| allostery | A phenomenon in which a small ligand binds to a receptor site ona protein, changes the shape of the protein and thus changes the specificityof a second site (either anotherreceptor or an enzyme activesite) on that protein. (09 Oct 1997) |
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| allostery |
the condition in which the binding of a substrate, product, or other effector to a subunit of a multi-subunit enzyme or other protein at a site (allosteric site) other than the functional site alters its conformation and functional properties, such as by affecting binding of other ligands at the functional site (cooperativity).
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