| IDA | 1) Imino-Diacetic Acid 2) Iron Deficiency Anemia &nb... |
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| DSPN | distal sensory polyneuropathy; distal symmetrical polyneuropathy |
| GnRH | Gonadotropin Releasing Hormone [HP 1898, 2034] = LHRH = Go... |
| GAN | giant axon neuropathy |
| MA | malignant arrhythmia; management and administration; mandelic acid; masseter; Master of Arts; matern... |
| Q-SART | Quantitative Sudomotor Axon Reflex Test |
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| MGA | medial giant axon |
| AIDP | Acute inflammatory demyelinating polyneuropathy |
| CIDP | Chronic Inflammatory Demyelinating Polyneuropathy |
| CIP | Critical illness polyneuropathy |
| axon loss polyneuropathy | A type of polyneuropathy in which axon degeneration is the sole/predominant feature; many aetiologies, particularly toxic and metabolic; on nerve conduction studies, affects amplitudes of the responses, but does not cause conduction slowing or block. Synonym: axonal polyneuropathy. (05 Mar 2000) |
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| axon | <cell biology> A long process of a neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells. Each nerve cell has one axon, which can be over a foot long. A nerve cell communicates with another nerve cell by transmitting signals from the branches at the end of its axon. At the terminal end of the axon, the impulses are transmitted to other nerve cells or to effector organs. In the peripheral nervous system, the larger (myelinated) axons are surrounded by a myelin sheath formed by concentric layers of plasma membrane of the schwann cell. In the central nervous system, the function of the schwann cell is supplied by oligodendrocytes (oligodendroglia). See: dendrite. (03 Jul 1999) |
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| axon degeneration | A type of peripheral nerve fibre response to insult, wherein axon death and subsequent breakdown occurs, with secondary breakdown of the myelin sheath associated; caused by focal injury to peripheral nerve fibres; often referred to as wallerian degeneration. Synonym: axon degeneration. (05 Mar 2000) |
| axon hillock | <cell biology> Tapering region between a neuron's cell body and its axon. This region is responsible for summating the graded inputs from the dendrites and producing action potentials if the threshold is exceeded. (12 Mar 1998) |
| axon reflex | An effect brought about by the passage of the nerve impulses from a sensory ending to the effector organ along divisions of the nerve fibre without traversing a synapse, e.g., as in the vasodilation resulting from stimulation of the skin or the irritation of the conjunctiva; the reaction occurs even when the nerve fibre has been sectioned and thus isolated from the nervous centres. (05 Mar 2000) |
| axon terminals | The somewhat enlarged, often club-shaped endings by which axons make synaptic contacts with other nerve cells or with effector cells (muscle or gland cells). As isolated, by homogenizing brain or spinal cord, they contain acetylcholine and the related enzymes. Terminals contain neurotransmitters of various kinds, sometimes more than one. These can be demonstrated by chemical analysis and immunocytochemical methods. See: synapse. Synonym: axonal terminal boutons, end-feet, neuropodia, pieds terminaux, synaptic boutons, synaptic endings, synaptic terminals, terminal boutons, bouton terminaux. (05 Mar 2000) |
| giant axon | <biology> Extraordinarily large unmyelinated axons found in invertebrates. Some, like the squid giant axon, can approach 1 mm diameter. Large axons have high conduction speeds, the giant axons are invariably involved in panic or escape responses and may (e.g. Crayfish) have electrical synapses to further increase speed. Vertebrate axons with high conduction velocites are much narrower: they are myelinated, allowing saltatory conduction. (17 Dec 1997) |
| cervix of the axon | The constricted portion of the axon just before the myelin sheath begins. (05 Mar 2000) |
| squid giant axon | <physiology> Large axons, up to 1mm in diameter, that innervate the mantle of the squid. Because of their large size, many of the pioneering investigations of the mechanisms underlying resting and action potentials in excitable cells were done on these fibres. (10 Mar 1998) |
| acute demyelinating polyneuropathy | <neurology> A neurologic condition. Synonym: Guillain-Barre syndrome. Origin: Gr. Pathos = disease (27 Sep 1997) |
| acute inflammatory polyneuropathy | <neurology, syndrome> Acute infective polyneuritis that results in a form of peripheral neuropathy with temporary loss of movement and sensation due to inflammation of multiple nerves and loss of myelin. The exact cause is unknown but has been associated with an abnormal immune response to viral infection, particularly cytomegalovirus infection, in which there is cell-mediated immunity to a component of myelin. The disease may be autoimmune in origin and complete recovery can take up to six months. Synonym: Guillain-Barre syndrome (12 Jul 2000) |
| alcoholic polyneuropathy | <neurology> A disorder that occurs secondary to the damage to nerve cells from habitual alcohol abuse. The effects of alcoholic polyneuropathy may be due in part to the direct toxic effect alcohol has on nervous tissue in combination with specific nutritional deficiencies (for example B1 or thiamin deficiency and B12 deficiency). Common symptoms include sensory changes, numbness, tingling, muscle weakness, muscle cramps, heat intolerance, impotence, difficulty urinating, swallowing difficulty, speech impairment, diarrhoea and constipation. Origin: Gr. Pathos = disease (27 Sep 1997) |
| arsenical polyneuropathy | An axon loss polyneuropathy that results from subacute or chronic arsenic poisoning; almost always preceded by gastrointestinal symptoms; one of the heavy metal neuropathies. (05 Mar 2000) |
| axonal polyneuropathy | A type of polyneuropathy in which axon degeneration is the sole/predominant feature; many aetiologies, particularly toxic and metabolic; on nerve conduction studies, affects amplitudes of the responses, but does not cause conduction slowing or block. Synonym: axonal polyneuropathy. (05 Mar 2000) |
| buckthorn polyneuropathy | Ascending polyneuropathy resulting from ingestion of the fruit of Karwinskia humboldtiana. (05 Mar 2000) |
| chronic inflammatory demyelinating polyneuropathy | An uncommon, acquired, demyelinating sensorimotor polyneuropathy, clinically characterised by insidious onset, and slow evolution, (either steady progression or stepwise), and chronic course; symmetrical weakness is a predominant symptom, often involving proximal leg muscles, accompanied by paresthesias, but not pain; CSF examination shows elevated protein, while electrodiagnostic studies reveal evidence of a demyelinating process, primarily conduction slowing rather than block; sometimes responds to prednisone. (05 Mar 2000) |
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