| CRD | carbohydrate-recognition domain; chronic renal disease; chronic respiratory disease; child restraint... |
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| RD | radial deviation; radiology department; rate difference; Raynaud disease; reaction of degeneration; ... |
| SCD | scleroderma; service-connected disability; sickle-cell disease; spinocerebellar degeneration; subacu... |
| GnRH | Gonadotropin Releasing Hormone [HP 1898, 2034] = LHRH = Go... |
| GAN | giant axon neuropathy |
| Q-SART | Quantitative Sudomotor Axon Reflex Test |
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| MGA | medial giant axon |
| ARMD | AGE-RELATED MACULAR DEGENERATION |
| AMD | Age related macular degeneration |
| CBD | Cortico-basal degeneration |
| axon degeneration | A type of peripheral nerve fibre response to insult, wherein axon death and subsequent breakdown occurs, with secondary breakdown of the myelin sheath associated; caused by focal injury to peripheral nerve fibres; often referred to as wallerian degeneration. Synonym: axon degeneration. (05 Mar 2000) |
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| axon | <cell biology> A long process of a neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells. Each nerve cell has one axon, which can be over a foot long. A nerve cell communicates with another nerve cell by transmitting signals from the branches at the end of its axon. At the terminal end of the axon, the impulses are transmitted to other nerve cells or to effector organs. In the peripheral nervous system, the larger (myelinated) axons are surrounded by a myelin sheath formed by concentric layers of plasma membrane of the schwann cell. In the central nervous system, the function of the schwann cell is supplied by oligodendrocytes (oligodendroglia). See: dendrite. (03 Jul 1999) |
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| axon hillock | <cell biology> Tapering region between a neuron's cell body and its axon. This region is responsible for summating the graded inputs from the dendrites and producing action potentials if the threshold is exceeded. (12 Mar 1998) |
| axon loss polyneuropathy | A type of polyneuropathy in which axon degeneration is the sole/predominant feature; many aetiologies, particularly toxic and metabolic; on nerve conduction studies, affects amplitudes of the responses, but does not cause conduction slowing or block. Synonym: axonal polyneuropathy. (05 Mar 2000) |
| axon reflex | An effect brought about by the passage of the nerve impulses from a sensory ending to the effector organ along divisions of the nerve fibre without traversing a synapse, e.g., as in the vasodilation resulting from stimulation of the skin or the irritation of the conjunctiva; the reaction occurs even when the nerve fibre has been sectioned and thus isolated from the nervous centres. (05 Mar 2000) |
| axon terminals | The somewhat enlarged, often club-shaped endings by which axons make synaptic contacts with other nerve cells or with effector cells (muscle or gland cells). As isolated, by homogenizing brain or spinal cord, they contain acetylcholine and the related enzymes. Terminals contain neurotransmitters of various kinds, sometimes more than one. These can be demonstrated by chemical analysis and immunocytochemical methods. See: synapse. Synonym: axonal terminal boutons, end-feet, neuropodia, pieds terminaux, synaptic boutons, synaptic endings, synaptic terminals, terminal boutons, bouton terminaux. (05 Mar 2000) |
| giant axon | <biology> Extraordinarily large unmyelinated axons found in invertebrates. Some, like the squid giant axon, can approach 1 mm diameter. Large axons have high conduction speeds, the giant axons are invariably involved in panic or escape responses and may (e.g. Crayfish) have electrical synapses to further increase speed. Vertebrate axons with high conduction velocites are much narrower: they are myelinated, allowing saltatory conduction. (17 Dec 1997) |
| cervix of the axon | The constricted portion of the axon just before the myelin sheath begins. (05 Mar 2000) |
| squid giant axon | <physiology> Large axons, up to 1mm in diameter, that innervate the mantle of the squid. Because of their large size, many of the pioneering investigations of the mechanisms underlying resting and action potentials in excitable cells were done on these fibres. (10 Mar 1998) |
| adipose degeneration | Abnormal formation of microscopically visible droplets of fat in the cytoplasm of cells, as a result of injury. Synonym: adipose degeneration, steatosis. (05 Mar 2000) |
| adiposogenital degeneration | A disorder characterised primarily by obesity and hypogonadotrophic hypogonadism in adolescent boys; dwarfism is rare, and when present is thought to reflect hypothyroidism. Visual loss, behavioural abnormalities, and diabetes insipidus may occur. Frohlich's syndrome often is used synonymously for this disorder, although the original case involved a pituitary tumour; most cases are thought to result from hypothalamic dysfunction in areas regulating appetite and gonadal development. The most common causes are pituitary and hypothalamic neoplasms. Synonym: adiposis orchica, adiposogenital degeneration, adiposogenital dystrophy, adiposogenital syndrome, hypophysial syndrome, hypothalamic obesity with hypogonadism. Origin: L. Fr. G. Dys-, bad, + trophe, nourishment (05 Mar 2000) |
| age-related macular degeneration | A common macular degeneration beginning with drusen of the macula and pigment disruption and sometimes leading to severe loss of central vision. (05 Mar 2000) |
| albuminous degeneration | An obsolete terms for cloudy swelling. (05 Mar 2000) |
| amyloid degeneration | Infiltration of amyloid between cells and fibres of tissues and organs. Synonym: waxy degeneration. (05 Mar 2000) |
| angiolithic degeneration | Calcareous degeneration of the walls of the blood vessels. (05 Mar 2000) |
| ascending degeneration | Retrograde degeneration of an injured nerve fibre; i.e., toward the nerve cell of the fibre, degeneration cephalad to a spinal cord lesion. (05 Mar 2000) |
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