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rHuEpo recombinant human erythropoietin
EP echo planar; ectopic pregnancy; edible portion; electrophoresis; electrophysiologic; electroprecipit...
EPE erythropoietin-producing enzyme
EPO eosinophil peroxidase; erythropoiesis; erythropoietin; evening primrose-oil; exclusive provider orga...
EPOR erythropoietin receptor
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r-HuEPO Human recombinant erythropoietin
r-HuEPO Recombinant Human Erythropoietin
R-EPO Recombinant erythropoietin
rEpo Recombinant human erythropoietin
hrIL-1 beta Human recombinant interleukin-1 beta
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erythropoietin, recombinant Erythropoietin prepared by recombinant DNA technology.
(12 Dec 1998)
receptors, erythropoietin Cell surface proteins that bind erythropoietin with high affinity and trigger intracellular changes influencing the behaviour of cells.
(12 Dec 1998)
serum erythropoietin <protein> Erythropoietin is a protein hormone which is produced by specialised cells in the kidneys. These cells are sensitive to low arterial oxygen concentration and will release erythropoietin when oxygen is low. Erythropoietin stimulates the bone marrow to produce more red blood cells (to increase the oxygen caring capacity of the blood). The measurement of this hormone in the bloodstream can indicate bone marrow disorders or kidney disease. Normal levels of erythropoietin are 0 to 19 mU/ml (milliunits per millilitre). Elevated levels can be seen in polycythaemia vera. Lower than normal values are seen in chronic renal failure.
(27 Sep 1997)
erythropoietin <growth factor, hormone> Erythropoietin is a Glycoprotein (46 kD) hormone produced by specialised cells in the kidneys that regulates the production of red blood cells in the marrow.
These cells are sensitive to low arterial oxygen concentration and will release erythropoietin when oxygen is low. Erythropoietin stimulates the bone marrow to produce more red blood cells (to increase the oxygen caring capacity of the blood).
The measurement of this hormone in the bloodstream can indicate bone marrow disorders or kidney disease. Normal levels of erythropoietin are 0 to 19 mU/ml (milliunits per millilitre).
Elevated levels can be seen in polycythaemia rubra vera. Lower than normal values are seen in chronic renal failure.Recombinant erythopoeitin is now being used therapeutically in patients.
Acronym: EPO
(27 Sep 1997)
recombinant <molecular biology> A cell or an individual with a new combination of genes not found together in either parent, usually applied to linked genes.
(18 Nov 1997)
recombinant clone <molecular biology> Clones containing recombinant DNA molecules.
See: recombinant DNA technologies.
(14 Oct 1997)
recombinant clones Clones containing recombinant DNA molecules.
(12 Dec 1998)
recombinant DNA <molecular biology> Spliced DNA formed from two or more different sources that have been cleaved by restriction enzymes and joined by ligases.
(18 Nov 1997)
recombinant DNA molecules A combination of DNA molecules of different origin that are joined using recombinant DNA technology.
(12 Dec 1998)
recombinant DNA technologies Procedures used to join together DNA segments in a cell-free system (an environment outside a cell ororganism). Under appropriate conditions, a recombinant DNA molecule canenter a cell and replicate there, either autonomously or after it hasbecome integrated into a cellular chromosome.
(09 Oct 1997)
recombinant DNA technology A series of procedures used to join together (recombine) DNA segments. A recombinant DNA molecule is constructed (recombined) from segments from 2 or more different DNA molecules. Under certain conditions, a recombinant DNA molecule can enter a cell and replicate there, autonomously (on its own) or after it has become integrated into a chromosome.
(12 Dec 1998)
recombinant fusion proteins Proteins that are the result of genetic engineering. A regulatory part or promoter of one or more genes is combined with a structural gene. The fusion protein is formed after transcription and translation of the fused gene. This type of fusion protein is used in the study of gene regulation or structure-activity relationships. They might also be used clinically as targeted toxins (immunotoxins).
(12 Dec 1998)
recombinant proteins Proteins prepared by recombinant DNA technology.
(12 Dec 1998)
recombinant strain <molecular biology> A cell or an individual with a new combination of genes not found together in either parent, usually applied to linked genes.
(18 Nov 1997)
recombinant vector A vector into which a foreign DNA has been inserted.
Synonym: vector.
(05 Mar 2000)
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