| MAD | Major Antigenic Determinant |
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| AD | accident dispensary; acetate dialysis; active disease; acute dermatomyositis; addict, addiction; ade... |
| NAD | neutrophil actin dysfunction; new antigenic determinant; nicotinamide adenine dinucleotide; nicotini... |
| MAP | Multiple Antigenic Peptide |
|---|---|
| VAT | variant antigenic type |
| antigenic drift | <immunology> A change that occurs on the molecular level to effect a change in the antigenicity of a bacteria or virus. Antigenic drift occurs naturally and more rapidly in certain viruses (for example HIV). It is antigenic drift which complicates the development of an effective HIV (AIDS) vaccine. (27 Sep 1997) |
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| antigenic | Having the properties of an antigen (allergen). Synonym: allergenic, immunogenic. (05 Mar 2000) |
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| antigenic competition | Competition that occurs when two different antigens, each of which can evoke an immunological response when inoculated alone, are mixed in equal quantities and inoculated together; the response may be to only one, that to the other being largely or entirely suppressed. (05 Mar 2000) |
| antigenic complex | A composite of different antigenic structures, such as a cell or a bacterium, or, by extension, a molecule containing two or more determinant groups of different antigenic specificities. (05 Mar 2000) |
| antigenic determinant | That part of an antigenic molecule against which a particular immune response is directed. For instance a tetra to penta peptide sequence in a protein, a tri to penta glycoside sequence in a polysaccharide. In the animal most antigens will present several or even many antigenic determinants simultaneously. See: hapten. (18 Nov 1997) |
| antigenic modulation | Loss of detectable antigen from the surface of a cell after incubation with antibodies. This is one method in which some tumours escape detection by the immune system. Antigenic modulation of target antigens also reduces the therapeutic effectiveness of treatment by monoclonal antibodies. (12 Dec 1998) |
| antigenic shift | Mutation, i.e., sudden change in molecular structure of RNA/DNA in microorganisms, especially viruses, which produces new strains of the microorganism; hosts previously exposed to other strains have little or no acquired immunity to the new strain; antigenic shift is believed to be the explanation for the occurrence of strains of microorganisms, such as the influenza virus, associated with large scale epidemics. (05 Mar 2000) |
| antigenic switching | <immunology> The process by which a pathogenic microbe's genetic structure is altered tochange its surface antigens inorder to avoid being detected by the host's immune system. (09 Oct 1997) |
| antigenic variation | The phenomenon of changes in surface antigens in parasitic populations of Trypanosoma and Plasmodium (and some other parasitic protozoa) in order to escape immunological defense mechanisms. at least 100 different surface proteins have been found to appear and disappear during antigenic variation in a clone of trypanosomes. Each antigen is encoded in a separate gene. Antigenic variation is also known to occur in free living Protozoa and certain bacteria. (18 Nov 1997) |
| idiotypic antigenic determinant | The antigenic specificites defined by the unique sequences (idiotopes) of the antigen combining site. Thus anti-idiotype antibodies combine with those specific sequences, may block immunological reactions and may resemble the epitope to which the first antibody reacts. (18 Nov 1997) |
| genetic drift | <genetics> The random change of the occurance of a particular gene in a population, genetic drift is thought to be one cause of speciation when a group oforganisms is separated from its parent population. (09 Oct 1997) |
| pure random drift | That which has random components only with an average value of zero and no systematic effects. Brownian movement in a still container shows pure random drift but in the Mississippi shows a steady downstream tendency. (05 Mar 2000) |
| drift | Collectively, stream invertebrates (almost wholly the aquatic larval stages of insects) that voluntarily or accidentally leave the substrate to move or float with the current, as well as terrestrial invertebrates that drop into the stream. Also, any detrital material transported in the water current. (09 Oct 1997) |
| drift cyclotron loss cone instabilities | (DCLC) This is an electrostatic microinstability (frequencies at harmonics of the ion cyclotron frequency) which is of major concern in small mirror devices. Mode is driven by radial gradients in the electron density, and causes loss of ions due to non-conservation of magnetic moment (see adiabatic invariant) as they interact with the mode, and are dispersed in velocity space into the loss cone. Stabilisation is accomplished by increasing the plasma size and by partially filling the loss cone with a continuous extermal warm plasma stream. (09 Oct 1997) |
| drift feeder | Fish and other predators that forage on invertebrates drifting on the water surface or in the water column. (09 Oct 1997) |
| drift line | An accumulation of water-carried debris along a contour or at the base of vegetation that provides direct evidence of prior inundation and often indicates the directional flow of flood waters. (09 Oct 1997) |
| antigenic drift |
Antigenic drift refers to mutations in the influenza virus that cause changes in the virus's surface proteins over time. Those proteins (hemagglutinin and neuraminidase) are the causes of the body's immune reaction (i.e., they are antigens). Mutations occur almost yearly in the influenza virus, and while the change might not be a major one (which would then be called an antigenic shift), they are sufficient to lessen your body's ability to protect you with antibodies. ...
출처: en.wikipedia.org/wiki/Antigenic_drift
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| antigenic drift |
Many viruses mutate frequently in order to avoid destruction by the immune systems of their hosts. The gradual evolution of viral strains that results from these mutations is known as antigenic drift.
출처: www.epidemic.org/glossaryText/glossaryA-B.html
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