| ¿µ¹® | alcohol | ÇÑ±Û | ¾ËÄÚ¿Ã |
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| ¼³¸í | ´ë°³ ¿¡Åº¿Ã(ethanol, ethyl alcohol)À» ÁöĪÇÏ´Â ¸»ÀÌ´Ù. ¹°°ú °°ÀÌ ¸¼Àº »öÀÌÁö¸¸ ƯÀÌÇÑ ³¿»õ°¡ ÀÖ°í ²ú´Â Á¡ÀÌ ³·Àº ¾×üÀÌ´Ù. ³óµµ°¡ ³ôÀº °ÍÀº ÀÇ·á¿ë ¶Ç´Â ¼Òµ¶Á¦·Î ¾²ÀÌ°í ³·Àº ³óµµ·Î µÈ °ÍÀº À½·á(¼ú)·Îµµ ÀÌ¿ëµÈ´Ù. |
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| ¿µ¹® | ethyl alcohol | ÇÑ±Û | ¿¡Æ¿¾ËÄÚ¿Ã |
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| ¼³¸í | Áö¹æÁ· Æ÷ȾËÄÚ¿ÃÀÇ Çϳª. °¢Á¾ ¾ËÄÚ¿Ã À½·á ¼Ó¿¡ ÇÔÀ¯µÇ¾î ÀÖ¾î ÁÖÁ¤À̶ó°íµµ Çϰí, ¶Ç ¿¡Åº¿ÃÀ̶ó°íµµ ÇÑ´Ù. º¸Åë ¾ËÄÚ¿ÃÀ̶ó°í Çϸé ÀÌ ¿¡Æ¿¾ËÄÚ¿ÃÀ» °¡¸®Å²´Ù. ¼úÀÇ ¼ººÐÀ¸·Î¼ ¿¹ÀüºÎÅÍ ¾Ë·ÁÁ® ÀÖ¾úÀ¸³ª, ¼úÀÌ ÃëÇÏ´Â ¿øÀÎÀÌ ¿¡Åº¿Ã¿¡ ÀÖ´Ù´Â °ÍÀ» ¾È °ÍÀº 15¼¼±â ÀÌÈÄÀÇ ÀÏÀÌ´Ù. Á¶¼ºÀº óÀ½¿¡ ¶óºÎ¾ÆÁö¿¡³ª N.T. ¼Ò½´¸£ µî¿¡ ÀÇÇØ ÃøÁ¤µÇ°í, °ÔÀÌ·ò»èÀ̳ª J.B. µÚ¸¶ µî¿¡ ÀÇÇØ¼ È®Á¤µÇ¾ú´Ù. ¾ËÄÚ¿ÃÀ̶ó´Â À̸§Àº ¿ø·¡ ´«½ç¿¡ Ä¥ÇÏ´Â Èæ»ö ¾È·áäÔÖù¸¦ °¡¸®Å°´Â ¾Æ¶óºñ¾Æ¾î¿´´Âµ¥. À̰ÍÀÇ ¹Ì¼ÒºÐ¸»À» ¸¸µå´Âµ¥ ½ÂȹýÀ» »ç¿ëÇÑ µ¥¼ ¼úÀ» Áõ·ùÇÏ¿© °¡¿¬¼º ¿¢½º¸¦ ¸¸µå´Â °ÍÀ¸·Î ÀüÈï®ûùÇϰí, À̰ÍÀÌ ´Ù½Ã Áõ·ù¹°À» °¡¸®Å°´Â ¸»ÀÌ µÇ¾ú´Ù. ¾ËÄÚ¿ÃÀ̶ó´Â ¸»ÀÌ ¿¡Åº¿ÃÀ» °¡¸®Å°°Ô µÇ°í, ´Ù½Ã ¾ËÄÚ¿Ã Àü¹ÝÀ» °¡¸®Å°°Ô µÈ °ÍÀº 19¼¼±â ÀÌÈÄÀÇ ÀÏÀÌ´Ù. ¿¡Åº¿ÃÀ» º¹¿ëÇÏ¸é ´ë³úÀÇ Á¦¾î±â´ÉÀÌ ¾ïÁ¦µÇ¾î ÈïºÐ»óŰ¡ µÇ°í, ÀÌ¾î¼ ÁßÃ߽ŰæÀÌ ¾ïÁ¦µÈ´Ù. ¹«»öÅõ¸íÇÑ Èֹ߼º ¾×ü. ƯÀ¯ÇÑ ³¿»õ¿Í ¸ÀÀ» °¡Áö¸ç, ÀÎü¿¡ Èí¼öµÇ¸é ÈïºÐÀ̳ª ¸¶Ãë ÀÛ¿ëÀ» ÀÏÀ¸Å²´Ù. ÈÇоàǰÀÇ ÇÕ¼º ¿ø·á, ¿ëÁ¦, ¿¬·á, ¾ËÄڿüº À½·á µûÀ§·Î ¾´´Ù. ¾ËÄÚ¿ÃÀº °£¼¼Æ÷¿¡ Á¸ÀçÇÏ´Â ¾ËÄÚ¿ÃÅ»¼ö¼ÒÈ¿¼Ò(alcohol dehydrogenase)°¡ ´ë»çÇÑ´Ù. ±Þ¼º Áßµ¶ Áõ»óÀº Ç÷Áß ¾ËÄÚ¿Ã ³óµµ¿Í ºñ·ÊÇÑ´Ù. Ç÷Áß ¾ËÄÚ¿Ã ³óµµ°¡ ³ô¾ÆÁú¼ö·Ï ÁßÃ߽Űæ°è´Â ¾ïÁ¦µÇ¾î Ç÷Áß ³óµµ°¡ 3.5~4.5mg/mLÀ̸é È¥¼ö¿¡ ºüÁ® »ç¸ÁÇÒ ¼öµµ ÀÖ´Ù. |
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| ¿µ¹® | fetal alcohol syndrome | ÇÑ±Û | žƾËÄÚ¿ÃÁõÈıº |
|---|---|---|---|
| ¼³¸í | ÀӽűⰣ Áß ¸¸¼ºÀûÀ¸·Î ¾ËÄÚ¿ÃÀ» ¼·ÃëÇÑ ¿©ÀÚ¿¡°Ô¼ ÅÂ¾î³ ¿µ¾Æ¿¡°Ô ³ªÅ¸³ª´Â ÇüŹ߻ýÀÇ ÀÌ»óÀ» ³ªÅ¸³»´Â ÁõÈıºÀ¸·Î¼ À§ÅλÀ¹ßÀ°ºÎÀü, ¾Õ¸Ó¸®¿Í ¾Æ·¡ÅÎÀÇ µ¹Ãâ, ªÀº°Ë¿, ÀÛÀº¾È±¸Áõ, ´«±¸¼®ÁÖ¸§, ½ÉÇÑ ¼ºÀåÁö¿¬, Á¤½ÅÁöü µîÀ» ³ªÅ¸³½´Ù. |
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| NDMA | nitrosodimethylamine |
|---|---|
| NMOR | nemadione oxidoreductase; N-nitrosomorpholine |
| NQO | NAD(P)H:quinone oxidoreductase |
| AA/AD | alcohol abuse/alcohol dependence |
| ADS | Alcohol Dependence Syndrome |
| NDMA | N-Nitroso-dimethylamine |
|---|---|
| NDMA-D | nitrosodimethylamine demethylase |
| 17 beta-HSOR | 17 beta-Hydroxysteroid oxidoreductase |
| 3 alpha-HSOR | 3 alpha-Hydroxysteroid oxidoreductase |
| ETF-QO | Electron transfer flavoprotein-ubiquinone oxidoreductase |
| alcohol - NDMA oxidoreductase | <enzyme> Nicotinoprotein from amycolatopsis methanolica; does not react with exogenous NADP(h) Registry number: EC 1.1.99.- Synonym: 4-nitroso-n,n-dimethylaniline alcohol oxidoreductase, ndma-adh (26 Jun 1999) |
|---|
| acyclic monoterpene primary alcohol - NADP oxidoreductase | <enzyme> From catmint nepeta racemosa; involved in the biosynthesis of iridoid monoterpenes; oxidises geraniol, nerol, and their 10-hydroxy derivatives in the presence of nadp(+). Registry number: EC 1.1.1.- Synonym: monoterpene primary alcohol - nadp oxidoreductase, ampano (26 Jun 1999) |
|---|---|
| alcohol - N, N'-dimethyl-4-nitrosoaniline oxidoreductase | <enzyme> A group III alcohol oxidoreductase from rhodococcus sp, amycolatopsis methanolica and mycobacterium gastri; genbank u21071 Registry number: EC 1.1.99.- Synonym: thce gene product, thce protein, methanol - ndma oxidoreductase (26 Jun 1999) |
| acetoin-2,6-dichlorophenolindophenol oxidoreductase | <enzyme> Enzyme from the anaerobe pelobacter carbinolicus; catalyses thiamine pyrophosphate dependent oxidative-hydrolytic cleavage of acetoin, methylacetoin or diacetylacetoin to form acetic acid plus acetaldehyde, acetone or 2-acetic acid, respectively Registry number: EC 1.2.99.- Synonym: aodcpip oxidoreductase (26 Jun 1999) |
| acyl dihydroxyacetone phosphate oxidoreductase | <enzyme> Forms acyl-sn-glycerol 3-phosphate; uses NADPH Registry number: EC 1.1.1.- (26 Jun 1999) |
| aldehyde ferredoxin oxidoreductase | <enzyme> Contains molybdopterin as the organic component of tungsten cofactor Registry number: EC 1.2.7.- (26 Jun 1999) |
| alkyl dihydroxyacetone phosphate oxidoreductase | <enzyme> Forms alkyl-sn-glycerol 3-phosphate, uses NADPH Registry number: EC 1.1.1.- (26 Jun 1999) |
| androstenedione 17-alpha-oxidoreductase | <enzyme> Forms epitestosterone; was mapped to testosterone dehydrogenases (85-93); index medicus see under 17-hydroxysteroid dehydrogenases (85-90) Registry number: EC 1.1.1.- Synonym: steroid 17alpha oxidoreductase, androstenedione 17-oxidoreductase (26 Jun 1999) |
| benzoyl-coenzyme A-4-oxidoreductase | <enzyme> Acts on an aromatic ch-ch bond; catalyses the conversion of 4-hydroxybenzoyl-CoA to benzoyl-CoA Registry number: EC 1.3.99.- Synonym: benzoyl-CoA-4-oxidoreductase, 4-hydroxybenzoyl-CoA reductase (dehydroxylating), hbab gene product, hbac gene product, hbad gene product (26 Jun 1999) |
| benzylviologen-linked aldehyde oxidoreductase | <enzyme> A coenzyme a-independent tungsten-containing aldehyde oxidoreductase; from desulfovibrio gigas; n-terminal amino acid sequence given in first source Registry number: EC 1.2.7.- Synonym: bv-aldh (26 Jun 1999) |
| carbon monoxide-methylene blue oxidoreductase | <enzyme> Molybdenum-containing iron-sulfur flavoprotein from pseudomonas carboxydovorans; forms carbon dioxide Registry number: EC 1.2.3.- Synonym: cm-mb oxidoreductase, carbon monoxide oxidase (26 Jun 1999) |
| mannitol - mannose 1-oxidoreductase | <enzyme> Isolated from celeriae root tips; catalyses the nad-dependent oxidation of mannitol to mannose not to fructose; strongly inhibited by NADH and sensitive to alterations of nad-NADH ratio. Do not confuse with mannitol dehydrogenase (EC 1.1.1.67) which is a 2-oxidoreductase which converts mannitol to fructose Registry number: EC 1.1.1.- Synonym: mannitol 1-dehydrogenase (26 Jun 1999) |
| CDP-glucose oxidoreductase | <enzyme> From yersinia pseudotuberculosis; nad+-dependent; forms cdp-4-keto-6-deoxy-d-glucose Registry number: EC 1.1.1.- (26 Jun 1999) |
| p-cresol oxidoreductase | <enzyme> Catalyses hydroxylation of methyl group Registry number: EC 1.14.- Synonym: flavochrome p-cresol methylhydrolase (26 Jun 1999) |
| glucose-1-fructose-2-oxidoreductase | <enzyme> Catalyses intermolecular oxidation-reduction of glucose and fructose to form gluconolactone and sorbitol; contains tightly bound nadp as h+ carrier; does not require added cofactor Registry number: EC 1.1.1.- (26 Jun 1999) |
| glucose-fructose oxidoreductase | <enzyme> Isolated from zymomonas mobilis; catalyses the formation of sorbitol and glucono-delta-lactone from glucose and fructose; enzyme contains tightly bound nadp+ Registry number: EC 1.1.99.- (26 Jun 1999) |
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