| LAK T cells | Lymphokine Activated Killer T cells |
|---|---|
| NK cell | Natural Killer cell |
| AAK | allo-activated killer |
| A-LAK | adherent lymphokine-activated killer [cell] |
| KAF | conglutinogen-activating factor; killer-assisting factor; kinase activating factor |
| NK | A-natural killer |
|---|---|
| AK | Activated killer |
| ALAK | Adherent lymphokine activated killer |
| CIK | Cytokine-induced killer |
| LAK | IL 2-activated killer |
| right whale | <zoology> The bowhead, Arctic, or Greenland whale (Balaena mysticetus), from whose mouth the best whalebone is obtained. Any other whale that produces valuable whalebone, as the Atlantic, or Biscay, right whale (Balaena cisarctica), and the Pacific right whale (B. Sieboldii); a bone whale. <zoology> Pygmy right whale, a small New Zealand whale (Neobalaena marginata) which is only about sixteen feet long. It produces short, but very elastic and tough, whalebone. Source: Websters Dictionary (01 Mar 1998) |
|---|---|
| whale | <zoology> Any aquatic mammal of the order Cetacea, especially any one of the large species, some of which become nearly one hundred feet long. Whales are hunted chiefly for their oil and baleen, or whalebone. The existing whales are divided into two groups: the toothed whales (Odontocete), including those that have teeth, as the cachalot, or sperm whale (see Sperm whale); and the baleen, or whalebone, whales (Mysticete), comprising those that are destitute of teeth, but have plates of baleen hanging from the upper jaw, as the right whales. The most important species of whalebone whales are the bowhead, or Greenland, whale, the Biscay whale, the Antarctic whale, the gray whale (see under Gray), the humpback, the finback, and the rorqual. Whale bird. A balanoglossus. Origin: OE. Whal, AS. Hwael; akin to D. Walvisch, G. Wal, walfisch, OHG. Wal, Icel. Hvalr, Dan. & Sw. Hval, hvalfisk. Cf. Narwhal, Walrus. Source: Websters Dictionary (01 Mar 1998) |
| whale fingers | An infection caused by erysipelothrix rhusiopathiae that is almost wholly restricted to persons who in their occupation handle infected fish, shellfish, poultry, or meat. Three forms of this condition exist: a mild localised form manifested by local swelling and redness of the skin; a diffuse form that might present with fever; and a rare systemic form associated with endocarditis. (12 Dec 1998) |
| sperm whale | <zoology> A very large toothed whale (Physeter macrocephalus), having a head of enormous size. The upper jaw is destitute of teeth. In the upper part of the head, above the skull, there is a large cavity, or case, filled with oil and spermaceti. This whale sometimes grows to the length of more than eighty feet. It is found in the warmer parts of all the oceans. Called also cachalot, and spermaceti whale. Pygmy sperm whale, a toothed cetacean (Hyperoodon bidens), found on both sides of the Atlantic and valued for its oil. The adult becomes about twenty-five feet long, and its head is very large and thick. Called also bottle-nosed whale. Source: Websters Dictionary (01 Mar 1998) |
| monocytes, activated killer | Monocytes made cytotoxic by ex vivo incubation with cytokines, especially interferon-gamma. Akm cells are used for adoptive immunotherapy in cancer patients. (12 Dec 1998) |
| natural killer cell | <haematology, immunology> A certain type of white blood cell that attacks tumour cells and infected body cells by binding to a tumour cell and releasing lethal chemicals. Natural killer cells are thought to play a key role in cancer prevention by killing abnormal cells before they multiply and grow. (16 Dec 1997) |
| natural killer cells | Large granular lymphocytes which do not express markers of either T or B-cell lineage. These cells do possess Fc receptors for IgG and can kill target cells using antibody-dependent cell-mediated cytotoxicity. NK cells can also use perforin to kill cells in the absence of antibody. Killing may occur without previous sensitization. Synonym: NK cells. (05 Mar 2000) |
| natural killer cell stimulating factor | <cytokine> A 75 kD heterodimeric cytokine composed of disulfide-bonded 40 kD and 35 kD subunits that was originally identified by its ability to induce cytotoxic effector cells in synergy with less than optimal concentrations of interleukin-2. It is released by macrophages in response to infection and promotes the activation of cell-mediated immunity. Specifically, IL-12 triggers the maturation of Thl CD4 cells, specific cytotoxic T-lymphocyte responses and an increase in the activity of NK cells and consequently, it is the initiator of cell-mediated immunity. It enhances the lytic activity of NK cells, induces interferon production, stimulates the proliferation of activated T-cells and NK cells. Is secreted by human B lymphoblastoid cells (NC 37). May play a role in controlling immunoglobulin isotype selection as it also inhibits IgE synthesis (even in the presence of anti-IFN monoclonal antibody) and as a growth factor for activated CD4+ and CD8+ T-cells independently of interleukin-2, and for CD56+ NK cells but not resting peripheral blood mononuclear cells or resting or activated tonsillar B-cells. It is likely that interleukin 12 has a major role in protective immunity against viruses and is under study as an immunotherapy in HIV infection. Formerly referred to as cytotoxic lymphocyte maturation factor. Acronym: IL-12 (12 Dec 1998) |
| nine-killer | <zoology> The northern butcher bird. Origin: So called because it is believed to kill and impale on thorns nine birds, etc, in succession. Source: Websters Dictionary (01 Mar 1998) |
| killer | 1. One who deprives of life; one who, or that which, kills. 2. <zoology> A voracious, toothed whale of the genus Orca, of which several species are known. The killers have a high dorsal fin, and powerful jaws armed with large, sharp teeth. They capture, and swallow entire, large numbers of seals, porpoises, and dolphins, and are celebrated for their savage, combined attacks upon the right whales, which they are said to mutilate and kill. The common Atlantic species (Orca gladiator), is found both on the European and the American coast. Two species (Orca ater and O. Rectipinna) occur on the Pacific coast. Source: Websters Dictionary (01 Mar 1998) |
| killer cell | 1. <immunology> Mammalian cells which can lyse antibody coated target cells. They have a receptor for the Fc portion of IgG and are probably of the mononuclear phagocyte lineage, though some may be lymphocytes. Not to be confused with cytotoxic T-cells which recognise targets by other means and are clearly a sub set of T lymphocytes. This confusion exists in the early literature. 2. Natural killer cell are CD3 negative large granular lymphocytes, mediating cytolytic reactions that do not require expression of Class I or II major histocompatibility antigens on the target cell. 3. Lymphokine activated killer cells are NK cells activated by interleukin-2 (LAK cells). (13 Nov 1997) |
| killer cells | Lymphocyte-like effector cells which mediate antibody-dependent cell cytotoxicity. They kill antibody-coated target cells which they bind with their fc receptors. (12 Dec 1998) |
| killer cells, lymphokine-activated | Cytolytic lymphocytes with the unique capacity of killing natural killer (nk)-resistant fresh tumour cells. They are interleukin-2-activated nk cells that have no MHC (major histocompatibility complex) restriction or need for antigen stimulation. Lak cells are used for adoptive immunotherapy in cancer patients. (12 Dec 1998) |
| killer cells, natural | Cells responsible for spontaneous cytotoxicity of a variety of tumour cells without prior immunization. These natural killer cells are found in non-immune humans and experimental animals and are thought by some to be the same as killer cells (killing by antibody-dependent cell cytotoxicity), but they can also kill in the absence of antibody. (12 Dec 1998) |
| killer plasmid | <molecular biology> These plasmids are found in some strains of Kluyveromyces marxianus where the cells contain multiple cytoplasmic copies of dsDNA plasmids. Such cells secrete a glycoprotein toxin. The plasmids and the killer function can be transferred to yeast. (18 Nov 1997) |
Synonyms : Orcinus orca, Killer Whales, Whales, Killer
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