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| AML | Acute Myelogenous Leukemia Morphologic Classification(FABºÐ·ù) &n... |
|---|---|
| E0 | electric affinity |
| EA | early antigen; educational age; egg albumin; electric affinity; electrical activity; electroacupunct... |
| EAQ | eudismic affinity quotient |
| HAChT | high affinity choline transport |
| GMF | Glia Maturation Factor |
|---|---|
| IVM | In vitro maturation |
| MI | Maturation Index |
| MPF | Maturation Promoting Factor |
| MV | Maturation Value |
| maturation | 1. Achievement of full development or growth. 2. Developmental changes that lead to maturity. 3. Processing of a macromolecule; e.g., posttranscriptional modification of RNA or posttranslational modification of proteins. Origin: L. Maturatio, a ripening, fr. Maturus, ripe (05 Mar 2000) |
|---|---|
| maturation arrest | Cessation of complete differentiation of cells at an immature stage; in spermatogenic maturation arrest, the seminiferous tubules contain spermatocytes, but no spermatozoa develop. (05 Mar 2000) |
| maturation factor | <biochemistry> Member of the water soluble B vitamin group, important in the proper function of the nervous system and important in proper carbohydrate, protein and fat metabolism. (27 Sep 1997) |
| maturation index | An index indicating the degree of maturation attained by the vaginal epithelium as adjudged by the cell types being exfoliated; serves as an objective means of evaluating hormonal secretion or response; represents the percentage of parabasal cells/intermediate cells/superficials, in that order; "shift to the left" indicates more immature cells on the surface (atrophy), while "shift to the right" indicates more mature epithelium. (05 Mar 2000) |
| maturation-promoting factor | <enzyme> A protein kinase that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by cyclins, maturation-promoting factor directly phosphorylates some of the proteins involved in nuclear envelope breakdown, chromosome condensation, spindle assembly, and the degradation of cyclins. The catalytic subunit of maturation-promoting factor is protein p34cdc2. Acronym: MPF (12 Dec 1998) |
| maturation value | An indicator of the level of maturation attained by vaginal epithelium and used as a factor in cytohormonal evaluation from the maturation index by valuing the parabasal cells at 0.0, the intermediate cells at 0.5, and the superficial cells at 1.0; for special investigations, subtypes of a major cell can be given different values's. (05 Mar 2000) |
| sex maturation | Achievement of full sexual capacity. Applies to animals and humans. (12 Dec 1998) |
| sperm maturation | Posttesticular ripening of spermatozoa. (12 Dec 1998) |
| erythrocyte maturation factor | <biochemistry> Member of the water soluble B vitamin group, important in the proper function of the nervous system and important in proper carbohydrate, protein and fat metabolism. (27 Sep 1997) |
| affinity | 1. An inherent likeness or relationship. 2. A special attraction for a specific element, organ or structure. 3. <chemistry> The force that binds atoms in molecules, the tendency of substances to combine by chemical reaction. 4. The strength of noncovalent chemical binding between two substances as measured by the dissociation constant of the complex. 5. <immunology> A thermodynamic expression of the strength of interaction between a single antigen binding site and a single antigenic determinant (and thus of the stereochemical compatibility between them), most accurately applied to interactions among simple, uniform antigenic determinants such as haptens. Expressed as the association constant (K litres mole 1), which, owing to the heterogeneity of affinities in a population of antibody molecules of a given specificity, actually represents an average value (mean intrinsic association constant). 6. <chemistry> The reciprocal of the dissociation constant. Origin: L. Affinitas = relationship (06 Oct 1997) |
| affinity adsorbent | <immunology> A support matrix coated with an affinity antibodies. (06 May 1997) |
| affinity antibody | The measure of the interaction between molecules such as a receptor and its ligand. This interaction is reversible. (05 Mar 2000) |
| affinity chromatography | <investigation> A technique of analytical chemistry used to separate and purify a biological molecule from a mixture, based on the attraction of the molecule of interest to a particular ligand which has been previously attached to a solid, inert substance. The mixture is passed through a column containing the ligand attached to the stationary substance, so that the molecule of interest stays within the column while the rest of the mixture continues through to the end. Then, a different chemical is flushed through the column to detach the molecule from the ligand and bring it out separately from the rest of the mixture. (09 Feb 1998) |
| affinity column | <investigation> A technique of analytical chemistry used to separate and purify a biological molecule from a mixture, based on the attraction of the molecule of interest to a particular ligand which has been previously attached to a solid, inert substance. The mixture is passed through a column containing the ligand attached to the stationary substance, so that the molecule of interest stays within the column while the rest of the mixture continues through to the end. Then, a different chemical is flushed through the column to detach the molecule from the ligand and bring it out separately from the rest of the mixture. (09 Feb 1998) |
| affinity labeling | <technique> A method for tagging molecules, such as enzymes, so that they can be more easily detected and studied. The method works by substituting a synthetic substance which is similar to the substance that the enzyme normally bonds with. (09 Feb 1998) |
| affinity maturation |
The mechanism during an immune response that produces antibodies with a strong ability to bind to a foreign antigen over time. Affinity maturation is produced by changes in the genes that encode immunoglobulin G (IgG) and by
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