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  • SCID= Severe combined mmunodeficiency
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  • transgenic mice
  • scid(severe combined immunodeficiency disease)
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  • scid= severe combined mmunodeficiency
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  • Jimpy mice
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  • nude mice
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SCID Severe Combined Immuno-Deficiency; ÁßÁõ º¹ÇÕ ¸é¿ª °áÇÌÁõ
SCID severe combined immunodeficiency [syndrome]; soft copy image display; Structured Clinical Interview ...
EDIM epizootic diarrhea of infant mice
MVM microvillose membrane; minute virus of mice
PFC pair-fed control [mice]; patient-focused care; pelvic flexion contracture; perfluorocarbon; pericard...
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scid mice severe combined immune deficiency
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SCID scid-/scid
MVM Minute Virus of Mice
MVMp Minute Virus of Mice
PVM Pneumonia virus of mice
SAM Senescence Accelerated Mice
CancerWEB ¿µ¿µ ÀÇÇлçÀü ¸ÂÃã °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
SCID mice <abbreviation> Severe combined immunodeficient mice.
(05 Mar 2000)
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mice, scid Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of b- and T-cell immunity resembles severe combined immunodeficiency (scid) syndrome in human infants. Scid mice are useful as animal models since they are receptive to implantation of a human immune system producing scid-human (scid-hu) haematochimeric mice.
(12 Dec 1998)
SCID <abbreviation> Severe combined immunodeficiency.
(05 Mar 2000)
biozzi mice <immunology> Any genetic line of mice which has been bred to have unusually high or unusually low antibody responses to various antigens.
(19 Jan 1998)
mammary cancer virus of mice Member of the retrovirus subfamily Oncornavirinae, antigenically distinct from the murine leukaemia-sarcoma complex, that is associated with adenocarcinomatous tumours of the mammary gland, commonly latent in wild and laboratory mice and causing cancer only in genetically susceptible strains under certain hormonal influences.
Synonym: Bittner agent, Bittner virus, Bittner's milk factor, mammary cancer virus of mice, milk factor, mouse mammary tumour virus.
(05 Mar 2000)
mammary tumour virus of mice Member of the retrovirus subfamily Oncornavirinae, antigenically distinct from the murine leukaemia-sarcoma complex, that is associated with adenocarcinomatous tumours of the mammary gland, commonly latent in wild and laboratory mice and causing cancer only in genetically susceptible strains under certain hormonal influences.
Synonym: Bittner agent, Bittner virus, Bittner's milk factor, mammary cancer virus of mice, milk factor, mouse mammary tumour virus.
(05 Mar 2000)
mice The common name for the species mus musculus.
(12 Dec 1998)
mice, inbred cftr A strain of mice widely studied as a model for cystic fibrosis. These mice are generated from embryonic stem cells in which the cftr (cystic fibrosis transmembrane conductance regulator) gene is inactivated by gene targeting. As a result, all mice have one copy of this altered gene in all their tissues. Mice homozygous for the disrupted gene exhibit many features common to young cystic fibrosis patients, including failure to thrive, meconium ileus, and alteration of mucous and serous glands.
(12 Dec 1998)
mice, inbred hrs Homozygous, permanently near-hairless mice which lose their hair at about 10 days of age.
(12 Dec 1998)
mice, inbred mdx A strain of mice arising from a spontaneous mutation (mdx) in inbred c57bl mice. This mutation is x chromosome-linked and produces viable homozygous animals that lack the muscle protein dystrophin, have high serum levels of muscle enzymes, and possess histological lesions similar to human muscular dystrophy. The histological features, linkage, and map position of mdx make these mice a worthy animal model of duchenne muscular dystrophy.
(12 Dec 1998)
mice, inbred mrl lpr A mouse substrain that is genetically predisposed to the development of systemic lupus erythematosus-like syndrome, which has been found to be clinically similar to the human disease. It has been determined that this mouse strain carries a mutation in the fas gene. Also, the mrl/lpr is a useful model to study behavioural and cognitive deficits found in autoimmune diseases and the efficacy of immunosuppressive agents.
(12 Dec 1998)
mice, inbred nod A strain of non-obese diabetic mice developed in japan that has been widely studied as a model for T-cell-dependent autoimmune insulin-dependent diabetes mellitus in which insulitis is a major histopathologic feature, and in which genetic susceptibility is strongly MHC-linked.
(12 Dec 1998)
mice, inbred sencar Mice selectively bred for hypersusceptibility to two-stage chemical skin carcinogenesis. They are also hypersusceptible to uv radiation tumourigenesis with single high-dose, but not chronic low-dose, exposures. Sencar (sensitive to carcinogenesis) mice are used in research as an animal model for tumour production.
(12 Dec 1998)
mice, inbred strains Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations, or by parent x offspring matings carried out with certain restrictions. All animals within an inbred strain trace back to a common ancestor in the twentieth generation.
(12 Dec 1998)
mice, jimpy Myelin-deficient mutants which are from the inbred tabby-jimpy strain.
(12 Dec 1998)
mice, knockout Mice whose genome contains a gene whose function has been disrupted, or "knocked-out". A common method of producing disabled genes using recombinant DNA technology is by inserting an antibiotic resistance gene into the normal DNA sequence of a clone of the gene being studied. This disrupts the gene's action, thereby preventing it from making an active protein product. Cells in which this transfer is successful are then injected into mouse embryos, producing chimeric mice. These mice are bred to yield a strain in which all the cells contain the knocked-out gene. Knockout mice are used as animal models for various diseases, such as cystic fibrosis, and are helping to clarify the functions of the genes studied within the fields of immunology, cancer genetics, and developmental biology.
(12 Dec 1998)
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