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EGF-URO epidermal growth factor, urogastrone
UG geometric unsharpness; urogastrone; urogenital
URG urogastrone
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EGF-URO Epidermal growth factor-urogastrone
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urogastrone <endocrinology> A peptide isolated from human urine that inhibits gastric acid secretion. Now known to be identical to epithelial growth factor.
(18 Nov 1997)
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receptors, epidermal growth factor-urogastrone Glycoproteins of about 170 kD that have protein kinase activity and span the plasma membranes of growing cells, including tumours. They are activated by the binding of epidermal growth factor-urogastrone which then initiates DNA and protein synthesis. They are not found on mitotically quiescent cells except in the stomach where they control the synthesis and release of digestive enzymes and gastric acid. Transforming growth factor alpha also binds to and activates these receptors.
(12 Dec 1998)
epidermal growth factor-urogastrone <chemical> Single chain, nonhelical, acidic polypeptides of about 52 amino acids found in most mammals. Epidermal growth factor and urogastrone are not identical but seem to share biological acivities. They promote growth of, and cell proliferation in, certain tissues, especially epidermal structures and inhibit acid secretion by the stomach. They have been used to treat gastrointestinal ulcers.
Chemical name: Epidermal growth factor
(12 Dec 1998)
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A12700571 Urogastrone
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urogastrone human epidermal growth factor.
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