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  • CD4
    CD4
  • T antigens
    TÇ׿ø
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  • HLA= human leukocyte antigen ; hist ocompatibility antigens ; tran splan tation antigens
    HLA<Á¶Á÷ÀûÇÕÀ̽Ä>Ç׿ø, ÀιéÇ÷±¸Ç׿ø.
  • CD4+ cell
    CD4+ ¼¼Æ÷
  • HLA= human leukocyte antigen ; histocompatibility antigens ; transplantation anti
    HLA<Á¶Á÷ÀûÇÕÀ̽Ä>Ç׿ø, »ç¶÷¹éÇ÷±¸Ç׿ø.
  • Yka antigens
    YKa Ç׿ø
  • granulocyte-erythrocyte antigens
    °ú¸³±¸ÀûÇ÷±¸Ç׿ø
  • granulocyte-monocyte antigens
    °ú¸³±¸´Ü±¸Ç׿ø
  • granulocyte-monocyte-lymphocyte antigens
    °ú¸³±¸´Ü±¸¸²ÇÁ±¸Ç׿ø
  • granulocyte-platelet-lymphocyte antigens
    °ú¸³±¸Ç÷¼ÒÆÇ¸²ÇÁ±¸Ç׿ø
  • granulocyte-specific antigens
    °ú¸³±¸Æ¯ÀÌÇ׿ø
  • histocompatibility antigens
    Á¶Á÷ÀûÇÕ Ç׿ø
  • platelet-specific antigens
    Ç÷¼ÒÆÇƯÀÌÇ׿ø
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  • granulocyte-erythrocyte antigens
    °ú¸³±¸ÀûÇ÷±¸Ç׿ø
  • granulocyte-monocyte antigens
    °ú¸³±¸´Ü±¸Ç׿ø
  • granulocyte-monocyte-lymphocyte antigens
    °ú¸³±¸´Ü±¸¸²ÇÁ±¸Ç׿ø
  • granulocyte-platelet-lymphocyte antigens
    °ú¸³±¸Ç÷¼ÒÆÇ¸²ÇÁ±¸Ç׿ø
  • granulocyte-specific antigens
    °ú¸³±¸Æ¯ÀÌÇ׿ø
  • histocompatibility antigens
    Á¶Á÷ÀûÇÕ Ç׿ø
  • human platelet antigens=HPA
    ÀÎÇ÷¼ÒÆÇÇ׿ø
  • platelet-specific antigens
    Ç÷¼ÒÆÇƯÀÌÇ׿ø
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  • carcinoembryonic antigens
    ¾Ï¹è¾ÆÇ׿ø(äßÛÏä´ù÷ê«)
  • class II MHC antigens
    "Á¦ 11 ·ù(×¾) MHC Ç׿ø(ù÷ê«), (ÔÒ) 1-region-associated antigens"
  • Epa antigens
    EPa Ç׿ø(ù÷ê«)
  • H-2 antigens
    H-2 Ç׿ø(ù÷ê«)
  • HLA antigens
    HLA Ç׿ø (ù÷ê«)
KMLE ÀÇÇоà¾î »çÀü À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 1
ICL Idiopathic CD4 + T Lymphocytopenia
CD4 HIV helper cell count
ICL idiopathic CD4 T-cell lymphocytopenia; iris-clip lens; isocitrate lyase
AFP Alpha(¥á) Feto-Protein [HP 1826, 1858, 1859, 2265]
  ; Oncofetal Antigens
 &nbs...
Anti-ENA Anti-Extractable Nuclear Antigens
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CD4+ CD4 positive
h-CD4 human CD4
HLA Histocompatibility Antigens
ICL Idiopathic CD4 T lymphocytopenia
Ipa Invasion plasmid antigens
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antigens, CD4 <immunology> 55-kD glycoproteins originally defined as differentiation antigens on T-lymphocytes, but also found on other cells including monocytes/macrophages. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MHC (major histocompatibility complex) class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. Cd4 antigens also serve as HIV receptors, binding directly to the envelope protein gp120 on HIV.
The protein structure on the surface of a human cell that allows HIV to attach, enter, and thus infect a cell. CD4 receptors are present on CD4 cells (helper T-cells), macrophages and dendritic cells, among others. Normally, CD4 acts as an accessory molecule, forming part of larger structures (such as the T-cell receptor) through which Tcells and other cells signal each other.
(12 Dec 1998)
antigens, CD40 <immunology> Differentiation antigens found on all mature B-lymphocytes and some epithelial cells, carcinomas, and lymphoid dendritic cells. This is a member of the tumour necrosis factor superfamily. Evidence suggests that CD40-dependent activation of B-cells is important for generation of memory B-cells within the germinal centres.
(12 Dec 1998)
antigens, CD44 <immunology> Acidic sulfated integral membrane glycoproteins expressed in several alternatively spliced and variable glycosylated forms on a wide variety of cell types including mature T-cells, B-cells, medullary thymocytes, granulocytes, macrophages, erythrocytes, and fibroblasts. Cd44 antigens are the principle cell surface receptors for hyaluronate and this interaction mediates binding of lymphocytes to high endothelial venules.
(12 Dec 1998)
antigens, CD45 <immunology> High-molecular weight glycoproteins uniquely expressed on the surface of all leukocytes and their haemopoietic progenitors. The CD45 family consists of multiple members that are all products of a single gene. Cd45 expression is necessary for signalling through the T-cell receptor.
(12 Dec 1998)
CancerWEB ¿µ¿µ ÀÇÇлçÀü À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
absolute CD4 count The number of helper T-lymphocytes in a cubic millimeter of blood. With HIV, the absolute CD4 count declines as the infection progresses. The absolute CD4 count is frequently used to monitor the extent of immune suppression in persons with HIV. Also called a T4 count.
(12 Dec 1998)
CD4 <immunology> 55-kD glycoproteins originally defined as differentiation antigens on T-lymphocytes, but also found on other cells including monocytes/macrophages. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MHC (major histocompatibility complex) class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. Cd4 antigens also serve as HIV receptors, binding directly to the envelope protein gp120 on HIV.
The protein structure on the surface of a human cell that allows HIV to attach, enter, and thus infect a cell. CD4 receptors are present on CD4 cells (helper T-cells), macrophages and dendritic cells, among others. Normally, CD4 acts as an accessory molecule, forming part of larger structures (such as the T-cell receptor) through which Tcells and other cells signal each other.
(12 Dec 1998)
CD4/CD8 count The ratio of the number of helper-inducer T lymphocytes to cytotoxic-suppressor T lymphocytes, as measured by monoclonal antibodies to the CD4 surface antigen found on helper-inducer T-cells, and the CD8 surface antigen found on cytotoxic-suppressor T-cells. In healthy individuals, the H/S ratio ranges between 1.6 and 2.2.When the body mounts an immune response, as against a virus or a transplant, the ratio is almost always reduced because of a decrease in the number of circulating helper-inducer cells and an increase in suppressor cells. The CD4/CD8 count has been used to monitor for signs of organ rejection after transplants, and more recently has become a tool for assessing the relative condition of HIV patients. With the CD4 absolute count and the CD4 lymphocyte percentage, it provides a way of gauging the progression from HIV to AIDS.
(05 Mar 2000)
CD4:CD8 ratio The ratio of CD4 to CD8 cells. A common measure of immune system status that is around two in healthy individuals. The ratio of T-lymphocytes that express the CD4 antigen to those that express the CD8 antigen. This value is commonly assessed in the diagnosis and staging of diseases affecting the immune system including HIV infection.
(12 Dec 1998)
CD4 cell T helper cells which are targets for HIV infection.
(09 Oct 1997)
CD4 cell count The most commonly used surrogate marker for assessing the state of the immune system. As CD4 cell count declines, the risk of developing opportunistic infections increases. The normal range for CD4 cell counts is 500 to 1500 per cubic millimetre of blood. CD4 count should be rechecked at least every six to twelve months if CD4s are greater than 500/mm3. If the count is lower, testing every three months is advised.
(09 Oct 1997)
CD4 count, absolute The number of helper T-lymphocytes in a cubic millimeter of blood. With HIV, the absolute CD4 count declines as the infection progresses. The absolute CD4 count is frequently used to monitor the extent of immune suppression in persons with HIV. Also called a T4 count.
(12 Dec 1998)
CD4 immunoadhesins <immunology> Chimeric molecules resulting from the fusion of recombinant soluble CD4 to the fc portion of immunoglobulins. These have potential use in the therapy of aids since they possess both the gp120-binding and HIV-blocking properties of rCD4 as well as the long plasma half-life and fc receptor-binding functions of immunoglobulin.
(12 Dec 1998)
CD4 lymphocyte A specific type of lymphocyte, derived from the thymus gland, that plays an important role in cellular immunity. T4 lymphocytes (CD4 cells) are decreased (absolute counts less than 200) in patients with AIDS resulting in compromised immune function.
(27 Sep 1997)
CD4 lymphocyte count A count of the number of CD4-positive lymphocytes in the blood. Determination requires the use of a fluorescence-activated flow cytometer.
(12 Dec 1998)
CD4-positive T-lymphocytes A critical subpopulation of regulatory T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the t4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes, which includes both the helper-inducer (T-lymphocytes, helper-inducer) and suppressor-inducer (T-lymphocytes, suppressor-inducer) T-cells.
(12 Dec 1998)
t-lymphocytopenia, idiopathic CD4-positive Reproducible depletion of CD4+ lymphocytes below 300 per cubic millimeter in the absence of HIV infection or other known causes of immunodeficiency. This is a rare, heterogeneous syndrome and does not appear to be caused by a transmissible agent.
(12 Dec 1998)
ABO antigens <haematology, immunology> A system of genetically determined antigens (proteins) located on the surface of the erythrocyte.
The presence of these specific antigens gives a blood its unique properties. Because of the antigen differences existing between individuals, blood groups are significant in blood transfusions, maternal-foetal incompatibilities (erythroblastosis foetalis), tissue and organ transplantation.
(27 Sep 1997)
Am antigens Allotypic determinants (antigens) on human immunoglobulin alpha heavy chains.
(05 Mar 2000)
antigens Substances which are capable, under appropriate conditions, of inducing a specific immune response and of reacting with the products of that response, that is, with specific antibodies or specifically sensitised T-lymphocytes, or both. Antigens may be soluble substances, such as toxins and foreign proteins, or particulates, such as bacteria and tissue cells; however, only the portion of the protein or polysaccharide molecule known as the antigenic determinant (epitopes) combines with antibody or a specific receptor on a lymphocyte.
(12 Dec 1998)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 1
  • Antigens, CD4 - »õâ 55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. CD4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN GP120.
    Synonyms : CD4 Antigen, Receptors, Surface CD4, Surface CD4 Receptor, Antigen, CD4, Antigens, T-Cell T4, CD4 Receptor, Surface, CD4 Receptors, Surface, Surface CD4 Receptors, T-Cell T4 Antigens, T4 Antigens, T Cell
  • Antigens, CD40 - »õâ A member of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. It is found on mature B-LYMPHOCYTES and some EPITHELIAL CELLS, lymphoid DENDRITIC CELLS. Evidence suggests that CD40-dependent activation of B-cells is important for generation of memory B-cells within the germinal centers. Mutations of the gene for CD40 antigen result in HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 3. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
    Synonyms : CD40 Antigen, CDw40 Antigen, TNFRSF5 Receptor, Antigen, CD40, Antigen, CDw40, Receptor, TNFRSF5
  • Antigens, CD43 - »õâ A sialic acid-rich protein and an integral cell membrane mucin. It plays an important role in activation of T-LYMPHOCYTES.
    Synonyms : CD43 Antigen, Leukocyte Sialoglycoprotein, Leukosialin, Sialophorin, Antigen, CD43, Sialoglycoprotein, Leukocyte
  • Antigens, CD44 - »õâ Acidic sulfated integral membrane glycoproteins expressed in several alternatively spliced and variable glycosylated forms on a wide variety of cell types including mature T-cells, B-cells, medullary thymocytes, granulocytes, macrophages, erythrocytes, and fibroblasts. CD44 antigens are the principle cell surface receptors for hyaluronate and this interaction mediates binding of lymphocytes to high endothelial venules. (From Abbas et al., Cellular and Molecular Immunology, 2d ed, p156)
    Synonyms : CD44 Antigen, Hyaluronan Receptor, Hyaluronic Acid Binding Protein, Antigen, CD44, Hyaluronan Binding Protein, Receptor, Hyaluronan
  • Antigens, CD45 - »õâ High-molecular weight glycoproteins uniquely expressed on the surface of all leukocytes and their hemopoietic progenitors. The CD45 family consists of multiple members that are all products of a single gene. CD45 expression is necessary for signaling through the T-cell receptor.
    Synonyms : 2H4 Antigens, B220 Antigen, CD45 Antigen, CD45R0 Antigens, CD45RB Antigens, CD45RCAntigens, L-CA Antigens, Leukocyte Common Antigen, RT7 Antigen, T200 Antigens, UCHL1 Antigens, Antigen, B220, Antigen, CD45, Antigen, Leukocyte Common, Antigen, RT7, Antigens, 2H4
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