| APD | action potential duration; acute polycystic disease; advanced physical diagnosis; anteroposterior di... |
|---|---|
| OHA | Oral Hypoglycemic Agents |
| CTA | Canadian Tuberculosis Association; chemotactic activity; chromotropic acid; Committee on Thrombolyti... |
| ICAAC | Interscience Conference on Antimicrobial Agents and Chemotherapy |
| NAHPA | National Association of Hospital Purchasing Agents |
| APD | antipsychotic drug |
|---|---|
| AP | antipsychotic |
| CWA | Chemical warfare agents |
| DBA | Dentin bonding agents |
| NSAID | non steroidal anti-inflammatory agents |
| antipsychotic agents | Agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in schizophrenia, senile dementia, transient psychosis following surgery or myocardial infarction, etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus. (12 Dec 1998) |
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| antipsychotic agents, butyrophenone | Those butyrophenone derivatives used in the treatment of psychoses. (12 Dec 1998) |
| antipsychotic agents, phenothiazine | Phenothiazine derivatives used in the treatment of psychoses. (12 Dec 1998) |
| antipsychotic | <pharmacology> A drug that is effective in the treatment of psychosis. Antipsychotic drugs (also called neuroleptic drugs and major tranquillisers) are a chemically diverse (including phenothiazines, thioxanthenes, butyrophenones, dibenzoxazepines, dibenzodiazepines and diphenylbutylpiperidines) but pharmacologically similar class of drugs used to treat schizophrenic, paranoid, schizoaffective and other psychotic disorders, acute delirium and dementia and manic episodes (during induction of lithium therapy), to control the movement disorders associated with Huntington disease, Gilles de la Tourette's syndrome and ballismus and to treat intractable hiccups and severe nausea and vomiting. Antipsychotic agents bind to dopamine, histamine, muscarinic cholinergic, a adrenergic and serotonin receptors. Blockade of dopaminergic transmission in various areas is thought to be responsible for their major effects: antipsychotic action by blockade in the mesolimbic and mesocortical areas, extrapyramidal side effects (dystonia, akathisia, parkinsonism and tardive dyskinesia) by blockade in the basal ganglia and antiemetic effects by blockade in the chemoreceptor trigger zone of the medulla. Sedation and autonomic side effects (orthostatic hypotension, blurred vision, dry mouth, nasal congestion and constipation) are caused by blockade of histamine, cholinergic and adrenergic receptors. (13 Nov 1997) |
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| antipsychotic agent | A functional category of neuroleptic drugs that are helpful in the treatment of psychosis and have a capacity to ameliorate thought disorders (e.g., chlorpromazine, haloperidol). See: neuroleptic. Synonym: antipsychotic, major tranquilliser. (05 Mar 2000) |
| abortifacient agents | Chemical substances that interrupt pregnancy after implantation. (12 Dec 1998) |
| abortifacient agents, non-steroidal | Non-steroidal chemical compounds with abortifacient activity. (12 Dec 1998) |
| abortifacient agents, steroidal | Steroidal compounds with abortifacient activity. (12 Dec 1998) |
| adrenergic agents | Drugs that act on adrenergic receptors or affect the life cycle of adrenergic transmitters. Included here are adrenergic agonists and antagonists and agents that affect the synthesis, storage, uptake, metabolism, or release of adrenergic transmitters. (12 Dec 1998) |
| alkylating agents | Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agent, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases. (12 Dec 1998) |
| anti-allergic agents | Agents that are used to treat allergic reactions. most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (12 Dec 1998) |
| anti-allergic and respiratory system agents | A collective term for drugs used to treat allergic reactions as well as those drugs that produce an effect on the respiratory system. (12 Dec 1998) |
| anti-anxiety agents | Agents that alleviate anxiety, tension, and neurotic symptoms, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. Some are also effective as anticonvulsants, muscle relaxants, or anaesthesia adjuvants. Adrenergic beta-antagonists are commonly used in the symptomatic treatment of anxiety but are not included here. Substances with a benzodiazepine ring structure widely used to treat anxiety and neuroses. Drugs in this class also generally have sedative or weak hypnotic properties and may be effective as muscle relaxants, anticonvulsants, and anaesthesia adjuvants. (12 Dec 1998) |
| anti-arrhythmia agents | Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (12 Dec 1998) |
| anti-asthmatic agents | Drugs that are used to treat asthma. (12 Dec 1998) |
| anticarcinogenic agents | Agents that reduce the frequency or rate of spontaneous or induced tumours independently of the mechanism involved. They differ from antineoplastic agent in that they prevent neoplasms from forming. The anticarcinogenic substances can be divided into three categories. The first consists of compounds that prevent the formation of carcinogens from precursor substances. The second group consists of "blocking agents" which inhibit carcinogenesis by preventing carcinogenic agents from reaching or reacting with critical target sites in the tissues. The third group is the "suppressor agents" which act by suppression of expression of neoplasia in cells previously exposed to carcinogens that would otherwise cause neoplasms. (12 Dec 1998) |
| anticestodal agents | Agents used to treat tapeworm infestations in man or animals. (12 Dec 1998) |
| anticholesteraemic agents | Substances that promote a reduction of blood cholesterol levels. (12 Dec 1998) |
Synonyms : Antipsychotic Drugs, Antipsychotics, Major Tranquilizers, Neuroleptic Agents, Neuroleptic Drugs, Tranquillizing Agents, Major, Agents, Antipsychotic, Agents, Major Tranquilizing, Agents, Major Tranquillizing, Agents, Neuroleptic, Drugs, Antipsychotic
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