| sincalide | <chemical> 1-de(5-oxo-l-proline)-2-de-l-glutamine-5-l-methioninecaerulein. The eight-amino-acid carbon-terminal fragment and physiologically active portion of the cholecystokinin-pancreozymin molecule. It stimulates the GI tract, especially gallbladder and pancreas, and has many, often depressant, effects on the CNS. It is also a neurotransmitter. It is used to diagnose gallbladder disease and has also been proposed as an anorexic. Its amino acid sequence is: l-asp-(o-sulfo)-l-tyr-l-met-l-gly-l-trp-l-met-l-alpha-asp-l-phe-amide. Chemical name: Caerulein, 1-de(5-oxo-L-proline)-2-de-L-glutamine-5-L-methionine- (12 Dec 1998) |
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Synonyms : Bracco Brand of Sincalide, CCK-OP, Cholecystokinin Pancreozymin C-Terminal Octapeptide, H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2, Kinevac, OP-CCK, SQ-19, 844, SQ-19844, Syncalide, Cholecystokinin Pancreozymin C Terminal Octapeptide, SQ 19, 844, SQ 19844, SQ19, 844
| sincalide |
[USP] the synthetic C-terminal octapeptide of cholecystokinin, used to stimulate gallbladder contraction in gallbladder function testing and cholecystography; administered intravenously.
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