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ECG Electro-Cardio-Graphy(-Gram); ½ÉÀüµµ
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ACM acetaminophen; acute cerebrospinal meningitis; Adriamycin, cyclophosphamide, methotrexate; albumin- ...
APAP acetaminophen
IR APAP immediate release acetaminophen
EUROTOX European Committee on Chronic Toxicity Hazards
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AA Acetaminophen
AAP Acetaminophen
Acetaminophen Paracetamol
CTC Common Toxicity Criteria
DLT Dose limiting toxicity
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acetaminophen <drug> The generic name for a common nonprescription medication useful in the treatment of mild pain or fever. This is called paracetamol in the UK.
[American term]
Synonym: paracetamol.
(25 Jun 1999)
acetaminophen deacetylase <enzyme> Forms p-aminophenol
Registry number: EC 3.5.1.-
Synonym: apap deacetylase
(26 Jun 1999)
acute toxicity <pharmacology> Illness resulting from a single dose or exposure to a toxic substance.
Compare: chronic toxicity.
(06 May 1997)
chronic toxicity <pharmacology> Illness caused by repeated or long-term exposure to low doses of a toxic substance.
Compare: acute toxicity.
(09 Oct 1997)
digitalis toxicity A result of the over-accumulation of digitalis glycosides in the body. Kidney insufficiency can be a contributing factor.
Symptoms include nausea, vomiting, visual changes, blurred vision, anorexia and palpitations. Treatment is emergent as life-threatening cardiac arrhythmias are possible with higher blood levels.
(27 Sep 1997)
digoxin toxicity A result of the over-accumulation of digitalis glycosides in the body. Kidney insufficiency can be a contributing factor.
Symptoms include nausea, vomiting, visual changes, blurred vision, anorexia and palpitations. Treatment is emergent as life-threatening cardiac arrhythmias are possible with higher blood levels.
(27 Sep 1997)
drug toxicity The systemic effects of a drug that are related to the overall level of the medication in the bloodstream. Drug toxicity may occur with overdosage of a medication, accumulation of the drug in the body over time or the inability of the patients body to eliminate the drug.
(27 Sep 1997)
oxygen toxicity A body disturbance resulting from breathing high partial pressures of oxygen; characterised by visual and hearing abnormalities, unusual fatigue while breathing, muscular twitching, anxiety, confusion, incoordination, and convulsions; although the mechanism for development of the condition is obscure, a disruption of enzymatic activity is likely, perhaps as a result of free radical formation.
Synonym: oxygen poisoning.
(05 Mar 2000)
toxicity The quality of being poisonous, especially the degree of virulence of a toxic microbe or of a poison.
(18 Nov 1997)
toxicity test <investigation> Controlled laboratory test to determine the toxicity of a chemical to an organism in terms of specific chemical concentrations.
An acute toxicity test establishes the concentration required to kill a predetermined proportion of test organisms within a relatively short period of time, typically 4 days or less. A chronic toxicity test reveals the effects of a sublethal concentration applied throughout all or part of the life cycle.
(12 Jan 1998)
toxicity tests Tests that determine the toxicity of a substance. These include tests of clinical drugs, foods, environmental pollutants, etc.
(12 Dec 1998)
ep toxicity A test defined by the federal Environmental Protection Agency to check a substance for the presence of arsenic, barium, cadmium, chromium, lead, mercury, selenium, or silver. 40 CFR 261.24 defines the concentrations constituting hazardous waste and the test procedure.
(05 Dec 1998)
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