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T-lymphocytes Lymphoid cells concerned with cell-mediated immunity. They originate from lymphoid stem cells that migrate from the bone marrow to the thymus and differentiate under the influence of the thymic hormones. Various subpopulations have been described.
(12 Dec 1998)
T-lymphocytes, cytotoxic Immunised T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (mlc), in vivo during a graft-versus-host (gvh) reaction, or after immunization with an allograft, tumour cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (cml). These cells are distinct from natural killer cells (killer cells, natural) and from killer cells mediating antibody-dependent cell cytotoxicity.
(12 Dec 1998)
T-lymphocytes, helper-inducer Subpopulation of CD4+ lymphocytes that cooperate with other lymphocytes (either t or b) to initiate a variety of immune functions. For example, helper-inducer T-cells cooperate with B-cells to produce antibodies to thymus-dependent antigens and with other subpopulations of T-cells to initiate a variety of cell-mediated immune functions.
(12 Dec 1998)
T-lymphocytes, suppressor-effector Subpopulation of CD8+ T-lymphocytes which suppress antibody production or inhibit cellular immune responses. Suppressor-effector cells execute the message received from suppressor-inducer cells (T-lymphocytes, suppressor-inducer).
(12 Dec 1998)
T-lymphocytes, suppressor-inducer Subpopulation of CD4+ lymphocytes which induce CD8+ suppressor T-cells (T-lymphocytes, suppressor-effector) to suppress antibody production by B-cells. They also stimulate other cellular immune responses.
(12 Dec 1998)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 4 ÆäÀÌÁö: 1
  • T-Lymphocytes - »õâ Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.
    Synonyms : Lymphocyte, Thymus-Dependent, Lymphocytes, Thymus-Dependent, T Cells, T Lymphocytes, T-Cell, T-Lymphocyte, Thymus Dependent Lymphocytes, Thymus-Dependent Lymphocyte
  • T-Lymphocytes, Cytotoxic - »õâ Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (CML). These CD8-positive cells are distinct from natural killer cells (KILLER CELLS, NATURAL) and from KILLER CELLS mediating antibody-dependent cell cytotoxicity. There are two effector phenotypes: TC1 and TC2.
    Synonyms : Cell Mediated Lympholytic Cells, Cell, Cell-Mediated Lympholytic, Cell, TC1, Cell, TC2, Cell-Mediated Lympholytic Cell, Cells, Cell-Mediated Lympholytic, Cells, TC1, Cells, TC2, Cytotoxic T Lymphocytes, Cytotoxic T-Lymphocyte, Lympholytic Cell, Cell-Mediated
  • T-Lymphocytes, Helper-Inducer - »õâ Subpopulation of CD4+ lymphocytes that cooperate with other lymphocytes (either T or B) to initiate a variety of immune functions. For example, helper-inducer T-cells cooperate with B-cells to produce antibodies to thymus-dependent antigens and with other subpopulations of T-cells to initiate a variety of cell-mediated immune functions.
    Synonyms : Helper T-Cells, Helper Cell, Helper Inducer T Lymphocytes, Helper T Cells, Helper T-Cell, Helper T-Lymphocyte, Helper T-Lymphocytes, Helper-Inducer T-Cell, Helper-Inducer T-Cells, Helper-Inducer T-Lymphocyte, Inducer Cell, Inducer T-Lymphocyte, T-Cell, Helper
  • T-Lymphocytes, Regulatory - »õâ CD4-positive T cells that inhibit immunopathology or autoimmune disease in vivo. These include naturally occurring CD4+CD25+ Treg cells, IL-10 secreting Tr1 cells, and Th3 cells.
    Synonyms : Regulatory T-Cells, Tr1 Cells, Treg Cells, Cell, Th3, Cell, Tr1, Cell, Treg, Cells, Th3, Cells, Tr1, Cells, Treg, Regulatory T Cells, Regulatory T Lymphocytes, Regulatory T-Lymphocyte, Suppressor Cell, T Cells, Regulatory, T Lymphocytes, Regulatory, Th3 Cell, Tr1 Cell
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