| TUB | tubulin |
|---|---|
| TUBA | tubulin alpha |
| TUBAL | tubulin alpha-like |
| TUBB | tubulin beta |
| TUBG | tubulin gamma |
| gaba modulators | Substances that do not act as agonists or antagonists but do affect the gaba receptor-ionophore complex. Gaba-a receptors (receptors, gaba-a) appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gaba-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. General anaesthetics probably act at least partly by potentiating gabaergic responses, but they are not included here. (12 Dec 1998) |
|---|---|
| alpha-tubulin acetylase | <enzyme> From chlamydomonas flagella; catalyses the acetylation of alpha-tubulin-l-lysine in the presence of acetyl-CoA to yield CoA and alpha-tubulin n(epsilon)-acetyl-l-lysine Registry number: EC 2.3.1.108 Synonym: alpha-tubulin acetyltransferase (26 Jun 1999) |
| tau-tubulin kinase | <enzyme> Mw 32 kD; phosphorylates tau, beta-tubulin, map2 and alpha-casein; novel and distinct fram tau protein kinase I and II Registry number: EC 2.7.10.- (26 Jun 1999) |
| tubulin | <cell biology, protein> Abundant cytoplasmic protein (55 kD), found mainly in two forms, _ and _. A tubulin heterodimer (one _, one _), constitutes the protomer for microtubule assembly. Multiple copies of tubulin genes are present (and are expressed) in most eukaryotic cells studied so far. The different tubulin isoforms seem, however, to be functionally equivalent. _ _ tubulin is localised in centrosome and is involved in nucleation of microtubule assembly during the cell cycle. Highly conserved from yeast to mammals. (18 Nov 1997) |
| tubulin-tyrosine ligase | <enzyme> An enzyme that covalently links a tyrosine to the C-terminal glutamyl residue of tubulin, coupled with the hydrolysis of ATP to ADP and Pi; this is a unique posttranslational modification that may have a significant role in cytoskeletal traffic and design. (05 Mar 2000) |
Synonyms : Microtubule Modulators, Tubulin Inhibitors, Tubulin Polymerization Inhibitors, Tubulin Polymerization Promoters, Tubulin Promoters, Inhibitors, Tubulin, Inhibitors, Tubulin Polymerization, Modulators, Microtubule, Modulators, Tubulin, Promoters, Tubulin
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