| B | bias |
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| bias | <statistics> In a clinical trial, bias refers to effects that a conclusion that may be incorrect as, for example, when a researcher or patient knows what treatment is being given. To avoid bias, a blinded study may be done. Any deviation of results or inferences from the truth, or processes leading to such deviation. Bias can result from several sources: one-sided or systematic variations in measurement from the true value (systematic error); flaws in study design; deviation of inferences, interpretations, or analyses based on flawed data or data collection; etc. There is no sense of prejudice or subjectivity implied in the assessment of bias under these conditions. (27 Jun 1999) |
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| publication bias | The influence of study results on the chances of publication and the tendency of investigators, reviewers, and editors to submit or accept manuscripts for publication based on the direction or strength of the study findings. Publication bias has an impact on the interpretation of clinical trials and meta-analyses. Bias can be minimised by insistence by editors on high-quality research, thorough literature reviews, acknowledgement of conflicts of interest, modification of peer review practices, etc. (12 Dec 1998) |
| selection bias | The introduction of error due to systematic differences in the characteristics between those selected and those not selected for a given study. In sampling bias, error is the result of failure to ensure that all members of the reference population have a known chance of selection in the sample. (12 Dec 1998) |
| insurance selection bias | Adverse of favourable selection bias exhibited by insurers or enrollees resulting in disproportionate enrollment of certain groups of people. (12 Dec 1998) |
| internal bias | Applied to the motile behaviour of crawling cells that, in the short term, show persistence and do not behave as true random walkers. Any intrinsic regulation of the random motile behaviour of the cell could be considered as internal bias. (18 Nov 1997) |
| ascertainment | In epidemiological and genetic research, the method by which a person, pedigree, or cluster is brought to the attention of an investigator; has a bearing on the interpretation of segregation ratios, concordance rates, linkage analysis, and other probability features. (05 Mar 2000) |
| complete ascertainment | Method by which all families with at least one affected individual in a population are certain or have an equal chance of being identified by survey or an appropriate random sampling technique. (05 Mar 2000) |
| single ascertainment | Method of ascertainment of locating affected individuals by hospital or clinic admission or another way in which probability of encountering the same family twice approaches zero; thus, the probability that a family will be ascertained is proportional to the number of affected members. (05 Mar 2000) |
| incomplete ascertainment | Method of locating affected individuals in which probability of locating any specific patient has a known value between 0 and 1. Synonym: truncate ascertainment. (05 Mar 2000) |
| total ascertainment | Method by which all members of a population at risk of a trait are discerned or equally likely to be contained in a sample thereof. (05 Mar 2000) |
| truncate ascertainment | Method of locating affected individuals in which probability of locating any specific patient has a known value between 0 and 1. Synonym: truncate ascertainment. (05 Mar 2000) |
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