| ¿µ¹® | IDDM(Insulin-Dependent Diabetes Mellitus) | ÇÑ±Û | Àν¶¸°ÀÇÁ¸´ç´¢º´ |
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| ¼³¸í | IDDMÀº ´ç´¢º´ÀÇ Ä¡·á¿¡ ¹Ýµå½Ã Àν¶¸°ÀÌ ÇÊ¿äÇÑ °æ¿ì¸¦ ¸»ÇÑ´Ù. ÁÖ·Î ¿øÀÎÀÌ ÀÌÀÚ¿¡ ÀÖ´Â Àν¶¸°À» ºÐºñÇÏ´Â ¼¼Æ÷ÀÇ ÆÄ±«À̸ç ÀÌ·Î ÀÎÇØ¼ ´ç´¢º´ÀÇ Ä¡·áÁ¦·Î ¾²ÀÌ´Â Àν¶¸°ÀÇ ºÐºñ¸¦ ÃËÁøÇÏ´Â ¾à¹°ÀÌ ÀÌ IDDM¿¡¼´Â ¾²ÀÏ ¼ö°¡ ¾ø°í ¿ÀÁ÷ Àν¶¸°¸¸ÀÌ Ä¡·áÁ¦·Î ¾µ ¼ö°¡ ÀÖ´Ù. ÀüÇüÀûÀÎ Àν¶¸° ÀÇÁ¸Çü ´ç´¢º´Àº ¼Ò¾Æ¿¡¼ ÈçÈ÷ ¹ß»ýÇϰí Àν¶¸° ºÐºñ¼¼Æ÷ÀÇ ÆÄ±«¿¡ ÀÇÇØ¼ Àν¶¸° ºÐºñ´ÉÀº °ÅÀÇ ¾ø´Ù. |
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| ¿µ¹® | antiglobulin antibody | ÇÑ±Û | Çױ۷κҸ°Ç×ü |
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| ¼³¸í | Ç×ü¿¡ ´ëÇÑ Ç×ü, Áï Æ¯Á¤ Ç×ü¿Í °áÇÕÇÒ ¼ö ÀÖ´Â Ç×ü. ´ë°³ Àΰ£ÀÇ Ç×ü¸¦ Áã¿¡ ÁÖ»çÇÏ¿© Áã·Î ÇÏ¿©±Ý Àΰ£ Ç×ü¿¡ ´ëÇÑ Ç×ü¸¦ ¸¸µé°Ô ÇÑ´Ù(Áã¿¡ À־ Àΰ£ÀÇ Ç×üµµ ¿ÜºÎ¿¡¼ µé¾î¿Â ¹°ÁúÀ̹ǷÎ). À̰ÍÀº ¿©·¯ °¡Áö ½ÇÇè¿¡¼ Àΰ£ÀÇ Æ¯Á¤Ç×ü¸¦ °ËÃâÇϴµ¥ ÀÌ¿ëÇÑ´Ù. |
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| ¿µ¹® | antibody | ÇÑ±Û | Ç×ü |
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| ¼³¸í | »ç¶÷ÀÇ ¸ö¿¡¼ ¸é¿ª¿¡ °ü°èÇÏ´Â ¹°Áú. ¿ÜºÎ¿¡¼ µé¾î¿Â ¹°Áú°ú ²À ¸Â°Ô °áÇÕÀ» ÇÏ¿©¼ ±× ¹°ÁúÀÇ »ý¹°ÇÐÀû Ȱµ¿À» ¾ïÁ¦Çϰųª ÆÄ±«Çϰųª »ç¶÷ÀÇ ´Ù¸¥ ¸é¿ª¼¼Æ÷·Î ÇÏ¿©±Ý °ø°ÝÇϱ⠿ëÀÌÇÏ°Ô ÇØÁÖ´Â ±â´ÉÀ» °¡Áö°í ÀÖ´Ù. Ç×ü´Â ¸é¿ª±Û·ÎºÎ¸°À̶ó´Â °ÍÀ¸·Î ÀÌ·ç¾îÁ® ÀÖ°í ±× ÇüÅ¿¡ µû¶ó IgA, IgE, IgG, IgDµîÀ¸·Î ³ª´«´Ù. |
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| ADCC cell | Antibody Dependent Cellular(= Cell-Mediated) Cytotoxicity cell |
|---|---|
| LDCC | lectin-dependent cellular cytotoxicity |
| ADCC | acute disorder of cerebral circulation; antibody-dependent cell-mediated cytotoxicity |
| ADLC | antibody-dependent lymphocyte-mediated cytotoxicity |
| MICC | mitogen-induced cellular cytotoxicity |
| ADCC | Antibody Dependent Cellular Cytotoxicity |
|---|---|
| LDCC | Lectin-dependent cellular cytotoxicity |
| ADCC | Antibody Dependent Cell Cytotoxicity |
| ADCC | Antibody Dependent Cell-Mediated Cytotoxicity |
| ADCC | Antibody dependent Cytotoxicity |
| antibody-dependent cell cytotoxicity | The phenomenon of antibody-mediated target cell destruction by non-sensitised effector cells. The identity of the target cell varies, but it must possess surface IgG whose fc portion is intact. The effector cell is a "killer" cell possessing fc receptors. It may be a lymphocyte lacking conventional b- or T-cell markers, or a monocyte, macrophage, or polynuclear leukocyte, depending on the identity of the target cell. The reaction is complement-independent. (12 Dec 1998) |
|---|---|
| antibody-dependent enhancement | Enhancement of viral infectivity caused by non-neutralizing antibodies. There are at least two mechanisms known to account for this: mediation by fc receptors (receptors, fc) or by complement receptors (receptors, complement). Either the virus is complexed with antiviral IgG and binds to fc receptors, or virus is coated with antiviral IgM and binds to complement receptors. (12 Dec 1998) |
| cytotoxicity | The quality or state of being cytotoxic. Antibody-dependent cell-mediated cytotoxicity (ADCC), a form of lymphocyte-mediated cytotoxicity that functions only if antibodies are bound to the target cell. Lymphocyte-mediated cytotoxicity, the toxic or lytic activity of T-lymphocytes, which may or may not be mediated by antibodies. Cytotoxic T lymphocytes may cause lysis of cells by production of cytolytic proteins such as perforin. B-cells may cause lysis of cells by antibody-complement binding to a target cell. Natural killer cells are cytotoxic without prior sensitization. Toxicity by lymphocytes may also be mediated by antibodies; there are three kinds of cytotoxic T-lymphocytes: those that are antigen-specific as a result of previous allergization (immunization), killer cells, and natural killer cells. See: antibody-dependent cell-mediated cytotoxicity. (05 Mar 2000) |
| cytotoxicity, immunologic | The phenomenon of target cell destruction by immunologically active effector cells. It may be brought about directly by sensitised T-lymphocytes or by lymphoid or myeloid "killer" cells, or it may be mediated by cytotoxic antibody, cytotoxic factor released by lymphoid cells, or complement. (12 Dec 1998) |
| cytotoxicity tests, immunologic | The demonstration of the cytotoxic effect on a target cell of a lymphocyte, a mediator released by a sensitised lymphocyte, an antibody, or complement. (12 Dec 1998) |
| acute cellular rejection | Graft rejection which usually begins within 10 days after a graft has been transplanted into a genetically dissimilar host. Lesions at the site of the graft characteristically are infiltrated with large numbers of lymphocytes and macrophages which cause tissue damage. See: primary rejection. Synonym: acute rejection. (05 Mar 2000) |
| cellular | 1. Relating to, derived from, or composed of cells. 2. Having numerous compartments or interstices. Origin: L. Cellula, dim. Of cella, storeroom (05 Mar 2000) |
| cellular biology | <study> The study of cells. Implies the use of light or electron microscopic methods for the study of morphology. (18 Nov 1997) |
| cellular biophysics | Biophysics concerned with cellular processes. (05 Mar 2000) |
| cellular blue nevus | A large, acquired blue nevus in which melanocytes are often clear and large, alternating with pigmented spindle cells and which may expand deeply into the subcutis; malignant change is very rare. (05 Mar 2000) |
| cellular cartilage | An embryonic or immature stage of cartilage in which it consists chiefly of cells with very little matrix. Synonym: parenchymatous cartilage. (05 Mar 2000) |
| cellular embolism | Embolism due to a mass of cells transported from disintegrating tissue. (05 Mar 2000) |
| cellular engineering | <technique> The use of techniques for constructing replacement or additional or experimental parts of cells and tissues for both fundamental investigation and as prosthetic devices. Often involves the interfacing of cells and nonliving structures. (26 Mar 1998) |
| cellular immune theory | A concept, put forth by Elie Metchnikoff, that cells, not antibodies, were responsible for the immune response of an organism. (05 Mar 2000) |
| cellular immunity | <cell biology, immunology> Immune response that involves enhanced activity by phagocytic cells and does not imply lymphocyte involvement. Since the term is easily confused with cell-mediated immunity its use in this sense should be avoided. (26 Mar 1998) |
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