| AFP | Alpha(α) Feto-Protein [HP 1826, 1858, 1859, 2265] ; Oncofetal Antigens &nbs... |
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| Anti-ENA | Anti-Extractable Nuclear Antigens |
| CEA | Carcino-Embryonic Antigen [HP 1825-6] ; Oncofetal Antigens ; Glycopro... |
| CREG | Cross REactive Group (of HLA Antigens) |
| ANA | acetylneuraminic acid; American Narcolepsy Association; American Neurological Association; American ... |
| APV | Avian polyomavirus |
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| HaPV | Hamster polyomavirus |
| HLA | Histocompatibility Antigens |
| Ipa | Invasion plasmid antigens |
| MHC | Major histocompatibility antigens |
| antigens, polyomavirus transforming | Polyomavirus antigens which cause infection and cellular transformation. The large t antigen is necessary for the initiation of viral DNA synthesis, repression of transcription of the early region and is responsible in conjunction with the middle t antigen for the transformation of primary cells. Small t antigen is necessary for the completion of the productive infection cycle. (12 Dec 1998) |
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| polyomavirus | <virology> A papovavirus (genus Polyomavirus, family Papovaviridae) which is a DNA tumour virus with very small genome. Polyoma was isolated from mice, in which it causes no obvious disease, but when injected at high titre into baby rodents, including mice, it causes tumours of a wide variety of histological types (hence polyoma). In vitro, infected mouse cells are permissive for virus replication and thus are killed, whilst hamster cells undergo abortive infection and at a low frequency become transformed. It is capable of producing parotid tumours in mice and sarcomas in hamsters as well as tumours in other laboratory animals. Synonym: mouse parotid tumour virus. (22 Sep 2002) |
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| polyomavirus hominis 1 | <virology> A species of polyomavirus apparently infecting over 90% of children but not clearly associated with any clinical illness in childhood. The virus remains latent in the body throughout life and can be reactivated under certain circumstances. (12 Dec 1998) |
| polyomavirus hominis 2 | <virology> A species of polyomavirus, originally isolated from the brain of a patient with progressive multifocal leukoencephalopathy. The patient's initials j.c. Gave the virus its name. Infection is not accompanied by any apparent illness but serious demyelinating disease can appear later, probably following reactivation of latent virus. (12 Dec 1998) |
| polyomavirus macacae | <virology> A species of polyomavirus isolated from rhesus monkey kidney tissue, which produces malignancy in human and newborn hamster kidney cell cultures and tumours on inoculation into newborn hamsters. (12 Dec 1998) |
| receptors, transforming growth factor beta | Cell-surface proteins that bind transforming growth factor beta and trigger changes influencing the behaviour of cells. Two types of transforming growth factor receptors have been recognised. They differ in affinity for different members of the transforming growth factor beta family and in cellular mechanisms of action. Transforming growth factor alpha binds to the same receptors as epidermal growth factor (see receptors, epidermal growth factor-urogastrone). (12 Dec 1998) |
| pro-transforming growth factor-alpha processing protease | <enzyme> Converts membrane-bound protgf-alpha to soluble tgf-alpha; mw 84 kD Registry number: EC 3.4.21.- Synonym: protgf-alpha converting enzyme, protgfalpha processing protease (26 Jun 1999) |
| transforming agent | A substance which is able to induce mitosis of certain eukaryotic cells. (09 Oct 1997) |
| transforming factor | The DNA responsible for bacterial transformation. (05 Mar 2000) |
| transforming gene | <molecular biology> Genes, originally of tumour viruses, responsible for their ability to transform cells. The term now serves as an operational definition of oncogenes. (18 Nov 1997) |
| transforming growth factor | <growth factor> Proteins secreted by transformed cells that can stimulate growth of normal cells. Unfortunate misnomer, since they induce aspects of transformed phenotype, such as growth in semi solid agar, but do not actually transform. Transforming growth factor alpha, 50 amino acid polypeptide originally isolated from viral transformed rodent cells, contains EGF like domain and binds to EGF receptor. Stimulates growth of microvascular endothelial cells, i.e. Is angiogenic. Transforming growth factor beta a homodimer of two 112 chains, polypeptide is secreted by many different cell types, stimulates wound healing but in vitro is also a growth inhibitor for certain cell types. The transforming growth factor family includes many of the bone morphogenetic proteins. Acronym: TGF (18 Nov 1997) |
| transforming growth factor alpha | Factor isolated in a variety of tissues including epithelium, and maternal decidua. It is closely related to epidermal growth factor (epidermal growth factor-urogasterone) and binds to the egf receptor. Tgf-alpha acts synergistically with tgf-beta in inducing phenotypic transformation, but its physiological role is unknown. (12 Dec 1998) |
| transforming growth factor beta | Factor synthesised in a wide variety of tissues including platelets, placenta, and both normal and transformed cell lines. It acts synergistically with tgf-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. Tgf-beta also has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. There are at least three forms of tgf-beta: tgf-beta1, tgf-beta2, and tgf-beta1.2. The latter is a heterodimer made up of both tgf-beta1 and tgf-beta2. (12 Dec 1998) |
| transforming growth factors | <chemical> Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumour-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, transforming growth factor alpha and transforming growth factor beta. Chemical name: Animal growth regulators, transforming growth factors (12 Dec 1998) |
| transforming oncogene | <molecular biology> A gene that upon transfection converts a previously immortalised cell to the malignant phenotype. (09 Oct 1997) |
| transforming virus | <molecular biology, virology> Viruses capable of inducing malignant transformation of animal cells in culture. Among the Oncovirinae, nondefective viruses that lack oncogenes can induce tumours such as leukaemias in animals, but cannot transform in vitro. On acquisition of oncogenes they become (acute) transforming viruses. (18 Nov 1997) |
Synonyms : Polyomaviruses Large T Proteins, Polyomaviruses Middle T Proteins, Polyomaviruses Small T Proteins, Antigens, Polyomavirus Tumor, Antigens, SV40 T, Proteins, Polyomavirus T, Proteins, SV40 T, T Antigens, SV40, T Proteins, Polyomavirus, T Proteins, SV40
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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