| SCPNT | Southern California Postrotary Nystagmus Test |
|---|---|
| SCSIT | Southern California Sensory Integration Test |
| STSA | Southern Thoracic Surgical Association |
| SWOG | South West Oncology Group |
| WHYMPI | West Haven-Yale Multidimensional Pain Inventory |
| CARD | Catalysed Reporter Deposition |
|---|---|
| ENSO | El Nino Southern Oscillation |
| SB | Southern Blot |
| SBMV | Southern bean mosaic virus |
| SBH | Southern blot hybridisation |
| genes, reporter | Genes whose expression is easily detectable and therefore used to study promoter activity at many positions in a target genome. In recombinant DNA technology, these genes may be attached to a promoter region of interest. (12 Dec 1998) |
|---|---|
| reporter gene | <molecular biology> A gene that encodes an easily assayed product (e.g. CAT) that is coupled to the upstream sequence of another gene and transfected into cells. The reporter gene can then be used to see which factors activate response elements in the upstream region of the gene of interest. (18 Nov 1997) |
| africa, southern | The geographical area of africa comprising angola, botswana, lesotho, malawi, mozambique, namibia, south africa, swaziland, zambia, and zimbabwe. It includes what was formerly called south-west africa or german southwest africa but it was terminated in 1966 by a united nations resolution. (12 Dec 1998) |
| blot, southern | A common test for checking for a match between DNA molecules. DNA fragments are separated by agarose gel electrophoresis, transferred (blotted) onto membrane filters, and hybridised with complementary radiolabelled probes. The aim is to detect specific base sequenceswith the probes. Lest all of this sound esoteric, note that in the television series The X Files a Southern blot was done (in this case, to learn if some alien virus genome had been integrated into a person's genome). The Southern blot is named after its inventor, the British biologist M.E. Southern. There is also a Northern blot and a Western blot. (12 Dec 1998) |
| blotting, southern | A method (first developed by e.m. Southern) for detection of DNA that has been electrophoretically separated and immobilised by blotting on nitrocellulose or other type of paper or nylon membrane. (12 Dec 1998) |
| Southern | M.E., 20th century British biologist. See: Southern blot analysis. (05 Mar 2000) |
| southern blot | A technique used for searching for a specific DNA fragment. The process is as follows: 1. separate DNA fragments by gel electrophoresis 2. Change pH of gel to basic, thus allowing disruption of H-bonds 3. blot gel with nitrocellulose paper 4. Heat paper so as to fix DNA fragments 5. probe with labelled messenger RNA or cDNA 6. wash Complementary mRNA/cDNA fragments will have hybridised. (09 Oct 1997) |
| Southern blot analysis | A procedure to separate and identify DNA sequences; DNA fragments are separated by electrophoresis on an agarose gel, transferred (blotted) onto a nitrocellulose or nylon membrane, and hybridised with complementary (labelled) nucleic acid probes. (05 Mar 2000) |
| Southern blotting | <molecular biology, procedure> General term for the transfer of protein, RNA or DNA molecules from a relatively thick acrylamide or agarose gel or to a paper like membrane (usually nylon or nitrocellulose) by capilliarity or an electric field, preserving the spatial arrangment. Once on the membrane, the molecules are immobilised, typically by baking or by ultra violet irradiation and can then be detected at high sensitivity by hybridisation (in the case of DNA & RNA) or antibody labelling (in the case of protein). RNA blots are called Northern blots, DNA blots, Southern, protein blots, Western. (18 Nov 1997) |
| west | 1. The point in the heavens where the sun is seen to set at the equinox; or, the corresponding point on the earth; that one of the four cardinal points of the compass which is in a direction at right angles to that of north and south, and on the left hand of a person facing north; the point directly opposite to east. "And fresh from the west is the free wind's breath." (Bryant) 2. A country, or region of country, which, with regard to some other country or region, is situated in the direction toward the west. 3. Specifically: The Westen hemisphere, or the new World so called, it having been discovered by sailing westward from Europe; the Occident. Formerly, that part of the United States west of the Alleghany mountains; now, commonly, the whole region west of the Mississippi river; especially, that part which is north of the Indian Territory, new Mexico, etc. Usually with the definite article. West by north, West by south, according to the notation of the mariner's compass, that point which lies 11 1/4 deg to the north or south, respectively, of the point due west. West northwest, West southwest, that point which lies 22 1/2 deg to the north or south of west, or halfway between west and northwest or southwest, respectively. Origin: AS. West, adv.; akin to D. West, G. West, westen, OHG. Westan, Icel. Vestr, Sw. Vest, vester, vestan, Dan. Vest, vesten, and perhaps to L. Vesper evening, Gr. . Cf. Vesper, Visigoth. Source: Websters Dictionary (01 Mar 1998) |
| West African fever | A condition, now uncommon, resulting from Plasmodium falciparum infection (malignant tertian malaria with severe haemolysis); frequently seen in Caucasians after interrupted treatment with quinine. Synonym: blackwater fever, haemoglobinuric fever, West African fever. (05 Mar 2000) |
| West African sleeping sickness | A chronic disease of humans caused by Trypanosoma brucei gambiense in northern and sub-Saharan Africa from Senegal east to Sudan and Uganda; characterised by splenomegaly, drowsiness, an uncontrollable urge to sleep, and the development of psychotic changes; basal ganglia and cerebellar involvement commonly lead to chorea and athetosis; the terminal phase of the disease is characterised by wasting, anorexia, and emaciation that gradually leads to coma and death, usually from intercurrent infection. Synonym: chronic African sleeping sickness, chronic trypanosomiasis, West African sleeping sickness, West African trypanosomiasis. (05 Mar 2000) |
| West African trypanosomiasis | A chronic disease of humans caused by Trypanosoma brucei gambiense in northern and sub-Saharan Africa from Senegal east to Sudan and Uganda; characterised by splenomegaly, drowsiness, an uncontrollable urge to sleep, and the development of psychotic changes; basal ganglia and cerebellar involvement commonly lead to chorea and athetosis; the terminal phase of the disease is characterised by wasting, anorexia, and emaciation that gradually leads to coma and death, usually from intercurrent infection. Synonym: chronic African sleeping sickness, chronic trypanosomiasis, West African sleeping sickness, West African trypanosomiasis. (05 Mar 2000) |
| West, Charles | <person> English physician, 1816-1898. See: West's syndrome. (05 Mar 2000) |
| west indian | Belonging or relating to the West Indies. <botany> West India tea, a shrubby plant (Capraria biflora) having oblanceolate toothed leaves which are sometimes used in the West Indies as a substitute for tea. Source: Websters Dictionary (01 Mar 1998) |
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