| ¿µ¹® | rheumatoid factor | ÇÑ±Û | ·ù¸¶Æ¼½º ÀÎÀÚ |
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| ¼³¸í | IgGÀÇ FcºÎÀ§¿¡ ÀÖ´Â Ç׿ø°áÁ¤ÀÎÀÚ¿¡ ´ëÇÑ Ç×ü·Î¼ ÀüÇüÀûÀÎ ¶Ç´Â È®½ÇÇÑ ·ù¸¶Æ¼½º°üÀý¿°(rheumatoid arthritis) ȯÀÚÀÇ 80%¿¡¼ ¹ß°ßµÈ´Ù. ·ù¸¶Æ¼½º ÀÎÀÚ´Â IgM, IgG, IgAÁß Çϳª°¡ µÉ ¼ö ÀÖÀ¸³ª ÁÖ·Î IgMÀÌ´Ù. ¼Ò¾Æ·ù¸¶Æ¼½º°üÀý¿°(juvenile rheumatoid arthritis: ¼Ò¾Æ±â¿¡ ¹ß»ýÇÏ´Â ·ù¸¶Æ¼½º°üÀý¿°)À» ºñ·ÔÇÑ, ´Ù¸¥ °áÇÕÁ¶Á÷º´À̳ª °¨¿°º´¿¡µµ ³ªÅ¸³¯ ¼ö ÀÖ´Ù |
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| ¿µ¹® | growth factor | ÇÑ±Û | ¼ºÀåÀÎÀÚ |
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| ¼³¸í | ¼¼Æ÷ÀÇ ºÐÈ ¹× ¼ºÀå¿¡ °ü¿©ÇÏ´Â ´Ü¹éÁú. ¼ºÀåÀÎÀÚ´Â Á¤»ó ¼¼Æ÷Áֱ⿡ ÇʼöÀûÀ̱⠶§¹®¿¡ µ¿¹°ÀÇ »ý¸í¿¡ Áß´ëÇÑ ¿ä¼Ò°¡ µÈ´Ù. ¹«¾ùº¸´Ùµµ ¼ºÀåÀÎÀڴ žÆÀÇ ¹ßÀ°À» Á¶Á¤Çϰí Á¶Á÷ÀÇ À¯Áö ¹× º¸¼ö¿¡ Áß´ëÇÑ ¿ªÇÒÀ» Çϸç, Ç÷±¸ÀÇ »ý¼ºÀ» ÀÚ±ØÇÑ´Ù. ¶ÇÇÑ ¾ÏÀÇ ÁøÇà°úÁ¤¿¡µµ °ü¿©ÇÑ´Ù. |
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| ¿µ¹® | risk factor | ÇÑ±Û | À§ÇèÀÎÀÚ |
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| ¼³¸í | ±¹Á¦¹æ»ç¼±¹æÈ£À§¿øÈ¸(ICRP)°¡ 1977³â ±Ç°í¿¡¼ ¹æ»ç¼±¹æÈ£ÀÇ ¸ñÀûÀ¸·Î äÅÃÇÑ Áö¼ö·Î, ´ÜÀ§¼±·®(1 Sv)´ç È®·üÀû ¿µÇâÀÇ ¹ß»ýÈ®·üÀ» ÃßÁ¤ÇÏ¿© ³ªÅ¸³½ °ÍÀÌ´Ù. »ý½Ä¼± ¼±·®¿¡ ´ëÇÑ À¯ÀüÀû¿µÇâÀÇ ¹ß»ý·ü(4¡¿10£3/Sv)À̳ª Àû»ö°ñ¼ö¼±·®¿¡ ´ëÇÑ ¹éÇ÷º´ ¹ß»ý·ü(2¡¿10£3/Sv)µî ¿Ü¿¡ »À, ÇãÆÄ, °©»ó»ù, Á¥»ù, ±âŸ Á¶Á÷ÀÇ À§ÇèÁö¼ö¸¦ ÃøÁ¤ÇÏ¿©, È®·üÀû ¿µÇâÀÇ Àü½Å¿¡ ÀÖ¾î¼ Ä¡»çÀ§ÇèÁö¼öÀÇ Çհ踦 16.5¡¿10£3/Sv·Î ÇÏ¿´´Ù. ±×ÈÄ ICRP´Â 1990³â ±Ç°í¿¡¼ ´ë»óÀÌ µÇ´Â Á¶Á÷°ú Àå±â¸¦ Ãß°¡Çϰí, ¼öÄ¡ °³Á¤À» ÇÏ¸é¼ ¸íεµ °¢¸ñÀûÈ®·üÁö¼ö¶ó°íÇÏ¿´´Ù. ÀÌ ±Ç°í¿¡ ÀÇÇϸé, Ä¡»çÀû È®·üÀû ¿µÇâÀÇ È®·üÁö¼öÀÇ ÇÕ°è´Â, ÀϹÝÀο¡ ÀÖ¾î 60.0¡¿10£3/SvÀÌ´Ù. |
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| ¿µ¹® | necrosis | ÇÑ±Û | ±«»ç |
|---|---|---|---|
| ¼³¸í | ¼¼Æ÷°¡ Á×´Â °ÍÀ» ¸»ÇÑ´Ù. ¿øÀÎÀº ¾î¶² ¿Ü»óÀÏ ¼öµµ ÀÖ°í, ȤÀº µ¿¸ÆÀÌ Á¼¾ÆÁ®¼ Çǰ¡ ÅëÇÏÁö ¾Ê¾Æ Á×°Ô µÇ´Â °ÍÀÏ ¼öµµ ÀÖ´Ù. ¾î¶² °æ¿ìÀ̵ç, ±«»çµÈ Á¶Á÷ÀÌ Ã¼³»¿¡ ÀÖÀ¸¸é, °á±¹Àº ¿©·¯ ÇÕº´ÁõÀ» ºÒ·¯ ÀÏÀ¸Å°¹Ç·Î Á¦°ÅµÇ¾î¾ß ÇÑ´Ù. ±«Àú±«»ç: gangrenous necrosis ±«Àú±«»ç¶ó´Â ¿ë¾î´Â º¸Åë ±«»ç¶ó´Â °Í°ú Å©°Ô ´Ù¸¥ °ÍÀº ¾øÀ¸³ª ÀÓ»ó, ƯÈ÷ ¿Ü°ú¿¡¼ ÈçÈ÷ ¾²°í ÀÖ´Â ¸»ÀÌ´Ù. ÀÌ´Â ÆÈ´Ù¸®, ƯÈ÷ ´Ù¸®¿¡¼ ¸¹ÀÌ »ý±â´Âµ¥ Ç÷¾×°ø±ÞÀÌ ¼Ò½ÇµÇ°í ±× ÈÄ¿¡ ¼¼±Õ°¨¿°À» ¹Þ¾Æ¼ »ý±â´Â º´ÅÍÀÌ´Ù. ¸¸¾à Ç÷·ù°ø±ÞÀÇ Â÷´Ü¿¡ ÀÇÇÑ Á¶Á÷ÀÇ Á×À½ÀÌ ÁÖº´º¯À̰í ÀÌÂ÷Àû ¼¼±ÕÀÇ °¨¿°ÀÌ Àû°í, ÀÖ´õ¶óµµ ¾ÆÁÖ ¹Ì¾àÇØ¼ º´ÅͰ¡ ¸¶¸£°í ¾×ü¼ººÐÀÌ ÀûÀ» °æ¿ì¿¡ À̰ÍÀ» °Ç¼º±«Àú(dry gangrene)À̶ó°í Çϰí, ¼¼±ÕÀÇ °¨¿°ÀÌ ¾ÆÁÖ ¸¹¾Æ¼ Á×Àº Á¶Á÷ÀÌ ºÐÇØ°¡ µÇ¾î¼ ¾×ü¼ººÐÀÌ ±«ÀúÀÇ Á¶Á÷¿¡ ¸¹ÀÌ ÀÖ¾î¼ º¸±â¿¡ ½ÀÇØ º¸À̸é À̰ÍÀ» ½À¼º±«Àú(wet gangrene)À̶ó°í ÇÑ´Ù. |
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| ¿µ¹® | fibrinoid necrosis | ÇÑ±Û | ¼¶À¯¼Ò¼º±«»ç |
|---|---|---|---|
| ¼³¸í | ÃʱâÀÇ ·ù¸¶Æ¼½º ȤÀº ¾Ç¼ºÁ¾¾ç µî¿¡¼ º¼ ¼ö ÀÖ´Â Ç÷°ü-°áÇÕÁ¶Á÷ÀÇ Æ¯À¯ÇÑ º¯È·Î Ç÷°üº®À̳ª ÁÖÀ§ÀÇ °áÇÕÁ¶Á÷ÀÌ ¼¶À¯¼Ò¸ð¾çÀ¸·Î ±ÕÁúÇÑ ¹°Áú·Î µÇ°í, È£»ê¼ºÀ¸·Î ¿°»öµÈ´Ù. À̰ÍÀº ¼¶À¯¼Ò¿Í °ÅÀÇ ¶È°°Àº ¿°»ö¼ºÀ» ³ªÅ¸³»±â ¶§¹®¿¡ ¿°Áõ¿¡¼ Ç÷°üÀ¸·ÎºÎÅÍ ¼¶À¯¼Ò ¶Ç´Â ¼¶À¯¼Ò¸ð¾çÀÇ ¹°ÁúÀÌ »ïÃâÇÏ¿© °áÇÕÁ¶Á÷ ¼¶À¯°£¿¡ Ä§ÂøÇÏ¿© ±¸Á¶°¡ ºÒ¸í·áÇÑ °ÍÀ¸·Î »ý°¢µÇ¾úÀ¸³ª, ÃÖ±Ù Á¶Á÷ÈÇÐ, ÀüÀÚÇö¹Ì°æ µî¿¡ ÀÇÇÏ¿© °áÇÕ¼¶À¯ÀÚü¿¡µµ º¯È°¡ ÀÖ´Â °ÍÀ¸·Î ¸é¿ª±Û·ÎºÒ¸°ÀÇ Ä§Âøµµ Áõ¸íµÇ°í ÀÖ´Ù. |
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| CF | calcaneal fibular [ligament]; calcium leucovorin; calf blood flow; calibration factor; cancer-free; ... |
|---|---|
| EF | ectopic focus; edema factor; ejection fraction; elastic fibril; electric field; elongation factor; e... |
| PF | pair feeding; peak flow; perfusion fluid; pericardial fluid; periosteal fibroblast; peritoneal fluid... |
| AChRs | Acetylcholine Receptors |
| RA | radioactive; ragocyte; ragweed antigen; rapidly adapting [receptors]; reactive arthritis; reciprocal... |
| TNF | Anti-tumor necrosis factor |
|---|---|
| anti-TNF alpha | Anti-tumor necrosis factor alpha |
| TNF | Cachectin/tumor necrosis factor |
| enTNF | Endogenous tumor necrosis factor |
| hTNF-alpha | Human Tumor Necrosis Factor-alpha |
IGF-II : insulin like growth factor-IIÀÇ ¾àÀÚ. ¸¹Àº Àå±â¿Í Á¶Á÷¿¡ ÀÛ¿ëÇÏ¿© ´Ü¹é ÇÕ¼º°ú DNA, RNAÀÇ ÇÕ¼ºÀ» Áõ°¡½ÃÄÑ ¼¼Æ÷ÀÇ ¼ö¿Í ¾çÀ» Áõ°¡
| tumor necrosis factor | <cytokine> Originally described as a tumour inhibiting factor in the blood of animals exposed to bacterial lipopolysaccharide or Bacille Calmette-Guerin. Preferentially kills tumour cells in vivo and in vitro, causes necrosis of certain transplanted tumours in mice and inhibits experimental metastases. Human Tumour Necrosis factor alpha is a protein of 157 amino acids and has a wide range of pro inflammatory actions. Usually considered a cytokine. Synonym: cachectin. Acronym: TNF (13 Nov 1997) |
|---|---|
| receptors, tumour necrosis factor | Cell surface receptors that bind tumour necrosis factor and trigger changes which influence the behaviour of cells. The two recognised tumour necrosis factor receptors are designated alpha and beta receptors. Both receptors bind both alpha and beta tumour necrosis factors with high affinity, and both are members of the nerve growth factor receptor family. (12 Dec 1998) |
| decoy | To lead into danger by artifice; to lure into a net or snare; to entrap; to insnare; to allure; to entice; as, to decoy troops into an ambush; to decoy ducks into a net. "Did to a lonely cot his steps decoy." (Thomson) "E'en while fashion's brightest arts decoy, The heart, distrusting, asks if this be joy." (Goldsmith) Synonym: To entice, tempt, allure, lure. See Allure. Origin: Pref. De- + coy; orig, to quiet, soothe, caress, entice. See Coy. Source: Websters Dictionary (01 Mar 1998) |
| decoy cells | Benign exfoliated epithelial cell's with pyknotic nuclei seen in urinary infections; may be mistaken for malignant cell's. (05 Mar 2000) |
| tumor | 1. <oncology> An abnormal mass of tissue that results from excessive cell division that is uncontrolled and progressive, also called a neoplasm. Tumours perform no useful body function. They may be either benign (not cancerous) or malignant. 2. Swelling, one of the cardinal signs of inflammations, morbid enlargement. Origin: L. Tumere = to swell (12 May 1997) |
| tumor marker | <investigation, oncology> A substance in the body that usually indicates the presence of cancer. These markers are usually specific to certain types of cancer and are usually found in the blood or other tissue samples. Examples are alphafetoprotein (AFP), human chorionic gonadotropin, and lactate dehydrogenase (LDH). They may be indicators of tumour stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids. (18 Jul 2002) |
| p60 tumour necrosis factor receptor-associated kinase | <enzyme> Interacts with and causes phosphorylation of the cytoplasmic domain of the tnf receptor Registry number: EC 2.7.10.- Synonym: p60 tnf receptor-associated kinase, p60-trak (26 Jun 1999) |
| tumour necrosis factor | <cytokine> Originally described as a tumour inhibiting factor in the blood of animals exposed to bacterial lipopolysaccharide or Bacille Calmette-Guerin. Preferentially kills tumour cells in vivo and in vitro, causes necrosis of certain transplanted tumours in mice and inhibits experimental metastases. Human Tumour Necrosis factor alpha is a protein of 157 amino acids and has a wide range of pro inflammatory actions. Usually considered a cytokine. Synonym: cachectin. Acronym: TNF (13 Nov 1997) |
| tumour necrosis factor-beta | <cytokine> A cytolytic factor that is produced by CD4 and CD8 T-cells after their exposure to an antigen. (05 Mar 2000) |
| receptors, atrial natriuretic factor | Cell surface proteins that bind atrial natriuretic factor with high affinity and trigger intracellular changes influencing the behaviour of cells. (12 Dec 1998) |
| receptors, colony-stimulating factor | Cell surface receptors for colony-stimulating factors, local mediators, and hormones that regulate the survival, proliferation, and differentiation of haemopoietic cells. (12 Dec 1998) |
| receptors, epidermal growth factor-urogastrone | Glycoproteins of about 170 kD that have protein kinase activity and span the plasma membranes of growing cells, including tumours. They are activated by the binding of epidermal growth factor-urogastrone which then initiates DNA and protein synthesis. They are not found on mitotically quiescent cells except in the stomach where they control the synthesis and release of digestive enzymes and gastric acid. Transforming growth factor alpha also binds to and activates these receptors. (12 Dec 1998) |
| receptors, fibroblast growth factor | Specific molecular sites or structures on cell membranes that react with fibroblast growth factors (both the basic and acidic forms), their analogs, or their antagonists to elicit or to inhibit the specific response of the cell to these factors. These receptors frequently possess tyrosine kinase activity. (12 Dec 1998) |
| receptors, granulocyte-colony-stimulating factor | Receptors that bind and internalise granulocyte-colony-stimulating factor. Their mw is believed to be 150 kD. These receptors are found mainly on a subset of myelomonocytic cells. (12 Dec 1998) |
| receptors, granulocyte-macrophage colony-stimulating factor | Receptors that bind and internalise the granulocyte-macrophage stimulating factor. Their mw is believed to be 84 kD. The most mature myelomonocytic cells, specifically human neutrophils, macrophages, and eosinophils, express the highest number of affinity receptors for this growth factor. (12 Dec 1998) |
Synonyms : Decoy Receptor for FAS Ligands, Decoy Receptor for TRAIL Ligands, Decoy Receptor, Tumor Necrosis Factor, Tumor Necrosis Factor Decoy Receptor, FAS Receptors, Decoy, Receptors, Decoy FAS, Receptors, Decoy TRAIL, TRAIL Receptors, Decoy
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