| ¿µ¹® | thrombin | ÇÑ±Û | Æ®·Òºó |
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| CR | calculation rate; calculus removed; calorie-restricted; cardiac rehabilitation; cardiac resuscitatio... |
|---|---|
| TOP | termination of pregnancy; topoisomerase |
| top | topical |
| TT | 1) Thrombin Time 2) Transient Thyrotoxicosis |
| HT | Hashimoto thyroiditis; hearing test; hearing threshold; heart; heart transplantation, heart transpla... |
| BBTV | Banana bunchy top virus |
|---|---|
| BCTV | Beet curly top virus |
| TOP | termination of pregnancy |
| AT III | Anti-thrombin III |
| THR | Thrombin |
| receptors, thrombin | Cell surface proteins that specifically bind thrombin and trigger changes in the behaviour of blood cells. There are at least two types of thrombin receptors on platelets. The higher affinity receptors mediate the inhibition of stimulated adenylate cyclase, the secretion of acid hydrolases, and the activation of phospholipase a2. The lower affinity receptors are linked to phospholipase c and trigger platelet aggregation and exposure of fibrinogen binding sites. A human platelet thrombin receptor has been cloned and is a member of the family of peptide receptors. There are also thrombin receptors on endothelial cells and smooth muscle cells. (12 Dec 1998) |
|---|---|
| human thrombin | Thrombin obtained from human plasma by precipitation with suitable salts and organic solvents; same uses as thrombin. (05 Mar 2000) |
| thrombin | <enzyme> Protease (34 kD) generated in blood clotting that acts on fibrinogen to produce fibrin. Consists of two chains, A and B, linked by a disulphide bond. B chain has sequence homology with pancreatic serine proteases: cleaves at Arg Gly. Thrombin is produced from prothrombin by the action either of the extrinsic system (tissue factor + phospholipid) or, more importantly, the intrinsic system (contact of blood with a foreign surface or connective tissue). Both extrinsic and intrinsic systems activate plasma factor X to form factor Xa which then, in conjunction with phospholipid (tissue derived or platelet factor 3) and factor V, catalyses the conversion. (18 Nov 1997) |
| thrombin time | Test of the conversion of fibrinogen to fibrin by thrombin in which clotting time of plasma mixed with a thrombin solution is measured. Time is prolonged by afibrinogenaemia, abnormal fibrinogen, or the presence of inhibitory substances, e.g., fibrin-fibrinogen degradation products, heparin. Reptilase, a thrombin-like enzyme unaffected by the presence of heparin, may be used in place of thrombin. (12 Dec 1998) |
| top | 1. To cover on the top; to tip; to cap; chiefly used in the past participle. "Like moving mountains topped with snow." (Waller) "A mount Of alabaster, topped with golden spires." (Milton) 2. To rise above; to excel; to outgo; to surpass. "Topping all others in boasting." (Shak) "Edmund the base shall top the legitimate." (Shak) 3. To rise to the top of; to go over the top of. "But wind about till thou hast topped the hill." (Denham) 4. To take off the or upper part of; to crop. "Top your rose trees a little with your knife." (Evelyn) 5. To perform eminently, or better than before. "From endeavoring universally to top their parts, they will go universally beyond them." (Jeffrey) 6. To raise one end of, as a yard, so that that end becomes higher than the other. To top off, to complete by putting on, or finishing, the top or uppermost part of; as, to top off a stack of hay; hence, to complete; to finish; to adorn. 1. A child's toy, commonly in the form of a conoid or pear, made to spin on its point, usually by drawing off a string wound round its surface or stem, the motion being sometimes continued by means of a whip. 2. A plug, or conical block of wood, with longitudital grooves on its surface, in which the strands of the rope slide in the process of twisting. Origin: CF. OD. Dop, top, OHG, MNG, & dial. G. Topf; perhaps akin to G. Topf a pot. 1. The highest part of anything; the upper end, edge, or extremity; the upper side or surface; summit; apex; vertex; cover; lid; as, the top of a spire; the top of a house; the top of a mountain; the top of the ground. "The star that bids the shepherd fold, Now the top of heaven doth hold." (Milton) 2. The utmost degree; the acme; the summit. "The top of my ambition is to contribute to that work." (Pope) 3. The highest rank; the most honorable position; the utmost attainable place; as, to be at the top of one's class, or at the top of the school. "And wears upon hisbaby brow the round And top of sovereignty." (Shak) 4. The chief person; the most prominent one. "Other . . . Aspired to be the top of zealots." (Milton) 5. The crown of the head, or the hair upon it; the head. "From top to toe" "All the stored vengeance of Heaven fall On her ungrateful top !" (Shak) 6. The head, or upper part, of a plant. "The buds . . . Are called heads, or tops, as cabbageheads." (I. Watts) 7. A platform surrounding the head of the lower mast and projecting on all sudes. It serves to spead the topmast rigging, thus strengheningthe mast, and also furnishes a convenient standing place for the men aloft. 8. A bundle or ball of slivers of comkbed wool, from which the noils, or dust, have been taken out. 9. Eve; verge; point. "He was upon the top of his marriage with Magdaleine." 10. The part of a cut gem between the girdle, or circumference, and the table, or flat upper surface. Top is often used adjectively or as the first part of compound words, usually self-explaining; as, top stone, or topstone; top-boots, or top boots; top soil, or top-soil. Top and but, a phrase used to denote a method of working long tapering planks by bringing the but of one plank to the top of the other to make up a constant breadth in two layers. <zoology> Top minnow, a small viviparous fresh water fish (Gambusia patruelis) abundant in the Southern United States. Also applied to other similar species. Origin: AS. Top; akin to OFries. Top a tuft, D. Top top, OHG. Zopf end, tip, tuft of hair, G. Zopf tuft of hair, pigtail, top of a tree, Icel. Toppr a tuft of hair, crest, top, Dan. Top, Sw. Topp pinnacle, top; of uncertain origin. Cf. Tuft. Source: Websters Dictionary (01 Mar 1998) |
| top-shaped | <botany> Having the shape of a top; cone-shaped, with the apex downward; turbinate. Source: Websters Dictionary (01 Mar 1998) |
| top-shell | <zoology> Any one of numerous species of marine top_shaped shells of the genus Thochus, or family Trochidae. Source: Websters Dictionary (01 Mar 1998) |
| turban-top | <botany> A kind of fungus with an irregularly wrinkled, somewhat globular pileus (Helvella, or Gyromitra, esculenta). Source: Websters Dictionary (01 Mar 1998) |
| flat top waves | Activity in the electroencephalogram having a pattern suggesting a flat top; these wave's are often found in temporal lobe discharges. (05 Mar 2000) |
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