| 영문 | aldosterone | 한글 | 알도스테론 |
|---|---|---|---|
| 설명 | 콩팥 위에 있는 작은 삼각형의 기관인 부신의 겉질에서 분비되는 호르몬. 체내의 물과 전해질의 균형에 기여한다. 신장에 작용해서 물과 나트륨의 흡수를 촉진하고 칼륨을 분비하게 한다. 즉 이 호르몬의 작용에 의하여 체내의 물과 나트륨의 양은 증가하고 칼륨의 양은 감소한다. 콩팥에서 혈류와 혈압을 감지하는 세포인 치밀반점(macula densa)과 토리곁세포(JG Cell)에서 혈류와 혈압의 저하가 있을 경우에 레닌(renin)이라는 물질이 분비된다. 이 레닌이라는 물질은 혈중에 존재하는 안지오텐시노겐이라는 물질을 안지오텐신 I으로 변화시키고 이 물질은 안지오텐신 I 전환효소에 의해서 안지오텐신 II라는 물질로 된다. 이 물질은 강력하게 혈관을 수축시키고 이로 인해서 혈압이 올라가는 동시에 부신을 자극하여 알도스테론을 분비하게 한다. 이 레닌-안지오텐신-살도스테론의 체계는 몸속의 혈압이 떨어지거나 혈액의 양이 줄어드는 경우에 작용해서 혈압을 올리는 작용을 한다.  |
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| RAA | Renin-Angiotensin-Aldosterone |
|---|---|
| AER | abduction/external rotation; acoustic evoked response; acute exertional rhabdomyolysis; agranular en... |
| AIP | acute idiopathic pericarditis; acute infectious polyneuritis; acute intermittent porphyria; aldoster... |
| Aldo, ALDOST | aldosterone |
| APA | action potential amplitude; aldosterone-producing adenoma; Ambulatory Pediatric Association; America... |
| CCA | Calcium channel antagonists |
|---|---|
| H(2)RA | H(2) receptor antagonists |
| LTRA | Leukotriene receptor antagonists |
| AIIRA | angiotensin II receptor antagonists |
| A | Aldosterone |
| aldosterone antagonists | Compounds which inhibit or antagonise the biosynthesis or actions of aldosterone. (12 Dec 1998) |
|---|
| aldosterone | <endocrinology, hormone> A steroid hormone produced by the adrenal cortex, that controls salt and water balance in the kidney. Abnormally high levels of this hormone cause sodium retention, high blood pressure, heart rhythum irregularities and possibly paralysis (18 Nov 1997) |
|---|---|
| aldosterone antagonist | An agent that opposes the action of the adrenal hormone aldosterone on renal tubular mineralocorticoid retention; these agents, e.g., spironolactone, are useful in treating the hypertension of primary hyperaldosteronism, or the sodium retention of secondary hyperaldosteronism. (05 Mar 2000) |
| receptors, aldosterone | Cytoplasmic proteins that specifically bind aldosterone and mediate its cellular effects. The aldosterone-bound receptor acts in the nucleus to regulate the transcription of specific segments of DNA. (12 Dec 1998) |
| renin-angiotensin-aldosterone system | The hormones, renin, angiotensin, and aldosterone work together to regulate blood pressure. A sustained fall in blood pressure causes the kidney to release renin. This is converted to angiotensin in the circulation. Angiotensin then raises blood pressure directly by arteriolar constriction and stimulates adrenal gland to produce aldosterone which promotes sodium and water retention by kidney, such that blood volume and blood pressure increase. (05 Mar 2000) |
| hormone, aldosterone | Hormone produced by the outer portion (cortex) of the adrenal gland that regulates the balance of water and electrolytes (ions such as potassium and sodium) in the body. Aldosterone encourages the kidney to excrete potassium into the urine and to retain sodium, thereby retaining water. Aldosterone is classified as a mineralocorticoid hormone. (12 Dec 1998) |
| adrenergic alpha-antagonists | Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. (12 Dec 1998) |
| adrenergic antagonists | Drugs that bind to but do not activate adrenergic receptors. Adrenergic antagonists block the actions of the endogenous adrenergic transmitters epinephrine and norepinephrine. (12 Dec 1998) |
| adrenergic beta-antagonists | Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrythmias, angina pectoris, glaucoma, migraine headaches, and anxiety. (12 Dec 1998) |
| androgen antagonists | Compounds which inhibit or antagonise the biosynthesis or actions of androgens. (12 Dec 1998) |
| gaba antagonists | Drugs that bind to but do not activate gaba receptors, thereby blocking the actions of endogenous gaba or gaba agonists. (12 Dec 1998) |
| cholinergic antagonists | Drugs that bind to but do not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists. (12 Dec 1998) |
| muscarinic antagonists | Drugs that bind to but do not activate muscarinic cholinergic receptors (receptors, muscarinic), thereby blocking the actions of endogenous acetycholine or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system. Antagonists that discriminate among the various muscarinic receptor subtypes and might allow better control of peripheral and central actions are under development. (12 Dec 1998) |
| heparin antagonists | Coagulant substances inhibiting the anticoagulant action of heparin. (12 Dec 1998) |
| prostaglandin antagonists | Compounds that inhibit the action of prostaglandins. (12 Dec 1998) |
| histamine antagonists | Drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonist. Classical antihistaminics block the histamine h1 receptors only. (12 Dec 1998) |
Synonyms : Antagonists, Aldosterone
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|