| AA | Arachidonate |
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| arachidonate | <biochemistry> An essential unsaturated fatty acid that humans use to synthesise regulatory molecules such as prostaglandins and thromboxanes. It is found in fatty animal tissue such as egg yolk and liver. (09 Oct 1997) |
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| arachidonate 12-lipoxygenase | <enzyme> An enzyme that catalyses the oxidation of arachidonic acid to yield 12-hydroperoxyarachidonate (12-hpete) which is itself rapidly converted by a peroxidase to 12-hydroxy-5,8,10,14-eicosatetraenoate (12-hete). The 12-hydroperoxides are preferentially formed in platelets. Chemical name: Arachidonate:oxygen 12-oxidoreductase Registry number: EC 1.13.11.31 (12 Dec 1998) |
| arachidonate 15-lipoxygenase | <enzyme> An enzyme that catalyses the oxidation of arachidonic acid to yield 15-hydroperoxyarachidonate (15-hpete) which is rapidly converted to 15-hydroxy-5,8,11,13-eicosatetraenoate (15-hete). The 15-hydroperoxides are preferentially formed in neutrophils and lymphocytes. Chemical name: Arachidonate:oxygen 15-oxidoreductase Registry number: EC 1.13.11.33 (12 Dec 1998) |
| arachidonate 5-lipoxygenase | <enzyme> An enzyme that catalyses the oxidation of arachidonic acid to yield 5-hydroperoxyarachidonate (5-hpete) which is rapidly converted by a peroxidase to 5-hydroxy-6,8,11,14-eicosatetraenoate (5-hete). The 5-hydroperoxides are preferentially formed in leukocytes. Chemical name: Arachidonate:oxygen 5-oxidoreductase Registry number: EC 1.13.11.34 (12 Dec 1998) |
| arachidonate 8-lipoxygenase | <enzyme> From sea whip coral plexaura homomalla; catalyses the conversion of arachidonic acid to a cyclised prostanoid with a pga ring and the same side chains as the parent arachidonate Registry number: EC 1.13.11.40 Synonym: 8(r)-lipoxygenase, 8-lipoxygenase (26 Jun 1999) |
| arachidonate epoxygenase | <enzyme> Requires cytochrome p-450; uses NADPH and oxygen; forms 5,6-,8,9-11,12- and 14,15-cis-epoxyeicosatrienoic acids; p4502caa is the form isolated from rabbit renal cortex Registry number: EC 1.14.13.- Synonym: NADPH-dependent arachidonic acid epoxygenase, cytochrome p-450 epoxygenase, cytochrome p-450 arachidonate oxygenase, cyp2j2, cyp2caa, cytochrome p-450 2caa (26 Jun 1999) |
| arachidonate lipoxygenases | <enzyme> Enzymes catalyzing the oxidation of arachidonic acid to hydroperoxyarachidonates (hpetes). These products are then rapidly converted by a peroxidase to hydroxyeicosatetraenoic acids (hetes). The positional specificity of the enzyme reaction varies from tissue to tissue. The final lipoxygenase pathway leads to the leukotrienes. Registry number: EC 1.13.11.- (12 Dec 1998) |
| arachidonate monooxygenase | <enzyme> Nadph-dependent enzyme from renal cortex; not inhibited by cyclooxygenase inhibitors; forms 19-hydroxyarachidonate, 20-hydroxyarachidonate, 19-ketoarachidonate and a dicarboxylic acid Registry number: EC 1.14.13.- (26 Jun 1999) |
Synonyms : Arachidonic Acid 12-Lipoxygenase, 12 Lipoxygenase, 12-Lipoxygenase, Arachidonate, 12-Lipoxygenase, Arachidonic Acid, Arachidonate 12 Lipoxygenase, Arachidonic Acid 12 Lipoxygenase
Synonyms : Arachidonic Acid 15-Lipoxygenase, 15 Lipoxygenase, 15-Lipoxygenase, Arachidonate, 15-Lipoxygenase, Arachidonic Acid, Arachidonate 15 Lipoxygenase, Arachidonic Acid 15 Lipoxygenase
Synonyms : Arachidonic Acid 5-Lipoxygenase, LTA4 Synthase, Leukotriene A Synthase, Leukotriene A4 Synthase, Leukotriene A4 Synthetase, 5 Lipoxygenase, 5-Lipoxygenase, Arachidonate, 5-Lipoxygenase, Arachidonic Acid, Arachidonate 5 Lipoxygenase, Synthase, LTA4
Synonyms : Arachidonic Acid Lipoxygenase, Lipoxygenase, Arachidonic Acid, Lipoxygenases, Arachidonate
| arachidonate |
a salt, ester, or anion of arachidonic acid.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| arachidonate 12-lipoxygenase |
[EC 1.13.11.31] an enzyme of the oxidoreductase class that catalyzes the oxidation of arachidonate at the 12 position to form 12-hydroperoxyeicosatetraenoic acid (12-HPETE). The reaction occurs primarily in platelets and is the first step of the lipoxygenase pathway for conversion of arachidonic acid to the leukotriene 12-hydroxyeicosatetraenoic acid (12-HETE).
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| arachidonate 15-lipoxygenase |
[EC 1.13.11.33] an enzyme of the oxidoreductase class that catalyzes the oxidation of arachidonate at the 15 position to form 15-hydroperoxyeicosatetraenoic acid (15-HPETE). The reaction occurs primarily in vascular endothelium and is the first step in the conversion of arachidonic acid to 15-hydroxyeicosatetraenoic acid (15-HETE) and to lipoxins.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| arachidonate 5-lipoxygenase |
[EC 1.13.11.34] an enzyme of the oxidoreductase class that catalyzes the oxidation of arachidonate at the 5 position to form 5-hydroperoxyeicosatetraenoic acid (5-HPETE). The reaction occurs in leukocytes, particularly neutrophils, as the first step of the lipoxygenase pathway for conversion of arachidonic acid to leukotrienes.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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