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AChRs Acetylcholine Receptors
RA radioactive; ragocyte; ragweed antigen; rapidly adapting [receptors]; reactive arthritis; reciprocal...
CLD chloride diarrhea; chronic liver disease; chronic lung disease; congenital limb deficiency; crystal ...
MLC minimum lethal concentration; mixed leukocyte culture; mixed ligand chelate; mixed lymphocyte concen...
MLCT metal-to-ligand charge transfer
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APO2L AP02 ligand
CD30L CD30 ligand
CD40L CD40 Ligand
CD40L CD40-CD40 ligand
CD95L CD95 ligand
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ambident ligand <chemistry> A ligand that can donate electrons through two or more atoms on their molecule.
(05 Feb 1998)
cyanocobalamin beta-ligand transferase <enzyme> Cytosolic enzyme utilizing fad, NADPH and reduced glutathione; forms glutathionylcobalamin from cyanocobalamin
Registry number: EC 2.5.1.-
Synonym: ccbl transferase
(26 Jun 1999)
ELAM-1 ligand fucosyltransferase <enzyme> Directs the expression of an elam-1 ligand; an alpha(1,3) fucosyltransferase
Registry number: EC 2.4.1.-
Synonym: elft protein, elft gene product
(26 Jun 1999)
ligand <chemistry, immunology> Any molecule that binds to another, in normal usage a soluble molecule such as a hormone or neurotransmitter, that binds to a receptor. The decision as to which is the ligand and which the receptor is often a little arbitrary when the broader sense of receptor is used (where there is no implication of transduction of signal). In these cases it is probably a good rule to consider the ligand to be the smaller of the two thus in a lectin sugar interaction, the sugar would be the ligand (even though it is attached to a much larger molecule, recognition is of the saccharide).
(18 Nov 1997)
ligand binding site The site on a protein's surface that binds a ligand; equivalent to the active site if the ligand is the substrate of an enzyme.
(05 Mar 2000)
ligand-gated channel A class of ion channel's whose ionic permeability is regulated by cell membrane receptors that respond to specific extracellular chemical signals.
(05 Mar 2000)
ligand gated ion channel A transmembrane ion channel whose permeability is increased by the binding of a specific ligand, typically a neurotransmitter at a chemical synapse. The permeability change is often drastic, such channels let through effectively no ions when shut, but allow passage at up to 10exp7 ions sexp 1 when a ligand is bound. Recently, the receptors for both acetylcholine and GABA have been found to share considerable sequence homology, implying that there may be a family of structurally related ligand gated ion channels.
(18 Nov 1997)
ligand induced endocytosis The formation of coated pits and then coated vesicles as a consequence of the interaction of ligand with receptors, which then interact with clathrin and associated proteins (coatomers) on the cytoplasmic face of the plasma membrane and come together to form a pit. Not all coated vesicle uptake of receptors requires receptor occupancy.
(18 Nov 1997)
adrenergic receptors Reactive components of effector tissues, most of which are innervated by adrenergic postganglionic fibres of the sympathetic nervous system. Such receptor's can be activated by norepinephrine and/or epinephrine and by various adrenergic drugs; receptor activation results in a change in effector tissue function, such as contraction of arteriolar muscles or relaxation of bronchial muscles; adrenergic receptor's are divided into alpha-receptor's and beta-receptor's, on the basis of their response to various adrenergic activating and blocking agents.
Synonym: adrenoceptor, adrenoreceptors.
(05 Mar 2000)
alpha-adrenergic receptors Adrenergic receptor's in effector tissues capable of selective activation and blockade by drugs; conceptually derived from the ability of certain agents, such as phenoxybenzamine, to block only some adrenergic receptor's and of other agents, such as methoxamine, to activate only the same adrenergic receptor's. Such receptor's are designated as alpha-receptors. Their activation results in physiological responses such as increased peripheral vascular resistance, mydriasis, and contraction of pilomotor muscles.
(05 Mar 2000)
ANP clearance receptors Cell surface proteins that bind atrial natriuretic peptide and ANP fragments without initiating biological action.
(05 Mar 2000)
ANP receptors Cell surface receptors for atrial natriuretic peptide that have a single transmembrane spanning element; these have integral kinase and guanylate cyclase domains.
(05 Mar 2000)
B-cell antigen receptors In the primary immune response immunoglobulin D and monomeric immunoglobulin M are the B-cell antigen receptors. On memory B-cells, other immunoglobulin molecules can serve as antigen receptors.
(05 Mar 2000)
beta-adrenergic receptors Adrenergic receptor's in effector tissues capable of selective activation and blockade by drugs; conceptually derived from the ability of certain agents, such as propranolol, to block only some adrenergic receptor's and of other agents, such as isoproterenol, to activate only the same adrenergic receptor's. Such receptor's are designated as beta-receptors. Their activation results in physiological responses such as increases in cardiac rate and force of contraction (b1), and relaxation of bronchial and vascular smooth muscle (b2).
(05 Mar 2000)
mannose-6-phosphate receptors Receptors in Golgi apparatus to which newly synthesised proteins that are destined to enter lysosomes bind.
(05 Mar 2000)
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  • Receptors, TNF-Related Apoptosis-Inducing Ligand - »õâ Tumor necrosis factor receptor family members that are widely expressed and play a role in regulation of peripheral immune responses and APOPTOSIS. The receptors are specific for TNF-RELATED APOPTOSIS-INDUCING LIGAND and signal via conserved death domains that associate with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.
    Synonyms : APO2 Receptor, DCR2 Receptor, DR4 Receptor, DR5 Receptor, Death Receptor-4, Death Receptor-5, Receptor, TRAIL-1, Receptor, TRAIL-2, Receptor, TRAIL-4, Receptors, Tumor Necrosis Factor, Member 10a, Receptors, Tumor Necrosis Factor, Member 10d, TRAIL Receptor 1
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