| agglutinins | Substances, usually of biological origin, that cause cells or other organic particles to aggregate and stick to each other. They also include those antibodies which cause aggregation or agglutination of a particulate or insoluble antigen. (12 Dec 1998) |
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| warm agglutinins | Antibody that reacts with an antigen that is a normal component of the body. Obviously this can lead to some problems and autoimmunity has been proposed as a causative factor in a number of diseases such as rheumatoid arthritis. See: systemic lupus erythematosus, Hashimoto's thyroiditis, myasthenia gravis. (18 Nov 1997) |
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| cold agglutinins | <haematology> Antibodies that agglutinate particles with greater activity below 32C. They are IgM antibodies specifically reactive with blood groups I and i in humans and agglutinate red blood cells on cooling, causing Raynaud's phenomenon in vivo. (18 Nov 1997) |
| wheat germ agglutinins | Lectins purified from the germinating seeds of common wheat (triticum vulgare); these bind to certain carbohydrate moieties on cell surface glycoproteins and are used to identify certain cell populations and inhibit or promote some immunological or physiological activities. There are at least two isoforms of this lectin. (12 Dec 1998) |
| febrile agglutinins | <investigation> A serologic fluorescent antibody screen that indicates infection with the rickettsial bacteria which is responsible for Rocky Mountain spotted fever. This test may also be positive in brucellosis, salmonella infection and tularaemia. (27 Sep 1997) |
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