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    Çׯ®·Òºó III
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AT abdominal thrusts; achievement test; Achilles tendon; Achard-Thiers [syndrome]; adaptive thermogenes...
AT III angiotensin III; antithrombin III
TAT tetanus antitoxin; thematic apperception test; thematic aptitude test; thrombin-antithrombin complex...
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AT Antithrombin
AT Antithrombin III
TAT Thrombin-antithrombin complex
TAT Thrombin antithrombin III complex
TAT Thrombin-Antithrombin III
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antithrombin Any substance that inhibits or prevents the effects of thrombin in such a manner that blood does not coagulate. A deficiency of antithrombin results in impaired inhibition of coagulation factors IIa, IXa, and Xa in plasma, causing recurrent thrombosis.
Antithrombin III, an antithrombin at present somewhat conjectural and biochemically not well characterised. Deficiency is commonly inherited as an autosomal dominant trait; one of the few known mendelizing disorders to which thrombotic disease occurs.
Normal antithrombin, an antithrombin naturally occurring in blood and certain tissues under normal conditions in contrast to abnormal states or antithrombin from other sources.
(05 Mar 2000)
antithrombin III <haematology> Antithrombin III is a protein which stimulates the removal of blood clots in the bloodstream.
Small blood clots form normally within the bloodstream, but are normally dissolved via the bodys antithrombin III.
Conditions that may have an associated low value of antithrombin III include: liver disease and DIC. Normal values are: 0.20 to 0.45 mg/ml or more than 50% of the laboratory control value.
Conditions where there is a deficiency of this important protease inhibitor can result in a condition of hypercoagulation, resulting in an increased risk for blood clot formation.
Inheritance: autosomal dominant.
(13 Jan 1998)
antithrombin test A procedure for estimating the inhibitory effect of a defibrinated specimen of plasma on the action of thrombin in converting fibrinogen to fibrin.
(05 Mar 2000)
antithrombins Plasma glycoproteins of the _ 2 globulin class that inhibit the proteolytic activity of thrombin and serve to regulate the process of blood clotting.
(18 Nov 1997)
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congenital antithrombin III deficiency Antithrombin III is a protein which stimulates the removal of blood clots in the bloodstream. Small blood clots form normally within the bloodstream, but are normally dissolved via the bodys antithrombin III. The deficiency of antithrombin III will result in an increased risk for blood clot formation causing organ damage. This is an inherited as a autosomal dominant trait.
Inheritance: autosomal dominant.
(27 Sep 1997)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 3 ÆäÀÌÁö: 1
  • Antithrombin III - »õâ A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes; it was formerly called Antithrombin II (AT II) which has now been shown to be identical to AT III; ANTITHROMBIN III DEFICIENCY, hereditary or acquired, results in thromboembolism. It is a member of the serpin superfamily. Some authors use the term antithrombin to refer to antithrombin III.
    Synonyms : AT III, Antithrombin III, Human Plasma, Antithrombin III-Alpha, Atenativ, Baxter Brand of Antithrombin, Bayer Brand of Antithrombin, Factor Xa Inhibitor, Grifols Brand of Antithrombin, Heparin Co-Factor I, Pharmacia Brand of Antithrombin, Thrombate III
  • Antithrombin III Deficiency - »õâ An absence or reduced level of Antithrombin III leading to an increased risk for thrombosis.
    Synonyms : Antithrombin 3 Deficiency, Deficiency, Antithrombin III, Antithrombin 3 Deficiencies, Antithrombin III Deficiencies, Deficiencies, Antithrombin 3, Deficiencies, Antithrombin III, Deficiency, Antithrombin 3
  • Antithrombins - »õâ An endogenous family of proteins belonging to the serpin superfamily that neutralizes the action of thrombin. Six naturally occurring antithrombins have been identified and are designated by Roman numerals I to VI. Of these, Antithrombin I (see FIBRIN) and ANTITHROMBIN III appear to be of major importance.
    Synonyms :
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antithrombin any naturally occurring or therapeutically administered substance that neutralizes the action of thrombin and thus limits or restricts blood coagulation. Six naturally occurring antithrombins have been designated by Roman numerals I to VI; antithrombins I and III are the most common and significant ones. Heparin is also considered an antithrombin.
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