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| Ca2+-blocker | calcium channel blocker |
|---|---|
| GnRH | Gonadotropin Releasing Hormone [HP 1898, 2034] = LHRH = Go... |
| GAN | giant axon neuropathy |
| MA | malignant arrhythmia; management and administration; mandelic acid; masseter; Master of Arts; matern... |
| QSART | quantitative sudomotor axon reflex testing |
| Q-SART | Quantitative Sudomotor Axon Reflex Test |
|---|---|
| MGA | medial giant axon |
| ARB | angiotensin receptor blocker |
| ARB | Angiotensin II receptor blocker |
| BHAT | Beta-Blocker Heart Attack Trial |
| alpha-blocker | An agent that competitively blocks alpha-adrenergic receptors; used in the treatment of hypertension. Synonym: alpha-blocker. (05 Mar 2000) |
|---|---|
| beta-blocker | <pharmacology> A large group of medications that act to block specific receptors in the nervous system. A drug that induces adrenergic blockade at either á1 or á2 adrenergic receptors or at both. The effect of beta-blockade results in slowing of the heart rate, reduction in blood pressure and reduced anxiety. Beta-blockers are used in the treatment of angina, heart arrhythmias, high blood pressure, mitral valve prolapse and other conditions. (06 Oct 1997) |
| blocker | 1. An instrument used to obstruct a passage. See: blocking agent. (05 Mar 2000) |
| calcium channel-blocker | <pharmacology> A class of drugs that act by selective inhibition of calcium ion influx through or across cell membranes or on the release and binding of calcium in intracellular pools. Calcium channel blockers are used primarily in the treatment of certain heart conditions and stroke. As they are inducers of vascular and other smooth muscle relaxation, they are also used in the treatment of hypertension and cerebrovascular spasms, as myocardial protective agents, and in the relaxation of uterine spasms. Synonym: calcium antagonist, calcium channel-blocker, slow channel-blocking agent. (12 May 2002) |
| medication, beta-blocker | Drugs that antagonise the action of adrenaline (a beta adrenergic substance) and relieve stress to the heart muscle. Beta-blockers are often used to slow the heart rate or lower the blood pressure. (12 Dec 1998) |
| H2 blocker | <pharmacology> A class of anti-ulcer medication which work through the inhibition of basal and nocturnal gastric acid secretion by competitive inhibition of the action of histamine at histamine H2 receptor sites on the parietal cells. Drugs of this type block gastric acid secretion and are therefore clinically useful in treating duodenal ulcers. Examples include cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid) and ranitidine (Zantac). (27 Sep 1997) |
| axon | <cell biology> A long process of a neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells. Each nerve cell has one axon, which can be over a foot long. A nerve cell communicates with another nerve cell by transmitting signals from the branches at the end of its axon. At the terminal end of the axon, the impulses are transmitted to other nerve cells or to effector organs. In the peripheral nervous system, the larger (myelinated) axons are surrounded by a myelin sheath formed by concentric layers of plasma membrane of the schwann cell. In the central nervous system, the function of the schwann cell is supplied by oligodendrocytes (oligodendroglia). See: dendrite. (03 Jul 1999) |
| axon degeneration | A type of peripheral nerve fibre response to insult, wherein axon death and subsequent breakdown occurs, with secondary breakdown of the myelin sheath associated; caused by focal injury to peripheral nerve fibres; often referred to as wallerian degeneration. Synonym: axon degeneration. (05 Mar 2000) |
| axon hillock | <cell biology> Tapering region between a neuron's cell body and its axon. This region is responsible for summating the graded inputs from the dendrites and producing action potentials if the threshold is exceeded. (12 Mar 1998) |
| axon loss polyneuropathy | A type of polyneuropathy in which axon degeneration is the sole/predominant feature; many aetiologies, particularly toxic and metabolic; on nerve conduction studies, affects amplitudes of the responses, but does not cause conduction slowing or block. Synonym: axonal polyneuropathy. (05 Mar 2000) |
| axon reflex | An effect brought about by the passage of the nerve impulses from a sensory ending to the effector organ along divisions of the nerve fibre without traversing a synapse, e.g., as in the vasodilation resulting from stimulation of the skin or the irritation of the conjunctiva; the reaction occurs even when the nerve fibre has been sectioned and thus isolated from the nervous centres. (05 Mar 2000) |
| axon terminals | The somewhat enlarged, often club-shaped endings by which axons make synaptic contacts with other nerve cells or with effector cells (muscle or gland cells). As isolated, by homogenizing brain or spinal cord, they contain acetylcholine and the related enzymes. Terminals contain neurotransmitters of various kinds, sometimes more than one. These can be demonstrated by chemical analysis and immunocytochemical methods. See: synapse. Synonym: axonal terminal boutons, end-feet, neuropodia, pieds terminaux, synaptic boutons, synaptic endings, synaptic terminals, terminal boutons, bouton terminaux. (05 Mar 2000) |
| giant axon | <biology> Extraordinarily large unmyelinated axons found in invertebrates. Some, like the squid giant axon, can approach 1 mm diameter. Large axons have high conduction speeds, the giant axons are invariably involved in panic or escape responses and may (e.g. Crayfish) have electrical synapses to further increase speed. Vertebrate axons with high conduction velocites are much narrower: they are myelinated, allowing saltatory conduction. (17 Dec 1997) |
| cervix of the axon | The constricted portion of the axon just before the myelin sheath begins. (05 Mar 2000) |
| squid giant axon | <physiology> Large axons, up to 1mm in diameter, that innervate the mantle of the squid. Because of their large size, many of the pioneering investigations of the mechanisms underlying resting and action potentials in excitable cells were done on these fibres. (10 Mar 1998) |
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