| ¿µ¹® | protein | ÇÑ±Û | ´Ü¹éÁú |
|---|---|---|---|
| ¼³¸í | ź¼Ò, ¼ö¼Ò, »ê¼Ò, Áú¼Ò, ȲÀ» ÇÔÀ¯Çϰí ÀÖ´Â À¯±âÈÇÕ¹°·Î, ¸ðµç ¼¼Æ÷ÀÇ ¿øÇüÁúÀ» ÀÌ·ç°í ÀÖ´Â ±âº» ±¸¼º¹°ÁúÀÌ´Ù. ´Ü¹éÁúÀº ±× ´ÜÀ§ÀÎ ¾Æ¹Ì³ë»êµéÀÌ ÆéƼµå°áÇÕ¿¡ ÀÇÇØ °áÇյǾî ÀÖÀ¸¸ç, º¸Åë 20°³ÀÇ ¾Æ¹Ì³ë»êµéÀÌ ´Ù¸¥ ¼ø¼¿Í Á¶¼ºÀ» °¡Áö°í ¹è¿µÇ¾î, µ¶Æ¯ÇÑ ÇϳªÀÇ ´Ü¹éÁúÀ» Çü¼ºÇÏ°Ô µÈ´Ù. |
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| ¿µ¹® | brain death | ÇÑ±Û | ³ú»ç |
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| ¼³¸í | ³ú±â´ÉÀÌ ¿ÏÀüÈ÷ Á¤ÁöµÇ¾î ȸº¹ ºÒ´ÉÇÑ »óÅÂ. ³úÀÇ ±â´É¿¡´Â ´ë³ú¹Ý±¸ÀÇ ±â´É À̿ܿ¡ ³ú°£ÀÇ ±â´Éµµ Æ÷ÇԵȴÙ. ³ú»ç´Â Àΰ£ÀÇ Á×À½°ú °°Àº ¶æÀÌ ¾Æ´Ï°í, º¸ÅëÀº ³ú»ç ´ÙÀ½¿¡ Á×À½ÀÌ ¿Â´Ù. ½ÉÀåÀÌ½Ä ¼ö¼ú¿¡´Â °¡´ÉÇÑ ÇÑ ½Å¼±ÇÑ ½ÉÀåÀÌ ÇÊ¿äÇϱ⠶§¹®¿¡ ½ÉÀå Á¦°øÀÚÀÇ Á×À½À» ³ú»ç·Î ±ÔÁ¤ÇÏ·Á´Â ¿òÁ÷ÀÓÀÌ ÀÖ¾ú´Ù. 1968³â 8¿ù ¼¼°èÀÇ»çȸ ÃÑȸ¿¡¼ äÅÃµÈ Àå±âÀ̽Ŀ¡ °üÇÑ ¼±¾ð(½Ãµå´Ï ¼±¾ð)¿¡¼´Â ¨ç ½ÉÀå Á¦°øÀÚÀÇ Á×À½ÀÇ ÆÇÁ¤Àº ³úÆÄÃøÁ¤»óÀÇ ³úÆÄÀÇ Á¤Áö(³ú»ç)·Î °áÁ¤ÇØ¾ß ÇÑ´Ù. ¨è Á¦°øÀÚÀÇ Á×À½À» È®ÀÎÇϴµ¥ µÎ¸íÀÌ»óÀÇ Àǻ簡 ÀÔÈ¸ÇØ¾ß Çϸç, ³ú»çÀÇ °áÁ¤¿¡ Âü¿©ÇÑ ÀÇ»ç´Â À̽ļö¼ú¿¡ °ü¿©Çؼ´Â ¾È µÈ´Ù°í Çß´Ù. ±×·¯³ª ³úÆÄÃøÁ¤¸¸À¸·Î´Â ³úÁÙ±âÀÇ ±â´ÉÁ¤Áö¸¦ ÆÇÁ¤ÇÒ ¼ö ¾ø°í, ³ú»çÀÇ ÆÇÁ¤µµ Áúº´ÀÇ Á¾·ù³ª Áøµµ¿¡ µû¶ó ±âÁØÀÌ ´Þ¶óÁö¹Ç·Î ÆÇÁ¤±âÁØÀÇ °ËÅä°¡ ÇÊ¿äÇÏ´Ù. ³úÁ¾¾ç-³ú¿Ü»ó-Ç÷ÇàÀå¾Ö µî ³úÁúȯÀÇ Áõ·Ê¿¡¼ º¸¸é ¨ç ±íÀº È¥¼ö, ¨è ¾çÂÊ µ¿°øÀÇ È®´ë ¹× µ¿°øÀÇ ºû¹Ý»ç¿Í °¢¸·¹Ý»çÀÇ ¼Ò½Ç, ¨é È£ÈíÀÇ Á¤Áö, ¨ê ³úÆÄÀÇ ÆòźÈ, ¨ë Ç÷¾ÐÀÇ ±Þ°ÝÇÑ ÀúÇÏ¿Í ±×¿¡ µû¸¥ ÀúÇ÷¾Ð µî ´Ù¼¸ °¡Áö Á¶°ÇÀÌ 6½Ã°£ ÈÄ¿¡µµ µ¿ÀÏÇÑ »óÅ¿¡ ÀÖ´Â °Í µî ¿©¼¸°¡Áö Á¶°ÇÀÌ ÆÇÁ¤ ±âÁØÀÌ µÇ¾ú¾ú´Ù. ÇöÀç´Â °¡Àå °·ÂÇÑ µ¿ÅëÀڱؿ¡ ´ëÇØ¼µµ ÀüÇô ¾Æ¹«·± °¨¼ö¼º°ú ¹ÝÀÀ¼ºÀ» ³ªÅ¸³»Áö ¾Ê´Â 24½Ã°£¿¡ °ÉÄ£ È¥¼ö·Î¼, Àڹ߿ ¶Ç´Â ÀÚ¹ßÈ£ÈíÀÌ ¾ø°í À¯¹ß¹Ý»ç°¡ ¼Ò½ÇµÇ°í ³úÀÇ Àü±âȰµ¿ÀÌ ¾ø¾îÁö´Â ȸº¹ºÒ°¡´ÉÇÑ ÀǽļҽÇÀ̶ó°í Á¤ÀÇÇϰí ÀÖ´Ù. |
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| ¿µ¹® | death | ÇÑ±Û | »ç¸Á, Á×À½, »ç |
|---|---|---|---|
| ¼³¸í | 1. »ý¸íȰµ¿ÀÌ Á¤ÁöµÇ¾î ´Ù½Ã ¿ø»óÅ·Πµ¹¾Æ¿ÀÁö ¾Ê´Â »ý¹°ÀÇ »óÅÂ. »îÀÇ Á¾¸»À» ¸»ÇÑ´Ù. ¿¹¸¦ µé¾î ¾Æ¸Þ¹Ù µîÀÇ ´Ü¼¼Æ÷ »ý¹°¿¡¼´Â 2°³Ã¼·Î ºÐ¿µÉ ¶§°¡ Á×À½À̶ó°í ¸»ÇÒ ¼ö ÀÖÀ»Áö ¸ð¸£³ª ´Ù¼¼Æ÷ »ý¹°¿¡ À־ ¼¼Æ÷ºÐ¿Àº ´Ü¼øÇÑ ¼ºÀåÀÇ ÇÑ °úÁ¤ÀÌ´Ù. »ý¹°Àº »ý½Ä¼¼Æ÷¸¦ ¸Å°³·Î »ý¸íÀ» ¿µ¿øÈ÷ Á¸¼Ó½ÃŰ´Â °ÍÀ̶ó°í º¼ ¼ö ÀÖ´Ù. Àΰ£À» Æ÷ÇÔÇÑ °íµîµ¿¹°¿¡ ÇÑÁ¤ÇÑ´Ù°í Çϸé Á×À½À̶õ ±× °³Ã¼¸¦ ±¸¼ºÇÏ´Â ¸ðµç Á¶Á÷ ¼¼Æ÷ÀÇ »ýȰ±â´ÉÀÇ Á¤Áö¶ó°í ¸»ÇÒ ¼ö ÀÖ´Ù. µû¶ó¼, ±¹ºÎÀûÀÎ ÇÑ ºÎºÐÀÇ »ýȰ±â´ÉÀÇ Á¤Áö¸¸À¸·Î´Â Á×À½À̶ó°í ÇÒ ¼ö ¾ø´Ù. 2. »ç¶÷ÀÌ Á×À½. »ç¶÷ÀÇ Á×À½Àº ³× °³ÀÇ Ãø¸éÀÌ ÀÖ´Ù. Áï ¨ç À°Ã¼Àû Á×À½(biological death), ¨è ½É¸®Àû Á×À½(psychological death), ¨é »çȸÀû Á×À½(social death), ¨ê ¹®ÈÀû Á×À½(culture death)À¸·Î »ý°¢ÇÒ ¼ö ÀÖ´Ù. Àΰ£ÀÇ ÀÏ»ýÀº ´ÜÁö »ý¸íÀÇ ¿¬Àå »Ó ¾Æ´Ï¶ó ÁúÀû Ãø¸é¿¡¼ ½É¸®Àû, »çȸÀû, ¹®ÈÀûÀÎ Ãæ½ÇÇÔÀÌ ÇÊ¿äÇÏ´Ù. ±Ù³â¿¡ ÀÇ·á±â¼úÀÇ ´«ºÎ½Å ¹ß´Þ¿¡ µû¶ó¼ ´õ¿í »ýȰÀÇ ÁúÀÌ Áß¿ä½ÃµÇ°í ÀÖ´Ù. ÀϹÝÀûÀ¸·Î À°Ã¼ÀûÀÎ Á×À½ÀÇ Á¤ÀÇ´Â ¸ðµç »ýü±â´ÉÀÇ ¿µ±¸Àû Á¤Áö. Áï ¨ç Àüü³ú±â´É, ¨è È£Èí°èÀÇ Àڹ߱â´É, ¨é ¼øÈ¯°èÀÇ Àڹ߱â´É, ÀÌ ¸ðµç °ÍÀÇ ºñ°¡¿ªÀûÀ¸·Î Á¤ÁöµÇ¾úÀ½À» ¸»ÇÑ´Ù. |
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| ¿µ¹® | sudden infant death syndrome | ÇÑ±Û | ¿µ¾Æ±Þ»çÁõÈıº |
|---|---|---|---|
| ¼³¸í | ÇÑ »ì ÀÌÇÏÀÇ °Ç°ÇÑ ¾Æ±â°¡ ¾Æ¹«·± Á¶ÁüÀ̳ª ¿øÀÎ ¾øÀÌ °©Àڱ⠻ç¸ÁÇßÀ» °æ¿ì¿¡ ³»¸®´Â Áø´ÜÀÌ´Ù. ÀÌ ÁõÈıºÀº »ýÈÄ 1~4°³¿ù »çÀÌ¿¡ °¡Àå ¸¹ÀÌ ¹ß»ýÇϸç, ´ëºÎºÐ ¹ã 10½Ã¿¡¼ ¿ÀÀü 10½Ã »çÀÌ¿¡ ¹ß»ýÇÑ´Ù. Á¶»êÇϰųª ºÎ¸ð°¡ Èí¿¬ÀÚÀÏ °æ¿ì, 20¼¼ ÀÌÇÏ »ê¸ðÀÇ ÃÊ»ê, ÀÓ½ÅÀü °Ç°°ü¸®¿¡ ¼ÒȦÇÑ »ê¸ð¿¡°Ô¼ ÅÂ¾î³ ¿µ¾Æ¿¡°Ô¼ ¸¹ÀÌ ¹ß»ýÇÑ´Ù. ÀÌ ÁõÈıºÀ¸·Î »ç¸ÁÇÑ ¿µ¾ÆÀÇ ÇüÁ¦ÀÏ °æ¿ì ÀϹÝÀûÀÎ ¿µ¾Æº¸´Ù °É¸± È®·üÀÌ ³ôÀº °ÍÀ¸·Î ¾Ë·ÁÁ® ÀÖ´Ù. |
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| TNF | Tumor Necrosis Factor; Á¾¾ç ±«»ç ÀÎÀÚ |
|---|---|
| rH-TNF | recombinant human tumor necrosis factor |
| TNF | true negative fraction; tumor necrosis factor |
| SIDS | Sudden Infant Death Syndrome; ¿µ¾Æ µ¹¿¬»ç ÁõÈıº = Crib Death |
| BD | barbital-dependent; barbiturate dependence; base deficit; base of prism down; basophilic degeneratio... |
| TNF-BP | TNF binding protein |
|---|---|
| FADD | FAS-associated death domain protein |
| r-TNF-alpha | Recombinant TNF-alpha |
| TNF-R | TNF-alpha receptor |
| DED | death effector domain |
| TNF-IL1-activated protein kinase | <enzyme> Phosphorylates beta casein in vitro; not the same as casein kinase 1 and casein kinase 2; not activated by mitogens, celllular stresses or any other cytokines than il1 and tnf Registry number: EC 2.7.1.- Synonym: tip kinase, beta casein kinase (26 Jun 1999) |
|---|---|
| TNF | <cytokine> Originally described as a tumour inhibiting factor in the blood of animals exposed to bacterial lipopolysaccharide or Bacille Calmette-Guerin. Preferentially kills tumour cells in vivo and in vitro, causes necrosis of certain transplanted tumours in mice and inhibits experimental metastases. Human Tumour Necrosis factor alpha is a protein of 157 amino acids and has a wide range of pro inflammatory actions. Usually considered a cytokine. Synonym: cachectin. Acronym: TNF (13 Nov 1997) |
| apple domain | <molecular biology> A consensus sequence, composed of 90 amino acids including 6 cysteines, that forms a characteristic, vaguely apple shaped, pattern via disulphide bridges. Shared by plasma kallikrein and coagulation factor XI, both serine proteases. (18 Nov 1997) |
| carboxy-terminal domain kinase | <enzyme> Protein kinase that phosphorylates the c-terminal repeat domain of the largest subunit of RNA polymerase II at serine residues Registry number: EC 2.7.1.- Synonym: ctd kinase, hs-ctd kinase, tfiih-associated ctd kinase (26 Jun 1999) |
| paired box domain | <molecular biology> Conserved domain of 128 amino acids, found in several developmentally regulated proteins in Drosophila (for example paired, gooseberry, Pox), mouse and human (for example Pax, HuP1, HuP48). (18 Nov 1997) |
| POU domain | <molecular biology> A conserved protein domain of around 150 amino acids, composed of a 20 amino acid homeobox domain and a larger POU specific domain and so is the target of some transcription factors. Named POU (Pit Oct Unc) after 3 such proteins: Pit 1 regulates expression of certain pituitary genes, Oct 1 and 2, that bind an octamer sequence in the promoters of histone H2A and some immunoglobulin genes and Unc 86, involved in nematode sensory neuron development. (31 Dec 1997) |
| SH3 domain-containing proline-rich kinase | <enzyme> A protein kinase which both phosphorylates ser and thr residues and has an sh3 domain; contains 847 amino acid residues; mol mass 92,688 da; genbank u07747 Registry number: EC 2.7.10.- Synonym: src-homology 3 domain-containing proline-rich kinase, sprk protein, sprk gene product (26 Jun 1999) |
| dinucleotide domain | A structural domain in certain proteins that binds NAD+ or NADP+. Synonym: dinucleotide domain. (05 Mar 2000) |
| domain | <molecular biology> Used to describe a part of a molecule or structure that shares common physico chemical features, for example hydrophobic, polar, globular, helical domains or properties for example DNA binding domain, ATP binding domain. (18 Nov 1997) |
| EGF like domain | Region of 30-40 amino acids containing 6 cysteines found originally in EGF and also in a range of proteins involved in cell signalling. Examples: TGF _, amphiregulin, urokinase, tissue plasminogen activator, complement C6 C9, fibronectin, laminin (each subunit at least 13 times), nidogen, selectins. It is also found in the Drosophila gene products: Notch (36 times) Delta, Slit, Crumbs, Serrate. (18 Nov 1997) |
| exit domain | <molecular biology> One of the two main binding sites on the ribosome molecule. The finished portion of the polypeptide being translated is attached to this site and leaves the ribosome from this site when the entire polypeptide is finished. (09 Oct 1997) |
| frequency domain | The expression of a function by its amplitude and phase at each component frequency, usually as determined by Fourier analysis. (05 Mar 2000) |
| LIM domain | Domain found in proteins required for developmental decisions. Contain 60 residue conserved, cysteine rich, repeats. Named after first 3 genes in group: Lin 11 (C. Elegans required for asymmetric division of blast cells), IsI 1 (mammalian insulin gene binding enhancer protein), mec 3 (C. Elegans required for differentiation of a set of sensory neurons). (18 Nov 1997) |
| attitude to death | Conceptual response of the individual to the various aspects of death, which are based on his psychosocial and cultural experience. (12 Dec 1998) |
| Black Death | <disease, organism> Yersinina pestis is a gram-negative, rod-shaped, faculatively anaerobic bacterial species in the family Enterobacteriaceae. It causes bubonic plaque, which is transmitted by rodent fleas. Historically known as the Black Plague, this disease devastated Europe and Asia in the 1300s. It still exists today and is characterised by sudden high fever, chills, excessively swollen and tender lymph nodes (buboes), followed by tissue bleeding and gangrene. Other complications include pneumonia and septicaemia. (12 Nov 1997) |
Synonyms : TRADD Protein, TNF Receptor Associated Death Domain Protein
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