| amidophosphoribosyltransferase | <enzyme> An enzyme, involved in the early steps of purine nucleotide biosynthesis, that catalyses the formation of 5-phosphoribosylamine from glutamine and phosphoribosylpyrophosphate. Chemical name: 5-Phosphoribosylamine:pyrophosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating) Registry number: EC 2.4.2.14 (12 Dec 1998) |
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Synonyms : Glutamine-Amidophosphoribosyltransferase, Phosphoribosyldiphosphate 5-Amidotransferase, 5-Amidotransferase, Phosphoribosyldiphosphate, Amidotransferase, Phosphoribosyl Pyrophosphate, Glutamine Amidophosphoribosyltransferase
| amidophosphoribosyltransferase |
[EC 2.4.2.14] an enzyme of the transferase class that catalyzes the first committed step in purine nucleotide biosynthesis, the transfer of an amino group to phosphoribosylpyrophosphate from glutamine, forming phosphoribosylamine as well as glutamate and pyrophosphate. The reaction is inhibited by purine nucleotides.
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