| AMA | 1) Anti-Mitochondrial Antibodies 2) American Medical Association |
|---|---|
| Anti-LKM | Antibodies to Liver-Kidney Microsome |
| FA | 1) Fatty Acid 2) Fluorescent Antibodies; Çü±¤ Ç×ü |
| MAbs | Monoclonal Antibodies |
| MHA-TP | Micro-Hemagglutination Assay for antibodies to Treponema Pallidum |
| AEA | A-anti-endomysium antibodies |
|---|---|
| ANCA | Anti-Neutrophil Cytoplasmic Antibodies |
| ACA | Anti-cardiolipin antibodies |
| ACL | Anti-cardiolipin antibodies |
| ACLA | Anti-cardiolipin antibodies |
| antibodies | Any of numerous protein molecules produced by the B-cells as a primary immune defense. (16 Dec 1997) |
|---|---|
| antibodies, anti-idiotypic | Antibodies which react with the individual structural determinants (idiotopes) on the variable region of other antibodies. (12 Dec 1998) |
| antibodies, anticardiolipin | Antiphospholipid antibodies found in association with systemic lupus erythematosus (lupus erythematosus, systemic), antiphospholipid syndrome, and in a variety of other diseases as well as in healthy individuals. The antibodies are detected by solid-phase immunoassay employing the purified phospholipid antigen cardiolipin. (12 Dec 1998) |
| antibodies, antineutrophil cytoplasmic | Autoantibodies directed against cytoplasmic constituents of polymorphonuclear leukocytes and/or monocytes. They are used as specific markers for wegener's granulomatosis and other diseases, though their pathophysiological role is not clear. Anca are routinely detected by indirect immunofluorescence with three different patterns: c-anca (cytoplasmic), p-anca (perinuclear), and atypical anca. (12 Dec 1998) |
| antibodies, antinuclear | See: Antinuclear antibodies. (12 Dec 1998) |
| antibodies, antiphospholipid | Autoantibodies directed against phospholipids. These antibodies are characteristically found in patients with systemic lupus erythematosus (lupus erythematosus, systemic), antiphospholipid syndrome, related autoimmune diseases, some non-autoimmune diseases, and also in healthy individuals. (12 Dec 1998) |
| antibodies, archaeal | Immunoglobulins induced by substances elaborated by archaea that have an antigenic activity. (12 Dec 1998) |
| antibodies, bacterial | Immunoglobulins induced by substances elaborated by bacteria that have an antigenic activity. (12 Dec 1998) |
| antibodies, bispecific | Antibodies, often monoclonal, in which the two antigen-binding sites are specific for separate antigenic determinants. They are artificial antibodies produced by chemical crosslinking, fusion of hybridoma cells, or by molecular genetic techniques. They function as the main mediators of targeted cellular cytotoxicity and have been shown to be efficient in the targeting of drugs, toxins, radiolabelled haptens, and effector cells to diseased tissue, primarily tumours. (12 Dec 1998) |
| antibodies, blocking | Antibodies that inhibit the reaction between antigen and other antibodies or sensitised T-lymphocytes (e.g., antibodies of the IgG class that compete with IgE antibodies for antigen, thereby blocking an allergic response). Blocking antibodies that bind tumours and prevent destruction of tumour cells by cytotoxic T-lymphocytes have also been called enhancing antibodies. (12 Dec 1998) |
| antibodies, catalytic | Antibodies that can catalyze a wide variety of chemical reactions. They are characterised by high substrate specificity and share many mechanistic features with enzymes. (12 Dec 1998) |
| antibodies, fungal | Immunoglobulins induced by substances elaborated by fungi that have an antigenic activity. (12 Dec 1998) |
| antibodies, helminth | Antibodies produced by human or animal cells following clinical or experimental exposure to parasitic helminth antigens. The IgE class of immunoglobulins is usually formed and released, but IgG, IgM, and IgA may also occur. (12 Dec 1998) |
| antibodies, heterophile | Antibodies elicited in a different species from which the antigen originated. These antibodies are directed against a wide variety of interspecies-specific antigens, the best known of which are forssman, hanganutziu-deicher (h-d), and paul-bunnell (p-b). Incidence of antibodies to these antigens--i.e., the phenomenon of heterophile antibody response--is useful in the serodiagnosis, pathogenesis, and prognosis of infection and latent infectious states as well as in cancer classification. (12 Dec 1998) |
| antibodies, monoclonal | Antibodies produced by clones of cells such as those isolated after hybridization of activated b lymphocytes with neoplastic cells. These hybrids are often referred to as hybridomas. (12 Dec 1998) |
| acetylcholine receptor antibodies | <neurology, investigation> A test used to measure the amount of antibodies to acetylcholine receptors on nerve endings. This is a diagnostic test for myasthenia gravis. A normal value is no antibodies in the bloodstream. Acetylcholine receptor (AChR) binding autoantibodies (i.e. Antibodies reactive with several epitopes other than the binding site for acetylcholine or alpha-bungarotoxin) are present in approximately 88% of patients with generalised myasthenia gravis, 70% of ocular myasthenia and in approximately 80% of myasthenia gravis in remission. Although serum concentrations of AChR binding autoantibodies do not in general correlate well with severity of weakness, there is typical decrease in concentration as weakness improves with immunosuppressive therapy. AChR blocking autoantibodies (i.e., antibodies reactive with the AChR binding site) are present in about 50% of patients with myasthenia gravis, 30% with ocular myasthenia gravis and 20% of myasthenia gravis in remission, AChR blocking autoantibodies are the only AChR autoantibodies present in about 1% of myasthenia gravis. AChR modulating autoantibodies (i.e., autoantibodies which cross-link AChRs and cause their removal from muscle membrane surfaces) are present in more than 90% of myasthenia gravis and occasionally are the only AchR autoantibodies detectable in mild, recent onset or ocular-restricted myasthenia gravis. Results for AChR modulating autoantibodies can be transiently false-positive due to curare-like drugs used during general anesthesia. AChR autoantibodies of one or more types are found in at least 80% of ocular myasthenia gravis. Although generally absent in neurological conditions other than myasthenia gravis(and consequently unlikely to cause confusion in neurodiagnosis), false-positive results for AChR autoantibodies occasionally occur in primary biliary cirrhosis, tardive dyskinesia, autoimmune thyroiditis, the elderly, amyotrophic lateral sclerosis patients treated with cobra venom and patients with thymoma in the absence of myasthenia gravis. Approximately 1% of patients with rheumatoid arthritis treated with D-penicillamine develop AChR autoantibodies and myasthenia gravis, both of which disappear when the drug is discontinued. Babies born to ~10% of myasthenia gravis mothers have a transient neonatal form of myasthenia gravis that responds well to anticholinesterase therapy and usually remits within 1 month as maternal IgG disappears. (29 Dec 1997) |
|---|---|
| anticardiolipin antibodies | <immunology> Antibodies directed against cardiolipid, a phosphorylated polysaccharide ester of fatty acids found in cell membranes. Associated with immune-mediated illnesses, syphilis, and strokes; thought to be from a hypercoagulable state. (05 Mar 2000) |
| anti-microsomal antibodies | Anti-microsomal antibodies or anti-thyroid microsomal antibodies measure for the presence of antibody to thyroid microsomes. The anti-microsomal antibody or microsomal antibody test is used to diagnose conditions such as Hashimoto's thyroiditis and other autoimmune disorders. (27 Sep 1997) |
| anti-mitochondrial antibodies | A special serologic test that measures the level of antibodies to a particular portion of a cell (mitochondria). (27 Sep 1997) |
| antiphospholipid antibodies | Antibodies directed against phosphorylated polysaccharide esters of fatty acids, includes lupus anticoagulant, VDRL, and anticardiolipin antibodies. Associated with immune-mediated illnesses, syphilis, and stroke; thought to be from a hypercoagulable disorder. (05 Mar 2000) |
| antisperm antibodies | <immunology> Antibodies that can attack sperm and inhibit their movement or block fertilization of the egg. (13 Jan 1998) |
| antithyroid microsomal antibodies | <immunology> Anti-microsomal antibodies or anti-thyroid microsomal antibodies measure for the presence of antibody to thyroid microsomes. (13 Jan 1998) |
| chimeric antibodies | Antibodies that may have the FAB fragment from one species fused with FC fragment from another. (05 Mar 2000) |
| monoclonal antibodies | Identical antibodies that are made in large amounts in the laboratory. Doctors are studying ways of using monoclonal antibodies to treat leukaemia. (12 Dec 1998) |
| P-K antibodies | IgE antibodies involved in the Prausnitz-Kustner reaction. (05 Mar 2000) |
| polyclonal antibodies | A group of antibodiesproduced by different B lymphocytes in responseto the same antigen, different antibodies in the group recognise different parts of the antigen. (09 Oct 1997) |
| hepatitis antibodies | Immunoglobulins raised by any form of viral hepatitis; some of these antibodies are used to diagnose the specific kind of hepatitis. (12 Dec 1998) |
| hepatitis B antibodies | <immunology> Antibodies to the hepatitis b antigens, including antibodies to the surface (Australia) and core of the dane particle and those to the "e" antigens. (12 Dec 1998) |
| hepatitis c antibodies | Antibodies to the hepatitis c antigens including antibodies to envelope, core, and non-structural proteins. (12 Dec 1998) |
| HIV antibodies | Antibodies reactive with human immunodeficiency virus (HIV, previously called HTLV-III/lav) antigens of aids. This includes HIV-1 antibodies and HIV-2 antibodies. (12 Dec 1998) |
Synonyms :
Synonyms : Anti Antibodies, Anti-gamma Globulin Antibodies, Anti Idiotype Antibodies, Anti gamma Globulin Antibodies, Anti-Idiotypic Antibodies, Antibodies, Anti, Antibodies, Anti Idiotypic, Antibodies, Anti-Idiotype, Antibodies, Anti-gamma Globulin
Synonyms : Anticardiolipin Antibody, Antibody, Anticardiolipin
Synonyms : Anti-Neutrophil Cytoplasmic Antibodies, Anti-Neutrophil Cytoplasmic Antibody, Antineutrophil Cytoplasmic Antibody, Anti Neutrophil Cytoplasmic Antibodies, Anti Neutrophil Cytoplasmic Antibody, Antibodies, Anti-Neutrophil Cytoplasmic, c ANCA, p ANCA
Synonyms : Antinuclear Antibody, Antinuclear Factor, Anti DNA Antibodies, Antibodies, Anti DNA, Antibodies, Fluorescent Antinuclear, Antibody, Antinuclear, Antinuclear Antibodies, Fluorescent, Factor, Antinuclear, Factors, Antinuclear
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