| 영문 | aging, senescence | 한글 | 노화, 늙음 |
|---|---|---|---|
| 설명 | 나이 먹는다는 의미로 사용되기도 하지만 일반적으로는 성장이 완료, 정지되고 그 이후에 일어나는 모든 과정을 가리킨다. 나이를 먹어감에 따라 생체의 여러 가지 기능이 저하되는데, 일반적으로 세포에 색소가 축적되거나 세포자체나 핵이 작아지는 현상이다. 개개의 세포 기능도 저하되고, 세포 내에 색소가 침착되며, 기관은 암갈색을 띤다. 또한 피부는 얇아지고 털주머니도 위축되며, 모발은 색소를 잃고 탈모된다. 현재 많은 학자들은 세포내 DNA가 끊어지거나 끊어진 경우 수복력이 감소하거나, 면역력이 저하하기 때문으로 보고 있다. 노화가 일어나는 것은 세포의 종류에 따라서 크게 다른데 신경세포처럼 태어나서 죽을 때까지 세포분열하지 않는 세포는 노화가 두드러지고 고환이나 골수의 세포처럼 항상 분열하는 세포는 노화현상이 거의 일어나지 않는다. 발병과 죽음의 확률이 높아지지만, 노쇠성 변화와 병적 변화와의 경제는 명확하지 않다. 노쇠를 야기하는 노화의 본질적 원인에 대해서는 아직 정설이 없다. |
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| 영문 | amyloidosis | 한글 | 아밀로이드증 |
|---|---|---|---|
| 설명 | 본래 생체에는 없는 당단백질의 일종으로 비정상적으로 아밀로이드단백이 조직이나 장기에 침착되는 병. 발현부위가 전신성인 경우의 아밀로이드증(전신성 아밀로이드증)에는 명백한 원인없이 일어나는 원발성 아밀로드증과 만성화농성 염증이나 결핵 등 소모성 질환에서 찾아볼 수 있는 속발성 아밀로이드증이 있다. 발현부위가 국소성인 경우의 국소성 아밀로이드증으로서는 뇌의 노인반이 그 예이며, 특히 입안에서는 혀나 잇몸에 대한 침착이 현저하고 여러 가지 기능장애를 나타낸다. 조직학적으로는 헤마톡실린 에오진염색에서는 에오진성 무구조인 유리화를 나타내며 콩고레드, 편광상(녹색) 등으로 확인한다. 구조적으로는 아밀로이드 섬유의 집합으로 이루어지는 여러 가지 아밀로이드 침착이 있으며 그것들에 대한 병형이 분류되어 있다. 가족형, 다발성 골수종과 수반하는 형 그리고 가족성 지중해열을 수반하는 형 등이 있다. |
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| AL | absolute latency; acinar lumen; acute leukemia; adaptation level; albumin; alcoholism [and other dru... |
|---|---|
| DAA | decompensated autonomous adenoma; dementia associated with alcoholism; dialysis-associated amyloidos... |
| HCHWA | hereditary cerebral hemorrhage with amyloidosis |
| AAA | abdominal aortic aneurysm/aneurysmectomy; acne-associated arthritis; acquired aplastic anemia; acute... |
| AAHA | American Academy of Hospital Attorneys; American Association of Homes for the Aging |
| AL | Amyloidosis |
|---|---|
| BLSA | Baltimore Longitudinal Study of Aging |
| CSHA | Canadian Study of Health and Aging |
| DRA | Dialysis related amyloidosis |
| FAF | Familial amyloidosis, Finnish type |
| aging | The gradual changes in the structure and function of humans and animals that occur with the passage of time, that do not result from disease or other gross accidents, and that eventually lead to the increased probability of death as the person or animal grows older. It does not apply to microorganisms. (12 Dec 1998) |
|---|---|
| aging, premature | Changes in the organism associated with senescence, occurring at an accelerated rate. (12 Dec 1998) |
| cell aging | The decrease in the cell's ability to proliferate with the passing of time. Each cell is programmed for a certain number of cell divisions and at the end of that time proliferation halts. The cell enters a quiescent state after which it experiences cell death via the process of apoptosis. (12 Dec 1998) |
| clonal aging | The deterioration in successive generations of a clone; thus paramecia and other simple forms, if allowed to reproduce asexually for a number of generations, invariably undergo deterioration, the characters of each group of descendants progressively departing from those of the original sexually produced ancestor. (05 Mar 2000) |
| skin aging | The process of aging due to changes in the structure and elasticity of the skin over time. It may be a part of physiological aging or it may be due to the effects of ultraviolet radiation, usually through exposure to sunlight. (12 Dec 1998) |
| erythrocyte aging | Senescence of the red blood cell. Lacking the organelles that make protein synthesis possible, the mature erythrocyte is incapable of self-repair, reproduction, and carrying out certain functions performed by other cells. This limits the average life span of an erythrocyte to 120 days. (12 Dec 1998) |
| amyloidosis | Deposition of amyloid. A common complication of several diseases (leprosy, tuberculosis), often associated with perturbation of the immune system, although there may be immunosuppression or enhancement. (18 Nov 1997) |
| amyloidosis: bone manifestations | <radiology> Joint pain without radiographic findings, osteoporosis, especially in axial skeleton, lytic lesions that destroy cortex and invade soft tissue, wrist, scaphoid and lunate lesions that may extend into the carpal tunnel, inducing the classic complaints of carpal tunnel syndrome amyloid arthropathy Differential diagnosis: pigmented villonodular synovitis, synovial chondromatosis, rheumatoid arthritis, TB (12 Dec 1998) |
| amyloidosis cutis | Localised cutaneous amyloidosis with pruritic brownish-red papules, most commonly on the lower legs, due to amyloid infiltration of the papillary dermis. Synonym: amyloidosis cutis, lichen amyloidosis. Origin: G. Leichen, lichen, a lichen-like eruption + eidos, resemblance (05 Mar 2000) |
| amyloidosis: gastrointestinal manifestations | <radiology> Oesophagus, loss of peristalsis, megaesophagus, stomach, small and rigid (simulate linitis plastica), effaced rugal pattern, diminished/absent peristalsis, may be localised to antrum, amyloidoma: well defined submucosal mass, small bowel, diffuse form (more common), diffuse, uniform thickening of valvulae conniventes, broadened flat undulated mucosal folds (mucosal atrophy), jejunalization of ileum, impaired motility, small bowel dilatation, localised form: multiple small deposits; associated with pseudoobstruction, colon, psudopolyps (12 Dec 1998) |
| amyloidosis of multiple myeloma | Foci of amyloidosis in mesenchymal tissues of some persons with multiple myeloma; no direct relation between amyloid and Bence Jones protein is conclusively known. (05 Mar 2000) |
| macular amyloidosis | A localised form of amyloidosis cutis characterised by pruritic symmetrical brown reticulated macules, especially on the upper back; microscopically, amyloid is deposited as small subepidermal globules. (05 Mar 2000) |
| renal amyloidosis | Renal deposits of amyloid, especially in glomerular capillary walls, which may cause albuminuria and the nephrotic syndrome. Synonym: amyloid nephrosis. (05 Mar 2000) |
| cerebral amyloidosis | A condition where there is a deposition of amyloid (insoluble protein) in the walls of the arteries which supply the brain. This results in an increased risk of dementia and-or intracerebral haemorrhage. Cerebral amyloidosis or cerebral amyloid angiopathy, is a complication of primary amyloidosis. (27 Sep 1997) |
| primary amyloidosis | <immunology, nephrology> A disease which is characterised by the deposition of the fibrous protein amyloid in one or more locations within the body. Amyloid deposition may occur in the kidney, brain, liver, heart, skin and lungs. A recognised complication is a restrictive cardiomyopathy. (05 Mar 1998) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|