tingling, muscle weakness, muscle cramps, heat intolerance, impotence, difficulty urinating, swallowing difficulty, speech impairment, diarrhoea and constipation. Origin: Gr. Pathos = disease (27 Sep 1997) |
| arsenical polyneuropathy | An axon loss polyneuropathy that results from subacute or chronic arsenic poisoning; almost always preceded by gastrointestinal symptoms; one of the heavy metal neuropathies. (05 Mar 2000) |
| axon loss polyneuropathy | A type of polyneuropathy in which axon degeneration is the sole/predominant feature; many aetiologies, particularly toxic and metabolic; on nerve conduction studies, affects amplitudes of the responses, but does not cause conduction slowing or block. Synonym: axonal polyneuropathy. (05 Mar 2000) |
| buckthorn polyneuropathy | Ascending polyneuropathy resulting from ingestion of the fruit of Karwinskia humboldtiana. (05 Mar 2000) |
| chronic inflammatory demyelinating polyneuropathy | An uncommon, acquired, demyelinating sensorimotor polyneuropathy, clinically characterised by insidious onset, and slow evolution, (either steady progression or stepwise), and chronic course; symmetrical weakness is a predominant symptom, often involving proximal leg muscles, accompanied by paresthesias, but not pain; CSF examination shows elevated protein, while electrodiagnostic studies reveal evidence of a demyelinating process, primarily conduction slowing rather than block; sometimes responds to prednisone. (05 Mar 2000) |
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