| C-ANCA | cytoplasmic anti-neutrophilic cytoplasmic antibody |
|---|---|
| ANCA | antineutrophil cytoplasm antibody |
| AGA | accelerated growth area; allergic granulomatosis and angiitis; American Gastroenterological Associat... |
| AHMA | American Holistic Medicine Association; antiheart muscle autoantibody |
| IAA | imidazoleacetic acid; indoleacetic acid; infectious agent, arthritis; insulin autoantibody; Internat... |
| ANCA | Anti-neutrophil cytoplasmic autoantibody |
|---|---|
| ANCAs | Antineutrophil cytoplasmic autoantibodies |
| MPO-ANCA | Myeloperoxidase antineutrophil cytoplasmic antibody |
| IAA | Insulin autoantibody |
| ANCA | Anti-Neutrophil Cytoplasmic Antibodies |
| antibodies, antineutrophil cytoplasmic | Autoantibodies directed against cytoplasmic constituents of polymorphonuclear leukocytes and/or monocytes. They are used as specific markers for wegener's granulomatosis and other diseases, though their pathophysiological role is not clear. Anca are routinely detected by indirect immunofluorescence with three different patterns: c-anca (cytoplasmic), p-anca (perinuclear), and atypical anca. (12 Dec 1998) |
|---|---|
| anti-idiotype autoantibody | <immunology> An autoantibody, the specificity of which is directed against one of one's own idiotypes. See: anti-idiotype antibody. Synonym: idiotype autoantibody. (05 Mar 2000) |
| autoantibody | Antibody that reacts with an antigen that is a normal component of the body. Obviously this can lead to some problems and autoimmunity has been proposed as a causative factor in a number of diseases such as rheumatoid arthritis. See: systemic lupus erythematosus, Hashimoto's thyroiditis, myasthenia gravis. (18 Nov 1997) |
| warm autoantibody | An autoantibody that reacts optimally at 37°C. (05 Mar 2000) |
| cold autoantibody | An autoantibody that reacts at temperatures below 37°c. (05 Mar 2000) |
| haemagglutinating cold autoantibody | A cold autoagglutinin. (05 Mar 2000) |
| Donath-Landsteiner cold autoantibody | An autoantibody of the IgG class responsible for paroxysmal cold haemoglobinuria; it is adsorbed to red cells only at temperatures of 20°C or lower, causing the red cells to lyse in the presence of complement at higher temperatures; it has only slight agglutinating properties in spite of its marked lytic activity, and has a specificity within the blood group P; it is also occasionally present for short periods of time following measles and other infections, and formerly was frequently associated with syphilis. Synonym: cold haemolysin. (05 Mar 2000) |
| idiotype autoantibody | <immunology> An autoantibody, the specificity of which is directed against one of one's own idiotypes. See: anti-idiotype antibody. Synonym: idiotype autoantibody. (05 Mar 2000) |
| receptors, cytoplasmic and nuclear | Proteins in the cytoplasm or nucleus that specifically bind signalling molecules and trigger changes which influence the behaviour of cells. The major groups are the steroid hormone receptors, which usually are found in the cytoplasm, and the thyroid hormone receptors, which usually are found in the nucleus. Receptors, unlike enzymes, generally do not catalyze chemical changes in their ligands. (12 Dec 1998) |
| cistern of cytoplasmic reticulum | See: cisterna. (05 Mar 2000) |
| cytoplasmic | Relating to the cytoplasm. (05 Mar 2000) |
| cytoplasmic antiproteinase | <chemical> An intracellular serine proteinase inhibitor; 376 amino acids, mw 38-43 kD; amino acid sequence given in first source Pharmacological action: serine proteinase inhibitors Synonym: human cap (26 Jun 1999) |
| cytoplasmic bridge | <plant biology> Thin strand of cytoplasm linking cells as in higher plants, Volvox, between nurse cells and developing eggs and between developing sperm cells. Unlike gap junctions, allows the transfer of large macromolecules. (18 Nov 1997) |
| cytoplasmic bridges | Slender cytoplasmic strands connecting adjacent cells; in histological sections of the epidermis and other stratified squamous epithelia, the bridge's are processes attached by a desmosome and are shrinkage artifacts of fixation; true bridge's with cytoplasmic confluence exist between incompletely divided germ cells. Synonym: cell bridges, cytoplasmic bridges. (05 Mar 2000) |
| cytoplasmic gene | <molecular biology> A gene which occurs outside the nucleus of an eukaryote or outside the regular chromosomes of a bacteria. (09 Oct 1997) |
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